Search Results - "Scheibe, Daniel N"
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Structural Basis for the Autoinhibition and STI-571 Inhibition of c-Kit Tyrosine Kinase
Published in The Journal of biological chemistry (23-07-2004)“…The activity of the c-Kit receptor protein-tyrosine kinase is tightly regulated in normal cells, whereas deregulated c-Kit kinase activity is implicated in the…”
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Journal Article -
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Structures of the Cancer-Related Aurora-A, FAK, and EphA2 Protein Kinases from Nanovolume Crystallography
Published in Structure (London) (01-12-2002)“…Protein kinases are important drug targets in human cancers, inflammation, and metabolic diseases. This report presents the structures of kinase domains for…”
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Journal Article