Search Results - "Schepisi, Chiara"
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Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion
Published in Scientific reports (20-07-2015)“…Mechanisms of gender-specific synaptic plasticity in the striatum, a brain region that controls motor, cognitive and psychiatric functions, remain unclear…”
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Effects of the 5HT2C antagonist SB242084 on the pramipexole-induced potentiation of water contrafreeloading, a putative animal model of compulsive behavior
Published in Psychopharmacology (01-05-2013)“…Rationale In rats, quinpirole, a dopaminergic D2/D3 receptor agonist, elicits both hyperdipsia and water “contrafreeloading” (CFL), a putative model of…”
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Functional alterations of the dopaminergic and glutamatergic systems in spontaneous α-synuclein overexpressing rats
Published in Experimental neurology (01-01-2017)“…The presence of α-synuclein (α-syn) in Lewy bodies and Lewy neurites is an important characteristic of the neurodegenerative processes of substantia nigra pars…”
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Differences in the structure of drinking, cart expression and dopamine turnover between polydipsic and non polydipsic rats in the quinpirole model of psychotic polydipsia
Published in Psychopharmacology (01-10-2014)“…Rationale Dopaminergic D2/D3 agonist quinpirole (QNP) elicits nonregulatory drinking in rats, a model of psychotic polydipsia. Why only a fraction of…”
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Clomipramine, but not haloperidol or aripiprazole, inhibits quinpirole-induced water contrafreeloading, a putative animal model of compulsive behavior
Published in Psychopharmacologia (01-12-2011)“…Rationale Repeated administrations of the D2/D3 agonist quinpirole (QNP) to rats elicit an antieconomical pattern of drinking called “contrafreeloading” (CFL),…”
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Inhibition of hippocampal plasticity in rats performing contrafreeloading for water under repeated administrations of pramipexole
Published in Psychopharmacology (01-02-2016)“…Rationale Compulsive symptoms develop in patients exposed to pramipexole (PPX), a dopaminergic agonist with high selectivity for the D3 receptor. Consistently,…”
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Profile of gantenerumab and its potential in the treatment of Alzheimer's disease
Published in Drug design, development and therapy (01-01-2013)“…Alzheimer's disease, which is characterized by gradual cognitive decline associated with deterioration of daily living activities and behavioral disturbances…”
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Opposite roles of dopamine and orexin in quinpirole-induced excessive drinking: a rat model of psychotic polydipsia
Published in Psychopharmacologia (01-08-2010)“…Rationale Repeated administration of the dopamine D2/D3 agonist quinpirole (QNP) progressively increases non-regulatory water intake. This effect may model…”
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Profile of gantenerumab and its potential in the treatment of Alzheimer's disease [Corrigendum]
Published in Drug design, development and therapy (01-01-2014)“…1359-1364.On page 1362, left hand column, last sentence under Functional studies:The effects of gantenerumab on cognitive assessment in the Morris water maze…”
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