Search Results - "Scheibe, Marion"
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Proteotranscriptomics assisted gene annotation and spatial proteomics of Bombyx mori BmN4 cell line
Published in BMC genomics (06-10-2020)“…The process of identifying all coding regions in a genome is crucial for any study at the level of molecular biology, ranging from single-gene cloning to…”
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Quantitative Proteomics to Identify Nuclear RNA-Binding Proteins of Malat1
Published in International journal of molecular sciences (10-02-2020)“…The long non-coding RNA Malat1 has been implicated in several human cancers, while the mechanism of action is not completely understood. As RNAs in cells…”
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Correction to: Proteotranscriptomics assisted gene annotation and spatial proteomics of Bombyx mori BmN4 cell line
Published in BMC genomics (12-11-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators
Published in Genome research (01-12-2013)“…Telomeres are actively transcribed into telomeric repeat-containing RNA (TERRA), which has been implicated in the regulation of telomere length and…”
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Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus
Published in Nature communications (14-09-2024)“…Cell-cell junctions, and specifically desmosomes, are crucial for robust intercellular adhesion. Desmosomal function is compromised in the autoimmune…”
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The RNA fold interactome of evolutionary conserved RNA structures in S. cerevisiae
Published in Nature communications (03-06-2020)“…RNA-binding proteins play key roles in regulation of gene expression via recognition of structural features in RNA molecules. Here we apply a quantitative RNA…”
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PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells
Published in RNA (Cambridge) (01-01-2021)“…© 2021 Viceconte et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society. This article is distributed exclusively by the RNA Society for…”
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Unbiased RNA-protein interaction screen by quantitative proteomics
Published in Proceedings of the National Academy of Sciences - PNAS (30-06-2009)“…Mass spectrometry (MS)-based quantitative interaction proteomics has successfully elucidated specific protein-protein, DNA-protein, and small molecule-protein…”
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Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding
Published in PLoS genetics (01-09-2012)“…A causative role for single nucleotide polymorphisms (SNPs) in many genetic disorders has become evident through numerous genome-wide association studies…”
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Quantitative mass spectrometry and PAR-CLIP to identify RNA-protein interactions
Published in Nucleic acids research (01-10-2012)“…Systematic analysis of the RNA-protein interactome requires robust and scalable methods. We here show the combination of two completely orthogonal, generic…”
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Reader interactome of epigenetic histone marks in birds
Published in Proteomics (Weinheim) (01-02-2016)“…Lysine methylation is part of the posttranscriptional histone code employed to recruit modification specific readers to chromatin. Unbiased, quantitative mass…”
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Identification of Pri-miRNA Stem-Loop Interacting Proteins in Plants Using a Modified Version of the Csy4 CRISPR Endonuclease
Published in International journal of molecular sciences (11-08-2022)“…Regulation at the RNA level by RNA-binding proteins (RBPs) and microRNAs (miRNAs) is key to coordinating eukaryotic gene expression. In plants, the importance…”
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The nucleolar DExD/H protein Hel66 is involved in ribosome biogenesis in Trypanosoma brucei
Published in Scientific reports (15-09-2021)“…The biosynthesis of ribosomes is a complex cellular process involving ribosomal RNA, ribosomal proteins and several further trans-acting factors. DExD/H box…”
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Phylointeractomics reconstructs functional evolution of protein binding
Published in Nature communications (08-02-2017)“…Molecular phylogenomics investigates evolutionary relationships based on genomic data. However, despite genomic sequence conservation, changes in protein…”
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Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae
Published in Genome research (01-06-2013)“…A growing body of evidence supports the existence of an extensive network of RNA-binding proteins (RBPs) whose combinatorial binding affects the…”
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HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment
Published in The EMBO journal (12-06-2013)“…Telomeres are repetitive DNA structures that, together with the shelterin and the CST complex, protect the ends of chromosomes. Telomere shortening is…”
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DNA damage repair proteins across the Tree of Life
Published in iScience (16-06-2023)“…Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity…”
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A DNA methylation reader complex that enhances gene transcription
Published in Science (American Association for the Advancement of Science) (07-12-2018)“…DNA methylation generally functions as a repressive transcriptional signal, but it is also known to activate gene expression. In either case, the downstream…”
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Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
Published in The EMBO journal (15-02-2021)“…N6‐methyladenosine (m 6 A) regulates a variety of physiological processes through modulation of RNA metabolism. This modification is particularly enriched in…”
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Genome-wide Rules of Nucleosome Phasing in Drosophila
Published in Molecular cell (15-11-2018)“…Regular successions of positioned nucleosomes, or phased nucleosome arrays (PNAs), are predominantly known from transcriptional start sites (TSSs). It is…”
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