Search Results - "Scheede, M"
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Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil
Published in Neuropharmacology (2001)“…The N-methyl-D-aspartate (NMDA) antagonist ifenprodil and several structurally related compounds are highly selective for the NR2B-containing receptor subtype…”
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Antinociception and (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid antagonism by gabapentin in the rat spinal cord in vivo
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2000)“…Gabapentin, a novel anticonvulsant and analgesic with an unknown mechanism of action, was tested on spinal dorsal horn neurone activity evoked by…”
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The N-methyl- d-aspartate antagonistic and opioid components of d-methadone antinociception in the rat spinal cord
Published in Neuroscience letters (22-12-2000)“…The d-enantiomer of the opioid methadone is a weak opioid with low micromolar affinity to the N-methyl- d-aspartate (NMDA) receptor. We have investigated the…”
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Modulation of spinal nociception by GluR5 kainate receptor ligands in acute and hyperalgesic states and the role of gabaergic mechanisms
Published in Neuropharmacology (01-09-2002)“…GluR5 receptors modulate spinal nociception, however, their role in nociceptive hypersensitivity remains unclear. Using behavioural and electrophysiological…”
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