Search Results - "Schedlich, Lynette J"

Molecular basis of the interaction between IGFBP-3 and retinoid X receptor: Role in modulation of RAR-signaling by Schedlich, Lynette J., Graham, Lloyd D., O’Han, Michelle K., Muthukaruppan, Anita, Yan, Xiaolang, Firth, Sue M., Baxter, Robert C.

“…IGFBP-3 interacts with the retinoid X receptor-α (RXRα) and retinoic acid receptor-α (RARα) and thereby interferes with the formation of RXR:RAR heterodimers…”
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TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells by Schedlich, Lynette J., Yenson, Vanessa M., Baxter, Robert C.

“…•TGF-β1 activates the Ras/Raf/MAPK pathway to stimulate cell cycle progression and proliferation.•TGF-β1-induced expression of IGFBP-3 opposes these effects by…”
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Role of insulin-like growth factor binding protein-3 in breast cancer cell growth by Schedlich, Lynette J., Graham, Lloyd D.

“…The mitogenic effects of insulin‐like growth factors (IGFs) are regulated by a family of insulin‐like growth factor binding proteins (IGFBPs). One member of…”
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Inhibition of adipocyte differentiation by insulin-like growth factor-binding protein-3 by Chan, Sophie S Y, Schedlich, Lynette J, Twigg, Stephen M, Baxter, Robert C

“…Insulin-like growth factor-binding protein-3 (IGFBP-3) interacts with the type II nuclear receptors retinoid X receptor (RXR)alpha and retinoic acid…”
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Insulin-Like Growth Factor Binding Protein-5 Interacts with the Vitamin D Receptor and Modulates the Vitamin D Response in Osteoblasts by Schedlich, Lynette J, Muthukaruppan, Anita, O’Han, Michelle K, Baxter, Robert C

“…The 1,25 dihydroxyvitamin D3 [1,25(OH)2D3]-induced differentiation of osteoblasts comprises the sequential induction of cell cycle arrest at G0/G1 and the…”
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Insulin-like Growth Factor-binding Protein (IGFBP)-3 and IGFBP-5 Share a Common Nuclear Transport Pathway in T47D Human Breast Carcinoma Cells by Schedlich, L J, Young, T F, Firth, S M, Baxter, R C

“…Insulin-like growth factor-binding proteins (IGFBPs) play an integral role in modifying insulin-like growth factor actions in a wide variety of cell types…”
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Effects of endogenous insulin-like growth factor binding protein-3 on cell cycle regulation in breast cancer cells by O'Han, Michelle K., Baxter, Robert C., Schedlich, Lynette J.

“…High tissue insulin-like growth factor binding protein-3 (IGFBP-3) expression in breast cancers is associated in some studies with rapid growth and poor…”
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Insulin-like growth factor binding protein-3 prevents retinoid receptor heterodimerization: implications for retinoic acid-sensitivity in human breast cancer cells by Schedlich, Lynette J, O’Han, Michelle K, Leong, Gary M, Baxter, Robert C

“…Insulin-like growth factor binding protein-3 (IGFBP-3) has both IGF-dependent and -independent effects on cell growth, which are frequently growth-inhibitory…”
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Phosphorylation of Insulin-Like Growth Factor Binding Protein-3 by Deoxyribonucleic Acid-Dependent Protein Kinase Reduces Ligand Binding and Enhances Nuclear Accumulation by Schedlich, Lynette J, Nilsen, Trine, John, Anna P, Jans, David A, Baxter, Robert C

“…The IGF binding proteins (IGFBPs) regulate the mitogenic effects of IGFs in the extracellular environment. Several members of this family, including IGFBP-3,…”
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Transcriptional activation of the human osteocalcin gene by basic fibroblast growth factor by Schedlich, Lynette J., Flanagan, Judith L., Crofts, Linda A., Gillies, Susan A., Goldberg, Daniella, Morrison, Nigel A., Eisman, John A.

“…Basic fibroblast growth factor (bFGF) has been detected in bone cells and stimulates osteoblast proliferation; however, its role in the regulation of bone…”
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Primary structure of a human glandular kallikrein gene by Schedlich, L J, Bennetts, B H, Morris, B J

“…To isolate a human glandular kallikrein gene, a human genomic library was screened with a probe made from a mouse kallikrein cDNA (pMK-1). Overlapping clones…”
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Nuclear Import of Insulin-like Growth Factor-binding Protein-3 and -5 Is Mediated by the Importin β Subunit by Schedlich, Lynette J., Le Page, Sophie L., Firth, Sue M., Briggs, Lyndall J., Jans, David A., Baxter, Robert C.

“…Although insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 are known to modulate cell growth by reversibly sequestering extracellular…”
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Kallikrein genes: cloning in man and expression in rat renal hypertension by Schedlich, L J, Catanzaro, D F, Morris, B J

“…Genes for the small human glandular kallikrein gene family were isolated. Members of this family include renal/pancreatic kallikrein, prostate-specific antigen…”
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P-33 IGF-INDEPENDENT EFFECTS OF IGFBP-3 IN BREAST CANCER CELLS AS DETERMINED BY RNA INTERFERENCE by O'Han, Michelle K, Schedlich, Lynette J, Baxter, Robert C

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Nuclear Import of Insulin-like Growth Factor-binding Protein-3 and -5 Is Mediated by the Importin β Subunit by Lynette J. Schedlich, Sophie L. Le Page, Sue M. Firth, Lyndall J. Briggs, David A. Jans, Robert C. Baxter

“…Although insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 are known to modulate cell growth by reversibly sequestering extracellular…”
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Antiproliferative and pro-apoptotic activities of insulin-like growth factor-binding protein-3 by Baxter, Robert C., Butt, Alison J., Schedlich, Lynette J., Martin, Janet L.

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Three Alu repeated sequences associated with a human glandular kallikrein gene by Schedlich, L J, Morris, B J

“…1. Recently the complete primary structure of a human glandular kallikrein gene, hGK-1, was reported. The present paper presents further structural…”
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