Search Results - "Scheftner, William A."

Genomewide Significant Linkage to Recurrent, Early-Onset Major Depressive Disorder on Chromosome 15q by Holmans, Peter, Zubenko, George S., Crowe, Raymond R., DePaulo, J. Raymond, Scheftner, William A., Weissman, Myrna M., Zubenko, Wendy N., Boutelle, Sandra, Murphy-Eberenz, Kathleen, MacKinnon, Dean, McInnis, Melvin G., Marta, Diana H., Adams, Philip, Knowles, James A., Gladis, Madeleine, Thomas, Jo, Chellis, Jennifer, Miller, Erin, Levinson, Douglas F.

“…A genome scan was performed on the first phase sample of the Genetics of Recurrent Early-Onset Depression (GenRED) project. The sample consisted of 297…”
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Rare variants in neuronal excitability genes influence risk for bipolar disorder by Amenta, Seth A., Szelinger, Szabolcs, Glusman, Gustavo, Ashworth, Justin, Hou, Liping, Akula, Nirmala, Shekhtman, Tatyana, Badner, Judith A., Brunkow, Mary E., Mauldin, Denise E., Stittrich, Anna-Barbara, Rouleau, Katherine, Detera-Wadleigh, Sevilla D., Nurnberger, John I., Edenberg, Howard J., Gershon, Elliot S., Schork, Nicholas, Price, Nathan D., Gelinas, Richard, Hood, Leroy, Craig, David, McMahon, Francis J., Kelsoe, John R., Roach, Jared C.

“…We sequenced the genomes of 200 individuals from 41 families multiply affected with bipolar disorder (BD) to identify contributions of rare variants to genetic…”
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Mood Disorder Susceptibility Gene CACNA1C Modifies Mood-Related Behaviors in Mice and Interacts with Sex to Influence Behavior in Mice and Diagnosis in Humans by Dao, David T, Mahon, Pamela Belmonte, Cai, Xiang, Kovacsics, Colleen E, Blackwell, Robert A, Arad, Michal, Shi, Jianxin, Zandi, Peter P, O'Donnell, Patricio, Knowles, James A, Weissman, Myrna M, Coryell, William, Scheftner, William A, Lawson, William B, Levinson, Douglas F, Thompson, Scott M, Potash, James B, Gould, Todd D

“…Background Recent genome-wide association studies have associated polymorphisms in the gene CACNA1C , which codes for Cav 1.2, with a bipolar disorder and…”
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Genome-Wide Linkage and Follow-Up Association Study of Postpartum Mood Symptoms by Mahon, Pamela Belmonte, Payne, Jennifer L., MacKinnon, Dean F., Mondimore, Francis M., Goes, Fernando S., Schweizer, Barbara, Jancic, Dubravka, Coryell, William H., Holmans, Peter A., Shi, Jianxin, Knowles, James A., Scheftner, William A., Weissman, Myrna M., Levinson, Douglas F., DePaulo, J. Raymond, Zandi, Peter P., Potash, James B.

“…Objective: Family studies have suggested that postpartum mood symptoms might have a partly genetic etiology. The authors used a genome-wide linkage analysis to…”
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Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes by Smith, Erin N, Koller, Daniel L, Panganiban, Corrie, Szelinger, Szabolcs, Zhang, Peng, Badner, Judith A, Barrett, Thomas B, Berrettini, Wade H, Bloss, Cinnamon S, Byerley, William, Coryell, William, Edenberg, Howard J, Foroud, Tatiana, Gershon, Elliot S, Greenwood, Tiffany A, Guo, Yiran, Hipolito, Maria, Keating, Brendan J, Lawson, William B, Liu, Chunyu, Mahon, Pamela B, McInnis, Melvin G, McMahon, Francis J, McKinney, Rebecca, Murray, Sarah S, Nievergelt, Caroline M, Nurnberger, Jr, John I, Nwulia, Evaristus A, Potash, James B, Rice, John, Schulze, Thomas G, Scheftner, William A, Shilling, Paul D, Zandi, Peter P, Zöllner, Sebastian, Craig, David W, Schork, Nicholas J, Kelsoe, John R

“…Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants have been challenging to identify. We present new genotype data for…”
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Genetics of Recurrent Early-Onset Major Depression (GenRED): Final Genome Scan Report by Holmans, Peter, Weissman, Myrna M., Zubenko, George S., Scheftner, William A., Crowe, Raymond R., DePaulo, J. Raymond, Knowles, James A., Zubenko, Wendy N., Murphy-Eberenz, Kathleen, Marta, Diana H., Boutelle, Sandra, McInnis, Melvin G., Adams, Philip, Gladis, Madeline, Steele, Jo, Miller, Erin B., Potash, James B., MacKinnon, Dean F., Levinson, Douglas F.

“…Objective: The authors carried out a genomewide linkage scan to identify chromosomal regions likely to contain genes that contribute to susceptibility to…”
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Linkage Disequilibrium Mapping of a Chromosome 15q25-26 Major Depression Linkage Region and Sequencing of NTRK3 by Verma, Ranjana, Holmans, Peter, Knowles, James A, Grover, Deepak, Evgrafov, Oleg V, Crowe, Raymond R, Scheftner, William A, Weissman, Myrna M, DePaulo, J. Raymond, Potash, James B, Levinson, Douglas F

“…Background We reported genome-wide significant linkage on chromosome 15q25.3-26.2 to recurrent early-onset major depressive disorder (MDD-RE). Here we present…”
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Is perinatal depression familial? by Murphy-Eberenz, Kathleen, Zandi, Peter P., March, Dana, Crowe, Raymond R., Scheftner, William A., Alexander, Madeline, McInnis, Melvin G., Coryell, William, Adams, Philip, DePaulo, J. Raymond, Miller, Erin B., Marta, Diana H., Potash, James B., Payne, Jennifer, Levinson, Douglas F.

“…While major depressive disorder (MDD) is familial, it is not clear whether distinct familial-genetic factors influence vulnerability to depression during or…”
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Familial Aggregation of Illness Chronicity in Recurrent, Early-Onset Major Depression Pedigrees by Mondimore, Francis M., Zandi, Peter P., MacKinnon, Dean F., McInnis, Melvin G., Miller, Erin B., Crowe, Raymond P., Scheftner, William A., Marta, Diana H., Weissman, Myrna M., Levinson, Douglas F., Murphy-Ebenez, Kathleen P., DePaulo, J. Raymond, Potash, James B.

“…Objective: The authors used a large sample collected for genetic studies to determine whether a chronic course of illness defines a familial clinical subtype…”
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Genetics of Recurrent Early-Onset Major Depression (GenRED): Significant Linkage on Chromosome 15q25-q26 After Fine Mapping With Single Nucleotide Polymorphism Markers by Levinson, Douglas F., Evgrafov, Oleg V., Knowles, James A., Potash, James B., Weissman, Myrna M., Scheftner, William A., DePaulo, J. Raymond, Crowe, Raymond R., Murphy-Eberenz, Kathleen, Marta, Diana H., McInnis, Melvin G., Adams, Philip, Gladis, Madeline, Miller, Erin B., Thomas, Jo, Holmans, Peter

“…Objective: The authors studied a dense map of single nucleotide polymorphism (SNP) DNA markers on chromosome 15q25-q26 to maximize the informativeness of…”
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Time-related predictors of suicide in major affective disorder by Fawcett, J, Scheftner, W A, Fogg, L, Clark, D C, Young, M A, Hedeker, D, Gibbons, R

“…The authors studied 954 psychiatric patients with major affective disorders and found that nine clinical features were associated with suicide. Six of…”
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A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity by Mondimore, Francis M, Zandi, Peter P, MacKinnon, Dean F, McInnis, Melvin G, Miller, Erin B, Schweizer, Barbara, Crowe, Raymond P, Scheftner, William A, Weissman, Myrna M, Levinson, Douglas F, DePaulo, J. Raymond, Potash, James B

“…Abstract Background The study of chronicity in the course of major depression has been complicated by varying definitions of this illness feature. Because…”
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Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression by Verma, Ranjana, Cutler, David J., Holmans, Peter, Knowles, James A., Crowe, Raymond R., Scheftner, William A., Weissman, Myrna M., DePaulo Jr, J. Raymond, Levinson, Douglas F., Potash, James B.

“…Recent evidence suggests a potential role for the p11 gene in conferring risk to depressive disorders. p11 has been shown to influence serotonergic…”
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Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees by Payne, Jennifer L., Klein, Sarah R., Zamoiski, Rachel B., Zandi, Peter P., Bienvenu, Oscar J., MacKinnon, Dean F., Mondimore, Francis M., Schweizer, Barbara, Swartz, Karen L., Crowe, Raymond P., Scheftner, William A., Weissman, Myrna M., Levinson, Douglas F., DePaulo, J. Raymond, Potash, James B.

“…We sought to determine whether premenstrual mood symptoms exhibit familial aggregation in bipolar disorder or major depression pedigrees. Two thousand eight…”
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Genome-wide association study identifies 30 loci associated with bipolar disorder by Forstner, Andreas J., Wang, Yunpeng, Steinberg, Stacy, Trzaskowski, Maciej, Byrne, Enda M., Abbott, Liam, Akil, Huda, Anjorin, Adebayo, Antilla, Verneri, Barchas, Jack D., Belliveau, Richard, Pedersen, Carsten Bøcker, Bøen, Erlend, Budde, Monika, Bunney, William, Churchhouse, Claire, Clarke, Toni-Kim, Craig, David W., Cruceanu, Cristiana, Czerski, Piotr M., de Jong, Simone, Dumont, Ashley, Fischer, Sascha B., Frisén, Louise, Garnham, Julie, Giambartolomei, Claudia, Pedersen, Marianne Giørtz, Goldstein, Jaqueline, Gordon, Scott D., Green, Melissa J., Grove, Jakob, Heilbronner, Urs, Herms, Stefan, Huckins, Laura, Johnson, Jessica S., Juréus, Anders, Kandaswamy, Radhika, Knowles, James A., Lavebratt, Catharina, Lawrence, Jacob, Lee, Phil H., Levy, Shawn E., Li, Jun Z., Lucae, Susanne, Maaser, Anna, Maier, Wolfgang, McCarroll, Steve, McKay, James D., Meng, Fan, Montgomery, Grant W., Mühleisen, Thomas W., Nguyen, Hoang, Nievergelt, Caroline M., O’Donovan, Claire, Loohuis, Loes M. Olde, Ori, Anil P. S., Ösby, Urban, Perlis, Roy H., Pfennig, Andrea, Potash, James B., Reif, Andreas, Reinbold, Céline S., Rivera, Margarita, Roussos, Panos, Ryu, Euijung, Sánchez-Mora, Cristina, Slaney, Claire, Steffens, Michael, Strauss, John S., Zhang, Peng, Adolfsson, Rolf, Agartz, Ingrid, Alda, Martin, Baune, Bernhard T., Berrettini, Wade H., Biernacka, Joanna M., Blackwood, Douglas H. R., Børglum, Anders D., Corvin, Aiden, Hauser, Joanna, Kahn, René S., Lewis, Cathryn M., Li, Qingqin S., Melle, Ingrid, Morken, Gunnar, O’Donovan, Michael C., Paciga, Sara A., Pato, Carlos, Ramos-Quiroga, Josep Antoni, Ribasés, Marta, Rouleau, Guy A., Schulze, Thomas G., Sullivan, Patrick F., Vaaler, Arne E., Vincent, John B., Nurnberger, John I., Wray, Naomi R., Cichon, Sven, Scott, Laura J., Andreassen, Ole A.

“…Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of…”
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Lithium Discontinuation and Subsequent Effectiveness by Coryell, William, Solomon, David, Leon, Andrew C., Akiskal, Hagop S., Keller, Martin B., Scheftner, William A., Mueller, Tim

“…OBJECTIVE: Several reports have raised concern that the discontinuation of lithium may result in treatment resistance following recurrence of affective…”
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A mega-analysis of genome-wide association studies for major depressive disorder by Ripke, Stephan, Wray, Naomi R, Lewis, Cathryn M, Hamilton, Steven P, Weissman, Myrna M, Breen, Gerome, Byrne, Enda M, Blackwood, Douglas H R, Boomsma, Dorret I, Cichon, Sven, Heath, Andrew C, Holsboer, Florian, Lucae, Susanne, Madden, Pamela A F, Martin, Nicholas G, McGuffin, Peter, Muglia, Pierandrea, Noethen, Markus M, Penninx, Brenda P, Pergadia, Michele L, Potash, James B, Rietschel, Marcella, Lin, Danyu, Müller-Myhsok, Bertram, Shi, Jianxin, Steinberg, Stacy, Grabe, Hans J, Lichtenstein, Paul, Magnusson, Patrik, Perlis, Roy H, Preisig, Martin, Smoller, Jordan W, Stefansson, Kari, Uher, Rudolf, Kutalik, Zoltan, Tansey, Katherine E, Teumer, Alexander, Viktorin, Alexander, Barnes, Michael R, Bettecken, Thomas, Binder, Elisabeth B, Breuer, René, Castro, Victor M, Churchill, Susanne E, Coryell, William H, Craddock, Nick, Craig, Ian W, Czamara, Darina, De Geus, Eco J, Degenhardt, Franziska, Farmer, Anne E, Fava, Maurizio, Frank, Josef, Gainer, Vivian S, Gallagher, Patience J, Gordon, Scott D, Goryachev, Sergey, Gross, Magdalena, Guipponi, Michel, Henders, Anjali K, Herms, Stefan, Hickie, Ian B, Hoefels, Susanne, Hoogendijk, Witte, Hottenga, Jouke Jan, Iosifescu, Dan V, Ising, Marcus, Jones, Ian, Jones, Lisa, Jung-Ying, Tzeng, Knowles, James A, Kohane, Isaac S, Kohli, Martin A, Korszun, Ania, Landen, Mikael, Lawson, William B, Lewis, Glyn, Macintyre, Donald, Maier, Wolfgang, Mattheisen, Manuel, McGrath, Patrick J, McIntosh, Andrew, McLean, Alan, Middeldorp, Christel M, Middleton, Lefkos, Montgomery, Grant M, Murphy, Shawn N, Nauck, Matthias, Nolen, Willem A, Nyholt, Dale R, O'Donovan, Michael, Oskarsson, Högni, Pedersen, Nancy, Scheftner, William A, Schulz, Andrea, Schulze, Thomas G, Shyn, Stanley I, Sigurdsson, Engilbert, Slager, Susan L, Smit, Johannes H

“…Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have met with limited success. We sought to increase statistical power to…”
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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 by Sklar, Pamela, Ripke, Stephan, Scott, Laura J, Andreassen, Ole A, Cichon, Sven, Craddock, Nick, Edenberg, Howard J, Nurnberger, John I, Rietschel, Marcella, Blackwood, Douglas, Corvin, Aiden, Flickinger, Matthew, Guan, Weihua, Mattingsdal, Morten, McQuillin, Andrew, Kwan, Phoenix, Wienker, Thomas F, Daly, Mark, Dudbridge, Frank, Holmans, Peter A, Lin, Danyu, Burmeister, Margit, Greenwood, Tiffany A, Hamshere, Marian L, Muglia, Pierandrea, Smith, Erin N, Zandi, Peter P, Nievergelt, Caroline M, McKinney, Rebecca, Shilling, Paul D, Schork, Nicholas J, Bloss, Cinnamon S, Foroud, Tatiana, Koller, Daniel L, Gershon, Elliot S, Liu, Chunyu, Badner, Judith A, Scheftner, William A, Lawson, William B, Nwulia, Evaristus A, Hipolito, Maria, Coryell, William, Rice, John, Byerley, William, McMahon, Francis J, Schulze, Thomas G, Berrettini, Wade, Lohoff, Falk W, Potash, James B, Mahon, Pamela B, McInnis, Melvin G, Zöllner, Sebastian, Zhang, Peng, Craig, David W, Szelinger, Szabocls, Barrett, Thomas B, Breuer, René, Meier, Sandra, Strohmaier, Jana, Witt, Stephanie H, Tozzi, Federica, Farmer, Anne, McGuffin, Peter, Strauss, John, Xu, Wei, Kennedy, James L, Vincent, John B, Matthews, Keith, Day, Richard, Ferreira, Manuel A, O'Dushlaine, Colm, Perlis, Roy, Raychaudhuri, Soumya, Ruderfer, Douglas, Lee, Phil H, Smoller, Jordan W, Li, Jun, Absher, Devin, Bunney, William E, Barchas, Jack D, Schatzberg, Alan F, Jones, Edward G, Meng, Fan, Thompson, Robert C, Watson, Stanley J, Myers, Richard M, Akil, Huda, Boehnke, Michael, Chambert, Kim, Moran, Jennifer, Scolnick, Ed, Djurovic, Srdjan, Melle, Ingrid, Morken, Gunnar, Gill, Michael, Morris, Derek, Quinn, Emma, Mühleisen, Thomas W, Degenhardt, Franziska A, Mattheisen, Manuel

“…We conducted a combined genome-wide association study (GWAS) of 7,481 individuals with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric…”
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Identification of pathways for bipolar disorder: a meta-analysis by Nurnberger, Jr, John I, Koller, Daniel L, Jung, Jeesun, Edenberg, Howard J, Foroud, Tatiana, Guella, Ilaria, Vawter, Marquis P, Kelsoe, John R

“…Genome-wide investigations provide systematic information regarding the neurobiology of psychiatric disorders. To identify biological pathways that contribute…”
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Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder by Hou, Liping, Bergen, Sarah E, Akula, Nirmala, Song, Jie, Hultman, Christina M, Landén, Mikael, Adli, Mazda, Alda, Martin, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Badner, Judith A, Barrett, Thomas B, Bauer, Michael, Baune, Bernhard T, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Berrettini, Wade H, Bhattacharjee, Abesh Kumar, Biernacka, Joanna M, Birner, Armin, Bloss, Cinnamon S, Brichant-Petitjean, Clara, Bui, Elise T, Byerley, William, Cervantes, Pablo, Chillotti, Caterina, Cichon, Sven, Colom, Francesc, Coryell, William, Craig, David W, Cruceanu, Cristiana, Czerski, Piotr M, Davis, Tony, Dayer, Alexandre, Degenhardt, Franziska, Del Zompo, Maria, DePaulo, J Raymond, Edenberg, Howard J, Étain, Bruno, Falkai, Peter, Foroud, Tatiana, Forstner, Andreas J, Frisén, Louise, Frye, Mark A, Fullerton, Janice M, Gard, Sébastien, Garnham, Julie S, Gershon, Elliot S, Goes, Fernando S, Greenwood, Tiffany A, Grigoroiu-Serbanescu, Maria, Hauser, Joanna, Heilbronner, Urs, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hipolito, Maria, Hitturlingappa, Shashi, Hoffmann, Per, Hofmann, Andrea, Jamain, Stephane, Jiménez, Esther, Kahn, Jean-Pierre, Kassem, Layla, Kelsoe, John R, Kittel-Schneider, Sarah, Kliwicki, Sebastian, Koller, Daniel L, König, Barbara, Lackner, Nina, Laje, Gonzalo, Lang, Maren, Lavebratt, Catharina, Lawson, William B, Leboyer, Marion, Leckband, Susan G, Liu, Chunyu, Maaser, Anna, Mahon, Pamela B, Maier, Wolfgang, Maj, Mario, Manchia, Mirko, Martinsson, Lina, McCarthy, Michael J, McElroy, Susan L, McInnis, Melvin G, McKinney, Rebecca, Mitchell, Philip B, Mitjans, Marina, Mondimore, Francis M, Monteleone, Palmiero, Mühleisen, Thomas W, Nievergelt, Caroline M, Nöthen, Markus M, Novák, Tomas, Nurnberger, Jr, John I, Nwulia, Evaristus A, Ösby, Urban

“…Bipolar disorder (BD) is a genetically complex mental illness characterized by severe oscillations of mood and behaviour. Genome-wide association studies…”
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