Search Results - "Schellenberger, V."

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  1. 1

    Construction of stabilized proteins by combinatorial consensus mutagenesis by Amin, N., Liu, A.D., Ramer, S., Aehle, W., Meijer, D., Metin, M., Wong, S., Gualfetti, P., Schellenberger, V.

    Published in Protein engineering, design and selection (01-11-2004)
    “…We constructed stabilized variants of β-lactamase (BLA) from Enterobacter cloacae by combinatorial recruitment of consensus mutations. By aligning the…”
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    Selection of a subtilisin-hyperproducing Bacillus in a highly structured environment by NAKI, D, PAECH, C, GANSHAW, G, SCHELLENBERGER, V

    Published in Applied microbiology and biotechnology (01-03-1998)
    “…Mutants that secrete increased amounts of enzyme into a selection medium can be efficiently enriched from large populations of mutagenized microorganisms…”
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    The substrate specificity of Uca pugilator collagenolytic serine protease 1 correlates with the bovine type I collagen cleavage sites by TSU, C. A, PERONA, J. J, SCHELLENBERGER, V, TURCK, C. W, CRAIK, C. S

    Published in The Journal of biological chemistry (29-07-1994)
    “…Affinity-based purification and characterization of the collagenolytic serine protease 1 from Uca pugilator (fiddler crab) hepatopancreas shows that the enzyme…”
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    Extension of in vivo half-life of biologically active peptides via chemical conjugation to XTEN protein polymer by Podust, Vladimir N., Sim, Bee-Cheng, Kothari, Dharti, Henthorn, Lana, Gu, Chen, Wang, Chia-wei, McLaughlin, Bryant, Schellenberger, Volker

    Published in Protein engineering, design and selection (01-11-2013)
    “…XTEN, unstructured biodegradable proteins, have been used to extend the in vivo half-life of genetically fused therapeutic proteins and peptides. To expand the…”
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  8. 8

    Rapid Evolution of Novel Traits in Microorganisms by SELIFONOVA, Olga, VALLE, Fernando, SCHELLENBERGER, Volker

    Published in Applied and Environmental Microbiology (01-08-2001)
    “…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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  9. 9

    Generation of large libraries of random mutants in Bacillus subtilis by PCR-based plasmid multimerization by Shafikhani, S, Siegel, R A, Ferrari, E, Schellenberger, V

    Published in BioTechniques (01-08-1997)
    “…We describe a PCR-based method for the generation of plasmid multimers that can be directly transformed into Bacillus subtilis with very high efficiency. This…”
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  10. 10

    Screening of synthetic peptide libraries with radiolabeled acceptor molecules by Kassarjian, A, Schellenberger, V, Turck, C W

    Published in Peptide research (01-05-1993)
    “…A method has been developed for the identification of specific acceptor molecule-binding sequences from a chemically synthesized peptide library. The peptide…”
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    Protease-catalyzed peptide synthesis: prevention of side reactions in kinetically controlled reactions by Schellenberger, V, Görner, A, Könnecke, A, Jakubke, H D

    Published in Peptide research (01-09-1991)
    “…One major problem in protease-catalyzed peptide synthesis is the occurrence of unwanted proteolytic side reactions. The objective of this study was to…”
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  12. 12

    Role of the S' Subsites in Serine Protease Catalysis. Active-Site Mapping of Rat Chymotrypsin, Rat Trypsin, .alpha.-Lytic Protease, and Cercarial Protease from Schistosoma mansoni by Schellenberger, Volker, Turck, Christoph W, Rutter, William J

    Published in Biochemistry (Easton) (12-04-1994)
    “…The S' subsite specificity of four homologous serine proteases, rat chymotrypsin, rat trypsin, alpha-lytic protease, and cercarial protease from Schistosoma…”
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  13. 13

    Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles by Schellenberger, Volker, Turck, Christoph W, Hedstrom, Lizbeth, Rutter, William J

    Published in Biochemistry (Easton) (27-04-1993)
    “…We have developed a rapid and convenient procedure for the characterization of the S' subsite specificity of serine proteases. A mixture of peptide…”
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  14. 14

    Rapid in vivo evolution of a β-lactamase using phagemids by Long-McGie, Jeffrey, Liu, Amy D., Schellenberger, Volker

    Published in Biotechnology and bioengineering (05-04-2000)
    “…RNA viruses are capable of undergoing extremely rapid evolution due to their high rates of reproduction, small genome size, and a high frequency of spontaneous…”
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  15. 15

    Synthesis and kinetic characterisation of omega-guanidinocarbonic acid ethyl esters as trypsin substrates by Schuster, M, Medvedkin, V N, Schellenberger, V, Mitin YuV, Jakubke, H D

    Published in Biomedica biochimica acta (1990)
    “…Aliphatic omega-guanidinocarbonic acid ethyl esters of different chain length (C3-C6) were synthesized and characterized as 4-toluenesulfonates. The kinetic…”
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  16. 16

    Chymotrypsin-catalyzed fragment coupling synthesis of GnRH-analogs by Hänsicke, A, Krause, E, Bienert, M, Schmidt, M, Kobert, S, Schellenberger, V, Jakubke, H D, Kaufmann, K D

    Published in Biomedica biochimica acta (1991)
    “…D-Xaa6-GnRH analogs (Xaa: Ala, Nal1), Phe, Ser(tBu), Trp) were prepared by chymotrypsin catalyzed 3 + 7 fragment coupling synthesis with conversion rates of…”
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    Substrate preferences of Vsr DNA mismatch endonuclease and their consequences for the evolution of the Escherichia coli K-12 genome by Gläsner, Wolfgang, Merkl, Rainer, Schellenberger, Volker, Fritz, Hans-Joachim

    Published in Journal of molecular biology (1995)
    “…The substrate spectrum of Vsr DNA mismatch endonuclease of Escherichia coli K-12 was investigated using fluorescence-labelled oligonucleotide Substrates and a…”
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  18. 18

    Analysis of enzyme specificity by multiple substrate kinetics by Schellenberger, Volker, Siegel, Ronald A, Rutter, William J

    Published in Biochemistry (Easton) (27-04-1993)
    “…Multiple approaches for screening large sets of compounds for a specific function are of growing interest. The use of substrate mixtures to characterize the…”
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  19. 19

    Penicillin acylase-catalyzed protection and deprotection of amino groups as a promising approach in enzymatic peptide synthesis by Didžiapetris, Remigijus, Drabnig, Barbara, Schellenberger, Volker, Jakubke, Hans-Dieter, S̆vedas, Vytas

    Published in FEBS letters (05-08-1991)
    “…Penicillin acylase from E. coli is able to catalyze both the introduction and the removal of the phenylacetyl group. We have established that phenylacetyl…”
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  20. 20

    Electrostatic effects in the alpha-chymotrypsin-catalyzed acyl transfer. II. Efficiency of nucleophiles bearing charged groups in various locations by Schellenberger, V, Jakubke, H D, Kasche, V

    Published in Biochimica et biophysica acta (30-05-1991)
    “…We investigated the alpha-chymotrypsin-catalyzed acyl transfer to a series of glycine oligomers. It could be established that the electrostatic interactions…”
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