Search Results - "Scheer, Elisabeth"

The architecture of human general transcription factor TFIID core complex by Bieniossek, Christoph, Papai, Gabor, Schaffitzel, Christiane, Garzoni, Frederic, Chaillet, Maxime, Scheer, Elisabeth, Papadopoulos, Petros, Tora, Laszlo, Schultz, Patrick, Berger, Imre

“…The structures of three distinct human transcription factor IID (TFIID) protein assemblies are solved using cryo-electron microscopy; by incorporating TAF8 and…”
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KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification by Fournier, Marjorie, Orpinell, Meritxell, Grauffel, Cédric, Scheer, Elisabeth, Garnier, Jean-Marie, Ye, Tao, Chavant, Virginie, Joint, Mathilde, Esashi, Fumiko, Dejaegere, Annick, Gönczy, Pierre, Tora, László

“…Lysine acetylation is a widespread post-translational modification regulating various biological processes. To characterize cellular functions of the human…”
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Cytoplasmic TAF2–TAF8–TAF10 complex provides evidence for nuclear holo–TFIID assembly from preformed submodules by Trowitzsch, Simon, Viola, Cristina, Scheer, Elisabeth, Conic, Sascha, Chavant, Virginie, Fournier, Marjorie, Papai, Gabor, Ebong, Ima-Obong, Schaffitzel, Christiane, Zou, Juan, Haffke, Matthias, Rappsilber, Juri, Robinson, Carol V., Schultz, Patrick, Tora, Laszlo, Berger, Imre

“…General transcription factor TFIID is a cornerstone of RNA polymerase II transcription initiation in eukaryotic cells. How human TFIID—a megadalton-sized…”
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ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct by Yayli, Gizem, Bernardini, Andrea, Mendoza Sanchez, Paulina Karen, Scheer, Elisabeth, Damilot, Mylène, Essabri, Karim, Morlet, Bastien, Negroni, Luc, Vincent, Stéphane D., Timmers, H.T. Marc, Tora, László

“…To understand the function of multisubunit complexes, it is of key importance to uncover the precise mechanisms that guide their assembly. Nascent proteins can…”
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A dual role of linker histone H1.4 Lys 34 acetylation in transcriptional activation by Kamieniarz, Kinga, Izzo, Annalisa, Dundr, Miroslav, Tropberger, Philipp, Ozretic, Luka, Kirfel, Jutta, Scheer, Elisabeth, Tropel, Philippe, Wisniewski, Jacek R, Tora, Laszlo, Viville, Stephane, Buettner, Reinhard, Schneider, Robert

“…The linker histone H1 is a key player in chromatin organization, yet our understanding of the regulation of H1 functions by post-translational modifications is…”
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Gene-Specific Modulation of TAF10 Function by SET9-Mediated Methylation by Kouskouti, Antigone, Scheer, Elisabeth, Staub, Adrien, Tora, Làszlò, Talianidis, Iannis

“…SET9 is a member of the SET domain-containing histone methyltransferase family that can specifically methylate histone 3 at lysine 4 position. Although…”
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Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID by Gupta, Kapil, Watson, Aleksandra A, Baptista, Tiago, Scheer, Elisabeth, Chambers, Anna L, Koehler, Christine, Zou, Juan, Obong-Ebong, Ima, Kandiah, Eaazhisai, Temblador, Arturo, Round, Adam, Forest, Eric, Man, Petr, Bieniossek, Christoph, Laue, Ernest D, Lemke, Edward A, Rappsilber, Juri, Robinson, Carol V, Devys, Didier, Tora, Làszlò, Berger, Imre

“…General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising…”
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Chromatin interaction of TATA-binding protein is dynamically regulated in human cells by de Graaf, Petra, Mousson, Florence, Geverts, Bart, Scheer, Elisabeth, Tora, Laszlo, Houtsmuller, Adriaan B, Timmers, H. Th. Marc

“…Gene transcription in mammalian cells is a dynamic process involving regulated assembly of transcription complexes on chromatin in which the TATA-binding…”
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Identification of a small TAF complex and its role in the assembly of TAF-containing complexes by Demény, Màté A, Soutoglou, Evi, Nagy, Zita, Scheer, Elisabeth, Jànoshàzi, Agnes, Richardot, Magalie, Argentini, Manuela, Kessler, Pascal, Tora, Laszlo

“…TFIID plays a role in nucleating RNA polymerase II preinitiation complex assembly on protein-coding genes. TFIID is a multisubunit complex comprised of the…”
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TAF9b (Formerly TAF9L) Is a Bona Fide TAF That Has Unique and Overlapping Roles with TAF9 by Frontini, Mattia, Soutoglou, Evi, Argentini, Manuela, Bole-Feysot, Christine, Jost, Bernard, Scheer, Elisabeth, Tora, Laszlo

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Two Different Drosophila ADA2 Homologues Are Present in Distinct GCN5 Histone Acetyltransferase-Containing Complexes by Muratoglu, Selen, Georgieva, Sofia, Pápai, Gábor, Scheer, Elisabeth, Enünlü, Izzet, Komonyi, Orbán, Cserpán, Imre, Lebedeva, Lubov, Nabirochkina, Elena, Udvardy, Andor, Tora, László, Boros, Imre

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The Nuclear Import of TAF10 Is Regulated by One of Its Three Histone Fold Domain-Containing Interaction Partners by Soutoglou, Evi, Demény, Màté A., Scheer, Elisabeth, Fienga, Giulia, Sassone-Corsi, Paolo, Tora, Làszlò

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TAF10 (TAFII30) Is Necessary for TFIID Stability and Early Embryogenesis in Mice by Mohan, William S., Scheer, Elisabeth, Wendling, Olivia, Metzger, Daniel, Tora, Làszlò

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The human estrogen receptor has two independent nonacidic transcriptional activation functions by Tora, L, White, J, Brou, C, Tasset, D, Webster, N, Scheer, E, Chambon, P

“…We have previously reported the presence of a hormone-inducible transcriptional activation function (TAF-2) within the region of the estrogen receptor (ER)…”
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Distinct classes of transcriptional activating domains function by different mechanisms by Tasset, D, Tora, L, Fromental, C, Scheer, E, Chambon, P

“…We have previously shown that the two transcriptional activation functions (TAF-1 and TAF-2) of the human estrogen receptor (hER) have synergistic properties…”
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Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5 by Riss, Anne, Scheer, Elisabeth, Joint, Mathilde, Trowitzsch, Simon, Berger, Imre, Tora, László

“…Histone acetyl transferases (HATs) play a crucial role in eukaryotes by regulating chromatin architecture and locus specific transcription. GCN5 (KAT2A) is a…”
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Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID by Bernardini, Andrea, Mukherjee, Pooja, Scheer, Elisabeth, Kamenova, Ivanka, Antonova, Simona, Mendoza Sanchez, Paulina Karen, Yayli, Gizem, Morlet, Bastien, Timmers, H.T. Marc, Tora, László

“…Large heteromeric multiprotein complexes play pivotal roles at every step of gene expression in eukaryotic cells. Among them, the 20-subunit basal…”
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TAF8 regions important for TFIID lobe B assembly or for TAF2 interactions are required for embryonic stem cell survival by Scheer, Elisabeth, Luo, Jie, Bernardini, Andrea, Ruffenach, Frank, Garnier, Jean-Marie, Kolb-Cheynel, Isabelle, Gupta, Kapil, Berger, Imre, Ranish, Jeff, Tora, László

“…The human general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is…”
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Coactivators and general transcription factors have two distinct dynamic populations dependent on transcription by Vosnakis, Nikolaos, Koch, Marc, Scheer, Elisabeth, Kessler, Pascal, Mély, Yves, Didier, Pascal, Tora, László

“…SAGA and ATAC are two distinct chromatin modifying co‐activator complexes with distinct enzymatic activities involved in RNA polymerase II (Pol II)…”
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SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells by Fischer, Veronique, Hisler, Vincent, Scheer, Elisabeth, Lata, Elisabeth, Morlet, Bastien, Plassard, Damien, Helmlinger, Dominique, Devys, Didier, Tora, László, Vincent, Stéphane D

“…Abstract Coactivator complexes regulate chromatin accessibility and transcription. SAGA (Spt-Ada-Gcn5 Acetyltransferase) is an evolutionary conserved…”
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