Search Results - "Schellekens, K H"

Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties by Janssen, P A, Niemegeers, C J, Awouters, F, Schellekens, K H, Megens, A A, Meert, T F

“…Comparative studies of the benzisoxazole derivative risperidone (R 64 766) were made with ritanserin, a selective centrally acting serotonin-S2 antagonist and…”
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Tetramisole ( R 8299), A New, Potent Broad Spectrum Anthelmintic by THIENPONT, D, VANPARIJS, O. F. J, RAEYMAEKERS, A. H. M, VANDENBERK, J, DEMOEN, P. J. A, ALLEWIJN, F. T. N, MARSBOOM, R. P. H, NIEMEGEERS, C. J. E, SCHELLEKENS, K. H. L, JANSSEN, PAUL A. J

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Ritanserin reduces abuse of alcohol, cocaine, and fentanyl in rats by Meert, T F, Awouters, F, Niemegeers, C J, Schellekens, K H, Janssen, P A

“…Rats that had received 3% alcohol, 0.01% cocaine, or 0.002% fentanyl as the only beverage over 10 days showed marked preference for the drug solution when…”
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Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598) by Megens, A A, Awouters, F H, Meert, T F, Schellekens, K H, Niemegeers, C J, Janssen, P A

“…Ocaperidone, a new benzisoxazolyl piperidine neuroleptic, was compared with haloperidol, risperidone and ritanserin in a large series of pharmacological tests…”
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Oxatomide, a new orally active drug which inhibits both the release and the effects of allergic mediators by Awouters, F, Niemegeers, C J, Van den Berk, J, Van Neuten, J M, Lenaerts, F M, Borgers, M, Schellekens, K H, Broeckaert, A, De Cree, J, Janssen, P A

“…Oxatomide is a new potent inhibitor of anaphylactic and allergic reactions. After oral administration, the compound both inhibits the release of endogenous…”
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Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? by Janssen, P A, Niemegeers, C J, Schellekens, K H

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Etomidate, R-(+)-ethyl-1-( -methyl-benzyl)imidazole-5-carboxylate (R 16659), a potent, short-acting and relatively atoxic intravenous hypnotic agent in rats by Janssen, P A, Niemegeers, C J, Schellekens, K H, Lenaerts, F M

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IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTIC DRUGS (MAJOR TRANQUILLIZERS) FROM ANIMAL DATA?I. "NEUROLEPTIC ACTIVITY SPECTRA" FOR RATS by JANSSEN, P A, NIEMEGEERS, C J, SCHELLEKENS, K H

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Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats by Janssen, P A, Niemegeers, C J, Schellekens, K H, Lenaerts, F M

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Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone. III. Duration of antiemetic action and oral effectiveness of Haloperidol (R 1625) and of chlorpromazine in dogs by JANSSEN, P A, NIEMEGEERS, C J, SCHELLEKENS, K H

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Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine by Janssen, P A, Niemegeers, C J, Schellekens, K H, Dresse, A, Lenaerts, F M, Pinchard, A, Schaper, W K, van Nueten, J M, Verbruggen, F J

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The pharmacology of dehydrobenzperidol, a new potent and short acting neuroleptic agent chemically related to Haloperidol by JANSSEN, P A, NIEMEGEERS, C J, SCHELLEKENS, K H, VERBRUGGEN, F J, VAN NUETEN, J M

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Benzetimide and its optical isomers by Janssen, P A, Niemegeers, C J, Schellekens, K H, Demoen, P, Lenaerts, F M, Van Nueten, J M, Van Wijngaarden, I, Brugmans, J

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The pharmacology of penfluridol (R 16341) a new potent and orally long-acting neuroleptic drug by Janssen, P A, Niemegeers, C J, Schellekens, K H, Lenaerts, F M, Verbruggen, F J, Van Nueten, J M, Schaper, W K

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The pharmacology of fluspirilene (R 6218), a potent, long-acting and injectable neuroleptic drug by Janssen, P A, Niemegeers, C J, Schellekens, K H, Lenaerts, F M, Verbruggen, F J, van Nueten, J M, Marsboom, R H, Hérin, V V, Schaper, W K

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Bezitramide (R 4845), a new potent and orally long-acting analgesic compound by Janssen, P A, Niemegeers, C J, Schellekens, K H, Marsboom, R H, Herin, V V, Amery, W K, Admiraal, P V, Bosker, J T, Crul, J F, Pearce, C, Zegveld, C

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Sufentanil, a very potent and extremely safe intravenous morphine-like compound in mice, rats and dogs by Niemegeers, C J, Schellekens, K H, Van Bever, W F, Janssen, P A

“…Sufentanil (R 30 730), N-[4-methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenylpropanamide, is a chemically novel, highly potent and extremely safe…”
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N-4-Substituted 1-(2-arylethyl)-4-piperidinyl-N-phenylpropanamides, a novel series of extremely potent analgesics with unusually high safety margin by Van Bever, W F, Niemegeers, C J, Schellekens, K H, Janssen, P A

“…The intravenous analgesic activity and toxicity of a novel series of N-[4-substituted 1-(2-arylethyl)-4-piperidinyl]-N-phenylpropanamides was studied in rats…”
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Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone. IV. Influence of haloperidol (R 1625) and of chlorpromazine on the behaviour of rats in an unfamiliar "open field" situation by JANSSEN, P A, JAGENEAU, A H, SCHELLEKENS, K H

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The antiemetic effects of domperidone, a novel potent gastrokinetic by Niemegeers, C J, Schellekens, K H, Janssen, P A

“…Domperidone is the prototype of a new chemical class of compounds with potent gastrokinetic properties. The present study reports on the antiemetic activity…”
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