Search Results - "Scherbak, Nikolai"

The insecticide permethrin induces transgenerational behavioral changes linked to transcriptomic and epigenetic alterations in zebrafish (Danio rerio) by Blanc, Mélanie, Antczak, Philipp, Cousin, Xavier, Grunau, Christoph, Scherbak, Nikolai, Rüegg, Joëlle, Keiter, Steffen H.

“…The pyrethroid insecticide permethrin is widely used for agricultural and domestic purposes. Previous data indicated that it acts as a developmental…”
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Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes Metab J 2023;47:668-81) by Scherbak, Nikolai N, Kruse, Robert, Nyström, Thomas, Jendle, Johan

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Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models by Alijagic, Andi, Sinisalu, Lisanna, Duberg, Daniel, Kotlyar, Oleksandr, Scherbak, Nikolai, Engwall, Magnus, Orešič, Matej, Hyötyläinen, Tuulia

“…[Display omitted] •PFAS causes dose-dependent, non-monotonic responses on multiple metabolites.•PFAS exposure is linked with changes in bile acid and glucose…”
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Immunotoxic, genotoxic, and endocrine disrupting impacts of polyamide microplastic particles and chemicals by Alijagic, Andi, Kotlyar, Oleksandr, Larsson, Maria, Salihovic, Samira, Hedbrant, Alexander, Eriksson, Ulrika, Karlsson, Patrik, Persson, Alexander, Scherbak, Nikolai, Färnlund, Kim, Engwall, Magnus, Särndahl, Eva

“…[Display omitted] •Identified polyamide chemicals included starting material and several plastics additives.•Prolonged polyamide particle exposure led to the…”
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Effect of perfluorooctanesulfonic acid (PFOS) on the liver lipid metabolism of the developing chicken embryo by Geng, Dawei, Musse, Ayan Au, Wigh, Viktoria, Carlsson, Cecilia, Engwall, Magnus, Orešič, Matej, Scherbak, Nikolai, Hyötyläinen, Tuulia

“…Perfluorooctanesulfonate (PFOS) is a well-known contaminant in the environment and it has shown to disrupt multiple biological pathways, particularly those…”
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Stable expression of HIV-1 MPER extended epitope on the surface of the recombinant probiotic bacteria Escherichia Coli Nissle 1917 using CRISPR/Cas9 by Ninyio, Nathaniel, Schmitt, Katherina, Sergon, Gladys, Nilsson, Charlotta, Andersson, Sören, Scherbak, Nikolai

“…Mucosal vaccines have the potential to induce protective immune responses at the sites of infection. Applying CRISPR/Cas9 editing, we aimed to develop a…”
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Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial by Scherbak, Nikolai N, Kruse, Robert, Nyström, Thomas, Jendle, Johan

“…Diabetes is a chronic disease with several long-term complications. Several glucose-lowering drugs are used to treat type 2 diabetes mellitus (T2DM), e.g.,…”
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Correction: Stable expression of HIV-1 MPER extended epitope on the surface of the recombinant probiotic bacteria Escherichia Coli Nissle 1917 using CRISPR/Cas9 by Ninyio, Nathaniel, Schmitt, Katharina, Sergon, Gladys, Nilsson, Charlotta, Andersson, Sören, Scherbak, Nikolai

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Zebrafish Androgen Receptor: Isolation, Molecular, and Biochemical Characterization by Hossain, Mohammad Sorowar, Larsson, Anders, Scherbak, Nikolai, Olsson, Per-Erik, Orban, Laszlo

“…Androgens play an important role in male sexual differentiation and development. They exert their function by binding to and activating the androgen receptor…”
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Lactobacillus rhamnosus GR-1 enhances NF-kappaB activation in Escherichia coli-stimulated urinary bladder cells through TLR4 by Karlsson, Mattias, Scherbak, Nikolai, Reid, Gregor, Jass, Jana

“…Epithelial cells of the urinary tract recognize pathogenic bacteria through pattern recognition receptors on their surface, such as toll-like receptors (TLRs),…”
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Reference gene selection for qPCR is dependent on cell type rather than treatment in colonic and vaginal human epithelial cell lines by Jacobsen, Annette V, Yemaneab, Bisrat T, Jass, Jana, Scherbak, Nikolai

“…The ability of commensal bacteria to influence gene expression in host cells under the influence of pathogenic bacteria has previously been demonstrated,…”
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Particle Safety Assessment in Additive Manufacturing: From Exposure Risks to Advanced Toxicology Testing by Alijagic, Andi, Engwall, Magnus, Särndahl, Eva, Karlsson, Helen, Hedbrant, Alexander, Andersson, Lena, Karlsson, Patrik, Dalemo, Magnus, Scherbak, Nikolai, Färnlund, Kim, Larsson, Maria, Persson, Alexander

“…Additive manufacturing (AM) or industrial three-dimensional (3D) printing drives a new spectrum of design and production possibilities; pushing the boundaries…”
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A Novel Nanosafety Approach Using Cell Painting, Metabolomics, and Lipidomics Captures the Cellular and Molecular Phenotypes Induced by the Unintentionally Formed Metal-Based (Nano)Particles by Alijagic, Andi, Scherbak, Nikolai, Kotlyar, Oleksandr, Karlsson, Patrik, Wang, Xuying, Odnevall, Inger, Benada, Oldřich, Amiryousefi, Ali, Andersson, Lena, Persson, Alexander, Felth, Jenny, Andersson, Henrik, Larsson, Maria, Hedbrant, Alexander, Salihovic, Samira, Hyötyläinen, Tuulia, Repsilber, Dirk, Särndahl, Eva, Engwall, Magnus

“…Additive manufacturing (AM) or industrial 3D printing uses cutting-edge technologies and materials to produce a variety of complex products. However, the…”
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A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis by Krivospitskaya, Olesya, Elmabsout, Ali Ateia, Sundman, Eva, Söderström, Leif A, Ovchinnikova, Olga, Gidlöf, Andreas C, Scherbak, Nikolai, Norata, Giuseppe Danilo, Samnegård, Ann, Törmä, Hans, Abdel-Halim, Samy M, Jansson, Jan-Håkan, Eriksson, Per, Sirsjö, Allan, Olofsson, Peder S

“…All-trans retinoic acid, controlled by cytochrome P450, family 26 (CYP26) enzymes, potentially has beneficial effects in atherosclerosis treatment. This study…”
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Characterization of antibodies for quantitative determination of spiggin protein levels in male and female three-spined stickleback (Gasterosteus aculeatus) by Berg, Håkan, Scherbak, Nikolai, Liimatta, Harri, Hoffmann, Erik, Karlsson, Johnny, Olsson, Per-Erik

“…Spiggin is an adhesive glycoprotein produced in the kidney of sticklebacks during the breeding season and is subsequently secreted into the urinary bladder…”
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Predicting Chemical-Induced Liver Toxicity Using High-Content Imaging Phenotypes and Chemical Descriptors: A Random Forest Approach by Chavan, Swapnil, Scherbak, Nikolai, Engwall, Magnus, Repsilber, Dirk

“…Hepatotoxicity is a major reason for the withdrawal or discontinuation of drugs from clinical trials. Thus, better tools are needed to filter potential…”
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Effects of perfluorooctane sulfonate on genes controlling hepatic fatty acid metabolism in livers of chicken embryos by Jacobsen, Annette V., Nordén, Marcus, Engwall, Magnus, Scherbak, Nikolai

“…Per- and polyfluoroalkyl substances (PFAS) are synthetic surfactants with a wide variety of applications; however, due to their stability, they are…”
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Mixture-specific gene expression in zebrafish (Danio rerio) embryos exposed to perfluorooctane sulfonic acid (PFOS), perfluorohexanoic acid (PFHxA) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) by Blanc, Mélanie, Kärrman, Anna, Kukucka, Petr, Scherbak, Nikolai, Keiter, Steffen

“…Perfluorooctane sulfonic acid (PFOS) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) are persistent organic pollutants of high concern because of their…”
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Multi- and transgenerational effects following early-life exposure of zebrafish to permethrin and coumarin 47: Impact on growth, fertility, behavior and lipid metabolism by Blanc, Mélanie, Cormier, Bettie, Hyötyläinen, Tuulia, Krauss, Martin, Scherbak, Nikolai, Cousin, Xavier, Keiter, Steffen H.

“…Transgenerational effects induced by environmental stressors are a threat to ecosystems and human health. However, there is still limited observation and…”
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Antibacterial effects of Lactobacillus and bacteriocin PLNC8 alpha beta on the periodontal pathogen Porphyromonas gingivalis by Khalaf, Hazem, Sowdamini Nakka, Sravya, Sandén, Camilla, Svärd, Anna, Hultenby, Kjell, Scherbak, Nikolai, Aili, Daniel, Bengtsson, Torbjorn

“…Background: The complications in healthcare systems associated with antibiotic-resistant microorganisms have resulted in an intense search for new effective…”
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