Search Results - "Scheidereit, C"

High expression of RelA/p65 is associated with activation of nuclear factor-κB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis by WEICHERT, W, BOEHM, M, NIESPOREK, S, JACOB, J, DIETEL, M, SCHEIDEREIT, C, KRISTIANSEN, G, GEKELER, V, BAHRA, M, LANGREHR, J, NEUHAUS, P, DENKERT, C, IMRE, G, WELLER, C, HOFMANN, H.-P

“…Activation of nuclear factor- κ B (NF- κ B) signaling was observed in pancreatic adenocarcinoma cell lines and tumours. However, information on the expression…”
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Activation of NF‐kappa B in vivo is regulated by multiple phosphorylations by Naumann, M., Scheidereit, C.

“…The activation of nuclear factor kappa B (NF‐kappa B) in intact cells is mechanistically not well understood. Therefore we investigated the modifications…”
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Requirement of NF-κB/Rel for the development of hair follicles and other epidermal appendices by Schmidt-Ullrich, Ruth, Aebischer, Toni, Hülsken, Joerg, Birchmeier, Walter, Klemm, Uwe, Scheidereit, Claus

“…NF-κB/Rel transcription factors and IκB kinases (IKK) are essential for inflammation and immune responses, but also for bone-morphogenesis, skin proliferation…”
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Transcription factor NF-κB is constitutively activated in acute lymphoblastic leukemia cells by KORDES, U, KRAPPMANN, D, HEISSMEYER, V, LUDWIG, W. D, SCHEIDEREIT, C

“…The pleiotropic transcription factor NF-κB controls cellular apoptotic and growth processes and increasing evidence suggests a role in tumorigenesis. We…”
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Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-κB and induces tissue factor and PAI-1 expression : A potential link to accelerated arteriosclerosis by DECHEND, R, MAASS, M, GIEFFERS, J, DIETZ, R, SCHEIDEREIT, C, LEUTZ, A, GULBA, D. C

“…Background —Recent reports link C. pneumoniae infection of arteriosclerotic lesions to the precipitation of acute coronary syndromes, which also feature tissue…”
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The NF-κB/Rel and IκB gene families : mediators of immune response and inflammation by WULCZYN, F. G, KRAPPMANN, D, SCHEIDEREIT, C

“…Two families of gene regulators play an important role in cellular signaling processes in vertebrates: the nuclear factor kappa B (NF-kappa B)/Rel group of…”
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B-Cell Receptor- and Phorbol Ester-Induced NF-κB and c-Jun N-Terminal Kinase Activation in B Cells Requires Novel Protein Kinase C's by Krappmann, Daniel, Patke, Alina, Heissmeyer, Vigo, Scheidereit, Claus

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Aspirin inhibits NF-kappaB and protects from angiotensin II-induced organ damage by Muller, D N, Heissmeyer, V, Dechend, R, Hampich, F, Park, J K, Fiebeler, A, Shagdarsuren, E, Theuer, J, Elger, M, Pilz, B, Breu, V, Schroer, K, Ganten, D, Dietz, R, Haller, H, Scheidereit, C, Luft, F C

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High-Level Nuclear NF-κB and Oct-2 Is a Common Feature of Cultured Hodgkin/Reed-Sternberg Cells by Bargou, Ralf C., Leng, Corinna, Krappmann, Daniel, Emmerich, Florian, Mapara, Markus Y., Bommert, Kurt, Royer, Hans-Dieter, Scheidereit, Claus, Dorken, Bemd

“…There is a considerable lack of understanding about the common molecular defects that form the basis for the occurrence of Hodgkin's lymphoma. Despite a number…”
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In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-κB activity by WUCHTER, C, KRAPPMANN, D, CAI, Z, RUPPERT, V, SCHEIDEREIT, C, DÖRKEN, B, LUDWIG, W-D, KARAWAJEW, L

“…The TNF-related apoptosis-inducing ligand (TRAIL) is currently under evaluation as a possible (co-)therapeutic in cancer treatment. We therefore examined 129…”
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The pathogenetic significance of deregulated signal transduction pathways in Hodgkin's disease: the NF-kappaB-AP-1 network by Scheidereit, C

“…In the recent years, progress has been made in defining the lineage origin of malignant cells of Hodgkin's disease. The use of single cell PCR analysis and of…”
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Identification and Purification of a Human Immunoglobulin-Enhancer-Binding Protein (NF-κ B) that Activates Transcription from a Human Immunodeficiency Virus Type 1 Promoter in vitro by Kawakami, Kiyoshi, Scheidereit, Claus, Roeder, Robert G.

“…The enhancer-binding factor NF-κ B, which is found only in cells that transcribe immunoglobulin light chain genes, has been purified from nuclear extracts of…”
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The NF‐kappa B precursor p105 and the proto‐oncogene product Bcl‐3 are I kappa B molecules and control nuclear translocation of NF‐kappa B by Naumann, M., Wulczyn, F.G., Scheidereit, C.

“…We have examined the interaction of the NF‐kappa B precursor p105 with NF‐kappa B subunits. Similar to an I kappa B molecule, p105 associates in the cytoplasm…”
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The Ankyrin Repeat Domains of the NF-κB Precursor p105 and the Protooncogene bcl-3 Act as Specific Inhibitors of NF-κB DNA Binding by Hatada, Eunice N., Nieters, Alexandra, Wulczyn, F. Gregory, Naumann, Michael, Meyer, Ralf, Nucifora, Giuseppina, McKeithan, Timothy W., Scheidereit, Claus

“…The inducible pleiotropic transcription factor NF-κ B is composed of two subunits, p50 and p65. The p50 subunit is encoded on the N-terminal half of a 105-kDa…”
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Contacts between Hormone Receptor and DNA Double Helix within a Glucocorticoid Regulatory Element of Mouse Mammary Tumor Virus by Scheidereit, Claus, Beato, Miguel

“…Glucocorticoid hormones enhance the transcription of mouse mammary tumor virus DNA by mechanisms involving a direct interaction of the hormone receptor with…”
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Common structural constituents confer I kappa B activity to NF‐kappa B p105 and I kappa B/MAD‐3 by Hatada, E.N., Naumann, M., Scheidereit, C.

“…The vertebrate NF‐kappa B/c‐rel inhibitors MAD‐3/I kappa B alpha, I kappa B gamma/pdI and bcl‐3 all share a conserved ankyrin repeat domain (ARD) consisting of…”
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Cloning of the DNA-Binding Subunit of Human Nuclear Factor κB: The Level of its mRNA is Strongly Regulated by Phorbol Ester or Tumor Necrosis Factor α by Meyer, Ralf, Hatada, Eunice N., Hohmann, Hans-Peter, Haiker, Monika, Bartsch, Cornelia, Rothlisberger, Urs, Lahm, Hans-Werner, Schlaeger, Ernst J., Adolphus P. G. M. van Loon, Scheidereit, Claus

“…The DNA binding subunit of nuclear factor κ B (NF-κ B), a B-cell protein that interacts with the immunoglobulin κ light-chain gene enhancer, has been purified…”
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Maintenance of NF-kappa B activity is dependent on protein synthesis and the continuous presence of external stimuli by HOHMANN, H.-P, REMY, R, SCHEIDEREIT, C, VAN LOON, A. P. G. M

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Requirement of Hsp90 activity for IκB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κB activation by BROEMER, Meike, KRAPPMANN, Daniel, SCHEIDEREIT, Claus

“…The molecular chaperone Hsp90 affects the function and fate of a number of signaling molecules. We have investigated the Hsp90 requirement for constitutive and…”
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A pervasive role of ubiquitin conjugation in activation and termination of IκB kinase pathways by Krappmann, Daniel, Scheidereit, Claus

“…The nuclear factor (NF)‐κB pathway is a paradigm for gene expression control by ubiquitin‐mediated protein degradation. In stimulated cells, phosphorylation by…”
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