Search Results - "Scheld, Michael"

2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis by Tunkel, Allan R, Hasbun, Rodrigo, Bhimraj, Adarsh, Byers, Karin, Kaplan, Sheldon L, Michael Scheld, W, van de Beek, Diederik, Bleck, Thomas P, Garton, Hugh J L, Zunt, Joseph R

“…The Infectious Diseases Society of America (IDSA) Standards and Practice Guidelines Committee collaborated with partner organizations to convene a panel of 10…”
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Evidence of Archaeal Methanogens in Brain Abscess by Drancourt, Michel, Nkamga, Vanessa Demonfort, Lakhe, Ndèye Aïssatou, Régis, Jean-Marie, Dufour, Henry, Fournier, Pierre-Edouard, Bechah, Yassina, Scheld, W. Michael, Raoult, Didier

“…Background. Methanogens are antibiotic-resistant anaerobic archaea that escape routine detection in clinical microbiology. We hypothesized that methanogens are…”
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Rising rates of injection drug use associated infective endocarditis in Virginia with missed opportunities for addiction treatment referral: a retrospective cohort study by Gray, Megan E, Rogawski McQuade, Elizabeth T, Scheld, W Michael, Dillingham, Rebecca A

“…Injection drug use (IDU) is a growing public health threat in Virginia, though there is limited knowledge of related morbidity. The purpose of this study was…”
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Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis by Das, Rituparna, Koo, Mi-Sun, Kim, Bae Hoon, Jacob, Shevin T., Subbian, Selvakumar, Yao, Jie, Leng, Lin, Levy, Rebecca, Murchison, Charles, Burman, William J., Moore, Christopher C., Scheld, W. Michael, David, John R., Kaplan, Gilla, MacMicking, John D., Bucala, Richard

“…Macrophage migration inhibitory factor (MIF), an innate cytokine encoded in a functionally polymorphic genetic locus, contributes to detrimental inflammation…”
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The Management of Encephalitis: Clinical Practice Guidelines by the Infectious Diseases Society of America by Tunkel, Allan R., Glaser, Carol A., Bloch, Karen C., Sejvar, James J., Marra, Christina M., Roos, Karen L., Hartman, Barry J., Kaplan, Sheldon L., Scheld, W. Michael, Whitley, Richard J.

“…Guidelines for the diagnosis and treatment of patients with encephalitis were prepared by an Expert Panel of the Infectious Diseases Society of America. The…”
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Molecular dissection of an outbreak of carbapenem-resistant enterobacteriaceae reveals Intergenus KPC carbapenemase transmission through a promiscuous plasmid by Mathers, Amy J, Cox, Heather L, Kitchel, Brandon, Bonatti, Hugo, Brassinga, Ann Karen C, Carroll, Joanne, Scheld, W Michael, Hazen, Kevin C, Sifri, Costi D

“…Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as major causes of health care-associated infections worldwide. This diverse collection of organisms…”
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The Expansion of the Microbiological Spectrum of Brain Abscesses with Use of Multiple 16S Ribosomal DNA Sequencing by Raoultm, Didier, Masalma, Mouhamad Al, Armougom, Fabrice, Scheld, W. Michael, Dufour, Henri, Roche, Pierre-Hugues, Drancourt, Michel

“…Background. Brain abscess is commonly treated using empirically prescribed antibiotics. Thus, a comprehensive study of bacterial organisms associated with…”
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Practice Guidelines for the Management of Bacterial Meningitis by Tunkel, Allan R., Hartman, Barry J., Kaplan, Sheldon L., Kaufman, Bruce A., Roos, Karen L., Scheld, W. Michael, Whitley, Richard J.

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A Young Adult from the Middle East with Septic Shock, Pancytopenia, and Systolic Dysfunction by Vavolizza, Rick D, Alkabab, Yosra M, Scheld, W Michael, Mihalek, Andrew D

“…Pertinent laboratory data obtained on presentation Value on Presentation Reference Range Complete metabolic panel  Sodium, mmol/L 129 136–145  Potassium,…”
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The 10 X '20 Initiative: Pursuing a Global Commitment to Develop 10 New Antibacterial Drugs by 2020

“…The time has come for a global commitment to develop new antibacterial drugs. Current data document the impending disaster due to the confluence of decreasing…”
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Pathophysiology of Bacterial Meningitis: Mechanism(s) of Neuronal Injury by Scheld, W. Michael, Koedel, Uwe, Nathan, Barnett, Pfister, Hans-Walter

“…No bacterial disease has undergone a more dramatic change in epidemiology during the past decade than acute bacterial meningitis. This review describes the…”
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Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population by Jacob, Shevin T, Moore, Christopher C, Banura, Patrick, Pinkerton, Relana, Meya, David, Opendi, Pius, Reynolds, Steven J, Kenya-Mugisha, Nathan, Mayanja-Kizza, Harriet, Scheld, W Michael

“…Sepsis likely contributes to the high burden of infectious disease morbidity and mortality in low income countries. Data regarding sepsis management in…”
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Maintaining fluoroquinolone class efficacy: review of influencing factors by Scheld, W Michael

“…Previous experience with antimicrobial resistance has emphasized the importance of appropriate stewardship of these pharmacotherapeutic agents. The…”
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Antimicrobial Agents for Complicated Skin and Skin-Structure Infections: Justification of Noninferiority Margins in the Absence of Placebo-Controlled Trials by Spellberg, Brad, Talbot, George H., Boucher, Helen W., Bradley, John S., Gilbert, David, Scheld, W. Michael, Edwards, John, Bartlett, John G.

“…Background. The United States Food and Drug Administration requires clinical trial noninferiority margins to preserve a fraction (eg, 50%) of the established…”
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Derivation and validation of a universal vital assessment (UVA) score: a tool for predicting mortality in adult hospitalised patients in sub-Saharan Africa by Moore, Christopher C, Hazard, Riley, Saulters, Kacie J, Ainsworth, John, Adakun, Susan A, Amir, Abdallah, Andrews, Ben, Auma, Mary, Baker, Tim, Banura, Patrick, Crump, John A, Grobusch, Martin P, Huson, Michaëla A M, Jacob, Shevin T, Jarrett, Olamide D, Kellett, John, Lakhi, Shabir, Majwala, Albert, Opio, Martin, Rubach, Matthew P, Rylance, Jamie, Michael Scheld, W, Schieffelin, John, Ssekitoleko, Richard, Wheeler, India, Barnes, Laura E

“…BackgroundCritical illness is a leading cause of morbidity and mortality in sub-Saharan Africa (SSA). Identifying patients with the highest risk of death could…”
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Toll-like receptor 4 stimulation before or after Streptococcus pneumoniae induced sepsis improves survival and is dependent on T-cells by Musie, Edgar, Moore, Christopher C, Martin, Edward N, Scheld, W Michael

“…Endotoxin tolerance improves outcomes from gram negative sepsis but the underlying mechanism is not known. We determined if endotoxin tolerance before or after…”
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Cyclic AMP‐dependent inhibition of human neutrophil oxidative activity by substituted 2‐propynylcyclohexyl adenosine A2A receptor agonists by Sullivan, Gail W, Rieger, Jayson M, Michael Scheld, W, Macdonald, Timothy L, Linden, Joel

“…Novel 2‐propynylcyclohexyl‐5′‐N‐ehtylcarboxamidoadenosines, trans‐substituted in the 4‐position of the cyclohexyl ring, were evaluated in binding assays to the…”
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A Randomized and Blinded Multicenter Trial of High-Dose Fluconazole plus Placebo versus Fluconazole plus Amphotericin B as Therapy for Candidemia and Its Consequences in Nonneutropenic Subjects by Rex, John H., Pappas, Peter G., Karchmer, Adolf W., Sobel, Jack, Edwards, John E., Hadley, Susan, Brass, Corstiaan, Vazquez, Jose A., Chapman, Stanley W., Horowitz, Harold W., Zervos, Marcus, McKinsey, David, Lee, Jeannette, Babinchak, Timothy, Bradsher, Robert W., Cleary, John D., Cohen, David M., Danziger, Larry, Goldman, Mitchell, Goodman, Jesse, Hilton, Eileen, Hyslop, Newton E., Kett, Daniel H., Lutz, Jon, Rubin, Robert H., Scheld, W. Michael, Schuster, Mindy, Simmons, Bryan, Stein, David K., Washburn, Ronald G., Mautner, Linda, Chu, Teng-Chiao, Panzer, Helene, Rosenstein, Rebecca B., Booth, Jenia

“…A randomized, blinded, multicenter trial was conducted to compare fluconazole (800 mg per day) plus placebo with fluconazole plus amphotericin B (AmB)…”
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Bad Bugs Need Drugs: An Update on the Development Pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America by Talbot, George H., Bradley, John, Edwards, John E., Gilbert, David, Scheld, Michael, Bartlett, John G.

“…The Antimicrobial Availability Task Force (AATF) of the Infectious Diseases Society of America (IDSA) has viewed with concern the decreasing investment by…”
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Disseminated strongyloidiasis complicating glioblastoma therapy: a case report by Aregawi, Dawit, Lopez, David, Wick, Mark, Scheld, W. Michael, Schiff, David

“…Strongyloides stercoralis is an intestinal parasite that can cause fatal opportunistic infections in immunocompromised patients. Here we report an…”
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