Search Results - "Schemper, M."
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Statistical controversies in clinical research: the importance of importance
Published in Annals of oncology (01-07-2016)“…We define the notion of ‘importance’ of prognostic factors in studies of survival and suggest quantifying it by the Schemper–Henderson measure of explained…”
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2
Parameters influencing FVIII pharmacokinetics in patients with severe and moderate haemophilia A
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2015)“…Summary In haemophilia A patients factor VIII (FVIII) recovery and half‐life can vary substantially. There are parameters known to modulate FVIII…”
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The relative importance of prognostic factors in studies of survival
Published in Statistics in medicine (30-12-1993)“…The relative importance of prognostic factors in regression can be measured either by standardized regression coefficients or by percentages of explained…”
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The explained variation in proportional hazards regression
Published in Biometrika (01-03-1990)“…Two new measures of the proportion of the variation of possibly censored survival times explained by a given proportional hazards model are presented. It is…”
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Lack of impact of platinum dose intensity on the outcome of ovarian cancer patients: 10-year results of a prospective randomised phase III study comparing carboplatin–cisplatin with cyclophosphamide–cisplatin
Published in European journal of cancer (1990) (01-05-2003)“…This prospective multicentre phase III trial was conducted to assess whether increased platinum dose intensity (DI) by combining carboplatin with cisplatin has…”
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A meta‐analysis of low dose aspirin for the prevention of intrauterine growth retardation
Published in BJOG : an international journal of obstetrics and gynaecology (01-04-1997)“…Objective To determine more precisely the effect of prophylactic low dose aspirin on intrauterine growth retardation and perinatal mortality. Design…”
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Alterations in nocturnal serum melatonin levels in humans with growth and aging
Published in The journal of clinical endocrinology and metabolism (01-03-1988)“…The available data on potential alterations in serum melatonin (MLT) levels during a human lifetime are fragmentary and inconsistent. We, therefore, measured…”
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A note on quantifying follow-up in studies of failure time
Published in Controlled clinical trials (01-08-1996)Get full text
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Antibiotic treatment in preterm premature rupture of membranes and neonatal morbidity: A metaanalysis
Published in American journal of obstetrics and gynecology (01-02-1996)“…OBJECTIVE: We performed a metaanalysis of seven published randomized clinical trials to estimate more precisely the effect of prophylactic antibiotics on…”
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Topical versus peribulbar anesthesia in clear corneal cataract surgery
Published in Journal of cataract and refractive surgery (01-05-1996)“…To evaluate the efficacy of topical anesthesia as an alternative to peribulbar anesthesia in clear corneal cataract surgery. Department of Ophthalmology,…”
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Further results on the explained variation in proportional hazards regression
Published in Biometrika (01-03-1992)“…Summary Two competing measures of the proportion of variation of possibly censored survival times explained by a given proportional hazards model are compared…”
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A solution to the problem of separation in logistic regression
Published in Statistics in medicine (30-08-2002)“…The phenomenon of separation or monotone likelihood is observed in the fitting process of a logistic model if the likelihood converges while at least one…”
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Skin tumors in photochemotherapy for psoriasis: a single-center follow-up of 496 patients
Published in Dermatology (Basel) (01-01-1996)“…The significance of oral psoralen photochemotherapy (PUVA) for the development of nonmelanoma skin cancers (NMSC) is still controversial. We evaluated 496…”
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Non-parametric analysis of treatment-covariate interaction in the presence of censoring
Published in Statistics in medicine (01-12-1988)“…The demonstration of varying treatment efficacy among different subsets of patients is an important part of the analysis of clinical trials. The paper…”
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15
Serum melatonin in central precocious puberty is lower than in age-matched prepubertal children
Published in The journal of clinical endocrinology and metabolism (01-10-1991)“…In children a progressive decrease in nocturnal serum melatonin (MT) has been shown with advancing age, suggesting a reduction in the amplitude of the…”
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Predictive accuracy and explained variation
Published in Statistics in medicine (30-07-2003)“…Measures of the predictive accuracy of regression models quantify the extent to which covariates determine an individual outcome. Explained variation measures…”
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Outcome of watchful waiting in asymptomatic severe mitral regurgitation
Published in Circulation (New York, N.Y.) (09-05-2006)“…The management of asymptomatic severe mitral regurgitation remains controversial. The aim of this study was to evaluate the outcome of a watchful waiting…”
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Statins but not angiotensin-converting enzyme inhibitors delay progression of aortic stenosis
Published in Circulation (New York, N.Y.) (07-09-2004)“…Recently, statins and angiotensin-converting enzyme inhibitors (ACEIs) have been shown to slow aortic valve calcium accumulation. Although several studies also…”
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Mild and moderate aortic stenosis: Natural history and risk stratification by echocardiography
Published in European heart journal (01-02-2004)“…To define the natural history and predictors of outcome in mild and moderate aortic stenosis (AS). One hundred and seventy-six consecutive asymptomatic…”
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Role of a heart valve clinic programme in the management of patients with aortic stenosis
Published in European heart journal cardiovascular imaging (01-02-2017)“…Aims We sought to assess the efficacy of a heart valve clinic (HVC) follow-up programme for patients with severe aortic stenosis (AS). Methods and results…”
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