Search Results - "Scheidmann, Manuel C."

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding by Gkountela, Sofia, Castro-Giner, Francesc, Szczerba, Barbara Maria, Vetter, Marcus, Landin, Julia, Scherrer, Ramona, Krol, Ilona, Scheidmann, Manuel C., Beisel, Christian, Stirnimann, Christian U., Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Aceto, Nicola

“…The ability of circulating tumor cells (CTCs) to form clusters has been linked to increased metastatic potential. Yet biological features and vulnerabilities…”
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MyCTC chip: microfluidic-based drug screen with patient-derived tumour cells from liquid biopsies by Schwab, Fabienne D., Scheidmann, Manuel C., Ozimski, Lauren L., Kling, André, Armbrecht, Lucas, Ryser, Till, Krol, Ilona, Strittmatter, Karin, Nguyen-Sträuli, Bich Doan, Jacob, Francis, Fedier, André, Heinzelmann-Schwarz, Viola, Wicki, Andreas, Dittrich, Petra S., Aceto, Nicola

“…Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment…”
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Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis by Castro-Giner, Francesc, Scheidmann, Manuel C, Aceto, Nicola

“…Circulating tumor cells (CTCs) are defined as those cells that detach from a cancerous lesion and enter the bloodstream. While generally most CTCs are…”
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Neutrophils escort circulating tumour cells to enable cell cycle progression by Szczerba, Barbara Maria, Castro-Giner, Francesc, Vetter, Marcus, Krol, Ilona, Gkountela, Sofia, Landin, Julia, Scheidmann, Manuel C., Donato, Cinzia, Scherrer, Ramona, Singer, Jochen, Beisel, Christian, Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Beerenwinkel, Niko, Aceto, Nicola

“…A better understanding of the features that define the interaction between cancer cells and immune cells is important for the development of new cancer…”
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An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression by Scheidmann, Manuel C, Castro-Giner, Francesc, Strittmatter, Karin, Krol, Ilona, Paasinen-Sohns, Aino, Scherrer, Ramona, Donato, Cinzia, Gkountela, Sofia, Szczerba, Barbara M, Diamantopoulou, Zoi, Muenst, Simone, Vlajnic, Tatjana, Kunz, Leo, Vetter, Marcus, Rochlitz, Christoph, Taylor, Verdon, Giachino, Claudio, Schroeder, Timm, Platt, Randall J, Aceto, Nicola

“…Blood-borne metastasis of breast cancer involves a series of tightly regulated sequential steps, including the growth of a primary tumor lesion, intravasation…”
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Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment by Donato, Cinzia, Szczerba, Barbara M, Scheidmann, Manuel C, Castro-Giner, Francesc, Aceto, Nicola

“…Blood-borne metastasis accounts for most cancer-related deaths and involves circulating tumor cells (CTCs) that are successful in establishing new tumors at…”
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Modularized CRISPR/dCas9 Effector Toolkit for Target-Specific Gene Regulation by Agne, Michael, Blank, Ilona, Emhardt, Alica J, Gäbelein, Christoph G, Gawlas, Fenja, Gillich, Nadine, Gonschorek, Patrick, Juretschke, Thomas J, Krämer, Stefan D, Louis, Natalie, Müller, Anne, Rudorf, Alina, Schäfer, Lisa M, Scheidmann, Manuel C, Schmunk, Lisa J, Schwenk, Philipp M, Stammnitz, Maximilian R, Warmer, Philipp M, Weber, Wilfried, Fischer, Adrian, Kaufmann, Beate, Wagner, Hanna J, Radziwill, Gerald

“…The ability to control mammalian genes in a synergistic mode using synthetic transcription factors is highly desirable in fields of tissue engineering, stem…”
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