Search Results - "Schelm, J A"

Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase by Vlahos, CJ, Matter, WF, Brown, RF, Traynor-Kaplan, AE, Heyworth, PG, Prossnitz, ER, Ye, RD, Marder, P, Schelm, JA, Rothfuss, KJ

“…Neutrophils contain a multicomponent NADPH oxidase system that is involved in the production of microbicidal oxidants. Stimulation of human neutrophils with…”
Get full text

Activated recombinant human protein C does not attenuate recruitment of neutrophils in rat models of acute inflammation by O'Leary, E C, Schelm, J A, Simpson, P J

“…It has been proposed that the reduction in mortality in animal models of sepsis by activated protein C (APC) is mediated by an antiinflammatory property rather…”
Get more information

The role of serotonin (5HT2) receptor blockade in myocardial reperfusion injury: effects of LY53857 in a canine model of myocardial infarction by Simpson, P J, Schelm, J A, Jakubowski, J A, Smallwood, J K

“…The potential protective effects of serotonin receptor antagonism during the process of acute myocardial infarction were studied in anesthetized male dogs,…”
Get more information

Therapeutic defibrination with ancrod does not protect canine myocardium from reperfusion injury by Simpson, P J, Schelm, J A, Smith, G F

“…The purpose of this study was to determine whether normal fibrinogen contributes to the development of myocardial reperfusion injury by acting as a substrate…”
Get more information

Effect of activation of ATP-dependent potassium channels with (-)-pinacidil and (-)-3-pyridyl pinacidil on infarct size in a canine model of ischemia-reperfusion injury by Smallwood, J K, Schelm, J A, Bemis, K G, Simpson, P J

“…We tested the hypothesis that opening myocardial ATP-dependent K+ (ATP-K) channels by administration of (-)-pinacidil or (-)-3-pyridyl pinacidil…”
Get more information

Inhibition of neutrophil oxidative burst and granule secretion by Wortmannin: Potential role of MAP kinase and renaturable kinases by Sue-A-Quan, Andrea K., Fialkow, Lea, Vlahos, Chris J., Schelm, Judi A., Grinstein, Sergio, Butler, Jeff, Downey, Gregory P.

“…Exposure of neutrophils to a variety of agonists including soluble chemoattractant peptides and cytokines results in degranulation and activation of the…”
Get full text

Estrogen-Mediated Increases in LDL Cholesterol and Foam Cell-Containing Lesions in Human ApoB100xCETP Transgenic Mice by Zuckerman, Steven H, Evans, Glenn F, Schelm, Judi A, Eacho, Patrick I, Sandusky, George

“…The murine double transgenic mouse expressing both human apoB100 and cholesteryl ester transfer protein (CETP), has been used as a model to understand the…”
Get full text

Estrogen-mediated increases in LDL cholesterol and foam cell-containing lesions in human ApoB100×CETP transgenic mice by ZUCKERMAN, S. H, EVANS, G. F, SCHELM, J. A, EACHO, P. I, SANDUSKY, G

“…Abstract —The murine double transgenic mouse expressing both human apoB100 and cholesteryl ester transfer protein (CETP), has been used as a model to…”
Get full text

Inhibition of granulocyte cAMP-phosphodiesterase by rolipram in vivo is not sufficient to protect the canine myocardium from reperfusion injury by Simpson, P J, Schelm, J A, Smallwood, J K, Clay, M P, Lindstrom, T D

“…The purpose of this study was to determine whether the selective type IV cAMP-phosphodiesterase inhibitor rolipram could reduce the reperfusion injury that…”
Get more information