Search Results - "Schembri, Stuart"

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease by Dicker, Alison J., PhD, Crichton, Megan L., MFM, Pumphrey, Eleanor G, Cassidy, Andrew J., PhD, Suarez-Cuartin, Guillermo, MD, Sibila, Oriol, MD, Furrie, Elizabeth, PhD, Fong, Christopher J, Ibrahim, Wasyla, Brady, Gill, BSc, Einarsson, Gisli G., PhD, Elborn, J. Stuart, MD, Schembri, Stuart, MD, Marshall, Sara E., PhD, Palmer, Colin N.A., PhD, Chalmers, James D., PhD

“…Background Neutrophil extracellular traps (NETs) have been observed in the airway in patients with chronic obstructive pulmonary disease (COPD), but their…”
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The effect of changes to GOLD severity stage on long term morbidity and mortality in COPD by Flynn, Robert W V, MacDonald, Thomas M, Chalmers, James D, Schembri, Stuart

“…The Global Initiative for Chronic Obstructive Lung Disease (GOLD) severity stage classifies Chronic Obstructive Pulmonary Disease (COPD) into groups based on…”
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The Impact of Tiotropium on Mortality and Exacerbations When Added to Inhaled Corticosteroids and Long-Acting β-Agonist Therapy in COPD by Short, Philip M., MBChB, Williamson, Peter A., MBChB, Elder, Douglas H.J., MBChB, Lipworth, Samuel I.W., BSc, Schembri, Stuart, MD, Lipworth, Brian J., MD

“…Background Tiotropium has been shown to improve lung function, quality of life, and exacerbations and reduce mortality when compared with placebo in COPD. It…”
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Respiratory Symptoms, Pulmonary Function, and Markers of Inflammation Among Bar Workers Before and After a Legislative Ban on Smoking in Public Places by Menzies, Daniel, Nair, Arun, Williamson, Peter A, Schembri, Stuart, Al-Khairalla, Mudher Z. H, Barnes, Martyn, Fardon, Tom C, McFarlane, Lesley, Magee, Gareth J, Lipworth, Brian J

“…CONTEXT Scotland prohibited smoking in confined public places on March 26, 2006. OBJECTIVE To investigate the association of smoke-free legislation with…”
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Determinants of motivation to quit in smokers screened for the early detection of lung cancer: a qualitative study by Young, Ben, Vedhara, Kavita, Kendrick, Denise, Littleford, Roberta, Robertson, John F R, Sullivan, Frank M, Schembri, Stuart, das Nair, Roshan

“…The promotion of smoking cessation within lung cancer screening could lead to benefits for smoking-related disease and improve cost-effectiveness of screening…”
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The effect of optimised patient information materials on recruitment in a lung cancer screening trial: an embedded randomised recruitment trial by Parker, Adwoa, Knapp, Peter, Treweek, Shaun, Madhurasinghe, Vichithranie, Littleford, Roberta, Gallant, Stephanie, Sullivan, Frank, Schembri, Stuart, Rick, Jo, Graffy, Jonathan, Collier, David J, Eldridge, Sandra, Kennedy, Anne, Bower, Peter

“…Written participant information materials are important for ensuring that potential trial participants receive necessary information so that they can provide…”
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Effect of Statins on Total Cholesterol Concentrations, Cardiovascular Morbidity, and All-Cause Mortality in Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study by Sheng, Xia, MPH, Murphy, Michael J., FRCP, MacDonald, Thomas M., FRCP, Schembri, Stuart, MD, FRCP, Simpson, William, FRCPath, Winter, Janet, RCN, FRCP, Winter, John H., FRCP, Wei, Li, PhD

“…Abstract Background The benefit of statin use on total cholesterol (TC) concentration has not been studied previously in patients with chronic obstructive…”
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CONSERVATIVE MANAGEMENT OF SECONDARY PNEUMOTHORAX COMPLICATED BY COMORBID DEMENTIA: A CASE STUDY by GLOECKL, SARINA, TURNER, MARIANNE T, SCHEMBRI, STUART

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Predictors of Mortality in Hospitalized Adults with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. A Systematic Review and Meta-analysis by Singanayagam, Aran, Schembri, Stuart, Chalmers, James D.

“…This paper aims to systematically review the literature to identify clinically important factors that predict mortality after hospitalization for acute…”
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Tiotropium versus salmeterol in COPD by Schembri, Stuart

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Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging by Sullivan, Frank M, Mair, Frances S, Anderson, William, Armory, Pauline, Briggs, Andrew, Chew, Cindy, Dorward, Alistair, Haughney, John, Hogarth, Fiona, Kendrick, Denise, Littleford, Roberta, McConnachie, Alex, McCowan, Colin, McMeekin, Nicola, Patel, Manish, Rauchhaus, Petra, Ritchie, Lewis, Robertson, Chris, Robertson, John, Robles-Zurita, Jose, Sarvesvaran, Joseph, Sewell, Herbert, Sproule, Michael, Taylor, Thomas, Tello, Agnes, Treweek, Shaun, Vedhara, Kavita, Schembri, Stuart

“…The EarlyCDT-Lung test is a high-specificity blood-based autoantibody biomarker that could contribute to predicting lung cancer risk. We report on the results…”
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Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy? by Harrison, Michelle T, Short, Philip, Williamson, Peter A, Singanayagam, Aran, Chalmers, James D, Schembri, Stuart

“…Evidence suggests that platelets play a significant role in inflammation in addition to their role in thrombosis. Systemic inflammation is linked to poor short…”
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Inhaled Corticosteroids for Chronic Obstructive Pulmonary Disease--The Shifting Treatment Paradigm by Wilkie, Morven, Finch, Simon, Schembri, Stuart

“…Chronic obstructive pulmonary disease (COPD) guidelines suggest using inhaled corticosteroids (ICS) in patients with severe airflow limitation or those at high…”
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Simplification of the IDSA/ATS criteria for severe CAP using meta-analysis and observational data by SALIH, Waleed, SCHEMBRI, Stuart, CHALMERS, James D

“…The 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) guidelines proposed "minor" criteria to predict intensive care unit…”
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Non-typeable Haemophilus influenzae protein vaccine in adults with COPD: A phase 2 clinical trial by Wilkinson, Tom M.A, Schembri, Stuart, Brightling, Christopher, Bakerly, Nawar D, Lewis, Keir, MacNee, William, Rombo, Lars, Hedner, Jan, Allen, Martin, Walker, Paul P, De Ryck, Iris, Tasciotti, Annaelisa, Casula, Daniela, Moris, Philippe, Testa, Marco, Arora, Ashwani K

“…Highlights•An investigational NTHi vaccine was tested for the first time in adults with COPD. •The vaccine had acceptable safety and reactogenicity…”
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Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD by Dicker, Alison J, Crichton, Megan L, Cassidy, Andrew J, Brady, Gill, Hapca, Adrian, Tavendale, Roger, Einarsson, Gisli G, Furrie, Elizabeth, Elborn, J Stuart, Schembri, Stuart, Marshall, Sara E, Palmer, Colin N A, Chalmers, James D

“…In cystic fibrosis and bronchiectasis, genetic mannose binding lectin (MBL) deficiency is associated with increased exacerbations and earlier mortality;…”
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Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial by Sullivan, F M, Farmer, Eoghan, Mair, Frances S, Treweek, Shaun, Kendrick, Denise, Jackson, Cathy, Robertson, Chris, Briggs, Andrew, McCowan, Colin, Bedford, Laura, Young, Ben, Vedhara, Kavita, Gallant, Stephanie, Littleford, Roberta, Robertson, John, Sewell, Herb, Dorward, Alistair, Sarvesvaran, Joseph, Schembri, Stuart

“…Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The…”
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Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT) by Young, Ben, Bedford, Laura, das Nair, Roshan, Gallant, Stephanie, Littleford, Roberta, Robertson, John F.R., Schembri, Stuart, Sullivan, Frank M., Vedhara, Kavita, Kendrick, Denise

“…Rationale, aims, and objectives High response rates to research questionnaires can help to ensure results are more representative of the population studied and…”
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Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study by Short, Philip M, Lipworth, Samuel I W, Elder, Douglas H J, Schembri, Stuart, Lipworth, Brian J

“…Objective To examine the effect of β blockers in the management of chronic obstructive pulmonary disease (COPD), assessing their effect on mortality, hospital…”
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Quantifying the real life risk profile of inhaled corticosteroids in COPD by record linkage analysis by Flynn, Rob W, MacDonald, Thomas M, Hapca, Adrian, MacKenzie, Isla S, Schembri, Stuart

“…Inhaled corticosteroids (ICS), especially when prescribed in combination with long-acting β2 agonists have been shown to improve COPD outcomes. Although there…”
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