Search Results - "Scheck, Adrienne C"

The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma by Abdelwahab, Mohammed G, Fenton, Kathryn E, Preul, Mark C, Rho, Jong M, Lynch, Andrew, Stafford, Phillip, Scheck, Adrienne C

“…The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that alters metabolism by increasing the level of ketone bodies in the blood. KetoCal® (KC) is a…”
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The ketogenic diet for the treatment of malignant glioma by Woolf, Eric C., Scheck, Adrienne C.

“…Advances in our understanding of glioma biology has led to an increase in targeted therapies in preclinical and clinical trials; however, cellular…”
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Biomarkers of mitochondrial dysfunction in autism spectrum disorder: A systematic review and meta-analysis by Frye, Richard E., Rincon, Nicole, McCarty, Patrick J., Brister, Danielle, Scheck, Adrienne C., Rossignol, Daniel A.

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 1 in 36 children and is associated with physiological abnormalities, most notably…”
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Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy by Woolf, Eric C, Syed, Nelofer, Scheck, Adrienne C

“…Malignant brain tumors are devastating despite aggressive treatments such as surgical resection, chemotherapy and radiation therapy. The average life…”
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Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors by Hajji, Nabil, Garcia-Revilla, Juan, Soto, Manuel Sarmiento, Perryman, Richard, Symington, Jake, Quarles, Chad C, Healey, Deborah R, Guo, Yijie, Orta-Vázquez, Manuel Luis, Mateos-Cordero, Santiago, Shah, Khalid, Bomalaski, John, Anichini, Giulio, Tzakos, Andreas G, Crook, Timothy, O'Neill, Kevin, Scheck, Adrienne C, Venero, Jose Luis, Syed, Nelofer

“…New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the efficacy of radiotherapy for GBM is…”
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The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model by Woolf, Eric C, Curley, Kara L, Liu, Qingwei, Turner, Gregory H, Charlton, Julie A, Preul, Mark C, Scheck, Adrienne C

“…The successful treatment of malignant gliomas remains a challenge despite the current standard of care, which consists of surgery, radiation and temozolomide…”
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Bioenergetic signatures of neurodevelopmental regression by Frye, Richard E, McCarty, Patrick J, Werner, Brianna A, Rose, Shannon, Scheck, Adrienne C

“…Studies have linked autism spectrum disorder (ASD) to physiological abnormalities including mitochondrial dysfunction. Mitochondrial dysfunction may be linked…”
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Blood RNA Sequencing Indicates Upregulated BATF2 and LY6E and Downregulated ISG15 and MT2A Expression in Children with Autism Spectrum Disorder by Voinsky, Irena, Zoabi, Yazeed, Shomron, Noam, Harel, Moria, Cassuto, Hanoch, Tam, Joseph, Rose, Shannon, Scheck, Adrienne C., Karim, Mohammad A., Frye, Richard E., Aran, Adi, Gurwitz, David

“…Mutations in over 100 genes are implicated in autism spectrum disorder (ASD). DNA SNPs, CNVs, and epigenomic modifications also contribute to ASD…”
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A Network Model of a Cooperative Genetic Landscape in Brain Tumors by Bredel, Markus, Scholtens, Denise M, Harsh, Griffith R, Bredel, Claudia, Chandler, James P, Renfrow, Jaclyn J, Yadav, Ajay K, Vogel, Hannes, Scheck, Adrienne C, Tibshirani, Robert, Sikic, Branimir I

“…CONTEXT: Gliomas, particularly glioblastomas, are among the deadliest of human tumors. Gliomas emerge through the accumulation of recurrent chromosomal…”
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Mathematical Analysis of Glioma Growth in a Murine Model by Rutter, Erica M., Stepien, Tracy L., Anderies, Barrett J., Plasencia, Jonathan D., Woolf, Eric C., Scheck, Adrienne C., Turner, Gregory H., Liu, Qingwei, Frakes, David, Kodibagkar, Vikram, Kuang, Yang, Preul, Mark C., Kostelich, Eric J.

“…Five immunocompetent C57BL/6-cBrd/cBrd/Cr (albino C57BL/6) mice were injected with GL261-luc2 cells, a cell line sharing characteristics of human glioblastoma…”
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The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma by Stafford, Phillip, Abdelwahab, Mohammed G, Kim, Do Young, Preul, Mark C, Rho, Jong M, Scheck, Adrienne C

“…Malignant brain tumors affect people of all ages and are the second leading cause of cancer deaths in children. While current treatments are effective and…”
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Progress in Confocal Laser Endomicroscopy for Neurosurgery and Technical Nuances for Brain Tumor Imaging With Fluorescein by Belykh, Evgenii, Miller, Eric J, Carotenuto, Alessandro, Patel, Arpan A, Cavallo, Claudio, Martirosyan, Nikolay L, Healey, Debbie R, Byvaltsev, Vadim A, Scheck, Adrienne C, Lawton, Michael T, Eschbacher, Jennifer M, Nakaji, Peter, Preul, Mark C

“…Previous studies showed that confocal laser endomicroscopy (CLE) images of brain tumors acquired by a first-generation (Gen1) CLE system using fluorescein…”
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Potential application of a handheld confocal endomicroscope imaging system using a variety of fluorophores in experimental gliomas and normal brain by Martirosyan, Nikolay L, Georges, Joseph, Eschbacher, Jennifer M, Cavalcanti, Daniel D, Elhadi, Ali M, Abdelwahab, Mohammed G, Scheck, Adrienne C, Nakaji, Peter, Spetzler, Robert F, Preul, Mark C

“…The authors sought to assess the feasibility of a handheld visible-wavelength confocal endomicroscope imaging system (Optiscan 5.1, Optiscan Pty., Ltd.) using…”
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The ketogenic diet for the treatment of glioma: Insights from genetic profiling by Scheck, Adrienne C, Abdelwahab, Mohammed G, Fenton, Kathryn E, Stafford, Phillip

“…Summary Seizures, particularly first onset seizures in adults, are a diagnostic hallmark of brain tumors ( Giglio and Villano, 2010 ). Unfortunately, malignant…”
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Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age by Lee, Yohan, Scheck, Adrienne C, Cloughesy, Timothy F, Lai, Albert, Dong, Jun, Farooqi, Haumith K, Liau, Linda M, Horvath, Steve, Mischel, Paul S, Nelson, Stanley F

“…Glioblastomas are the most common primary brain tumour in adults. While the prognosis for patients is poor, gene expression profiling has detected signatures…”
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Cyclooxygenase-1 or -2--which one mediates lipopolysaccharide-induced hypothermia? by Steiner, Alexandre A, Hunter, John C, Phipps, Sean M, Nucci, Tatiane B, Oliveira, Daniela L, Roberts, Jennifer L, Scheck, Adrienne C, Simmons, Daniel L, Romanovsky, Andrej A

“…Systemic inflammation is associated with either fever or hypothermia. Fever, a response to mild systemic inflammation, is mediated by cyclooxygenase (COX)-2…”
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Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet by Lussier, Danielle M, Woolf, Eric C, Johnson, John L, Brooks, Kenneth S, Blattman, Joseph N, Scheck, Adrienne C

“…Glioblastoma multiforme is a highly aggressive brain tumor with a poor prognosis, and advances in treatment have led to only marginal increases in overall…”
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A phase 1 study of prexasertib (LY2606368), a CHK1/2 inhibitor, in pediatric patients with recurrent or refractory solid tumors, including CNS tumors: A report from the Children's Oncology Group Pediatric Early Phase Clinical Trials Network (ADVL1515) by Cash, Thomas, Fox, Elizabeth, Liu, Xiaowei, Minard, Charles G., Reid, Joel M., Scheck, Adrienne C., Weigel, Brenda J., Wetmore, Cynthia

“…Background Prexasertib (LY2606368) is a novel, second‐generation, selective dual inhibitor of checkpoint kinase proteins 1 (CHK1) and 2 (CHK2). We conducted a…”
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Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid–Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma by Belykh, Evgenii, Miller, Eric J., Hu, Danying, Martirosyan, Nikolay L., Woolf, Eric C., Scheck, Adrienne C., Byvaltsev, Vadim A., Nakaji, Peter, Nelson, Leonard Y., Seibel, Eric J., Preul, Mark C.

“…Fluorescence-guided surgery with protoporphyrin IX (PpIX) as a photodiagnostic marker is gaining acceptance for resection of malignant gliomas. Current…”
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Provision of rapid and specific ex vivo diagnosis of central nervous system lymphoma from rodent xenograft biopsies by a fluorescent aptamer by Georges, Joseph, Qi, Xiaodong, Liu, Xiaowei, Zhou, Yu, Woolf, Eric C, Valeri, Amber, Al-Atrache, Zein, Belykh, Evgenii, Feuerstein, Burt G, Preul, Mark, Scheck, Adrienne C, Reiser, Mark, Anderson, Trent, Gopez, Jonas, Appelt, Denah, Yocom, Steven, Eschbacher, Jennifer, Yan, Hao, Nakaji, Peter

“…Differentiating central nervous system (CNS) lymphoma from other intracranial malignancies remains a clinical challenge in surgical neuro-oncology. Advances in…”
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