Search Results - "Schauwecker, J."

Blockade of BCL-2 proteins efficiently induces apoptosis in progenitor cells of high-risk myelodysplastic syndromes patients by Jilg, S, Reidel, V, Müller-Thomas, C, König, J, Schauwecker, J, Höckendorf, U, Huberle, C, Gorka, O, Schmidt, B, Burgkart, R, Ruland, J, Kolb, H-J, Peschel, C, Oostendorp, R A J, Götze, K S, Jost, P J

“…Deregulated apoptosis is an identifying feature of myelodysplastic syndromes (MDS). Whereas apoptosis is increased in the bone marrow (BM) of low-risk MDS…”
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High-throughput library transgenesis in Caenorhabditis elegans via Transgenic Arrays Resulting in Diversity of Integrated Sequences (TARDIS) by Stevenson, Zachary C, Moerdyk-Schauwecker, Megan J, Banse, Stephen A, Patel, Dhaval S, Lu, Hang, Phillips, Patrick C

“…High-throughput transgenesis using synthetic DNA libraries is a powerful method for systematically exploring genetic function. Diverse synthesized libraries…”
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Post-insemination selection dominates pre-insemination selection in driving rapid evolution of male competitive ability by Kasimatis, Katja R, Moerdyk-Schauwecker, Megan J, Lancaster, Ruben, Smith, Alexander, Willis, John H, Phillips, Patrick C

“…Sexual reproduction is a complex process that contributes to differences between the sexes and divergence between species. From a male's perspective, sexual…”
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Rapid Self-Selecting and Clone-Free Integration of Transgenes into Engineered CRISPR Safe Harbor Locations in Caenorhabditis elegans by Stevenson, Zachary C, Moerdyk-Schauwecker, Megan J, Jamison, Brennen, Phillips, Patrick C

“…Precision genome editing for model organisms has revolutionized functional analysis and validation of a wide variety of molecular systems. To date, the…”
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Proteomic and evolutionary analyses of sperm activation identify uncharacterized genes in Caenorhabditis nematodes by Kasimatis, Katja R, Moerdyk-Schauwecker, Megan J, Timmermeyer, Nadine, Phillips, Patrick C

“…Nematode sperm have unique and highly diverged morphology and molecular biology. In particular, nematode sperm contain subcellular vesicles known as membranous…”
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Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus by Hastie, Eric, Cataldi, Marcela, Moerdyk-Schauwecker, Megan J, Felt, Sébastien A, Steuerwald, Nury, Grdzelishvili, Valery Z

“…Vesicular stomatitis virus (VSV) based recombinant viruses (such as VSV-ΔM51) are effective oncolytic viruses (OVs) against a majority of pancreatic ductal…”
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Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P by Burmeister, Amanda R, Johnson, M Brittany, Chauhan, Vinita S, Moerdyk-Schauwecker, Megan J, Young, Ada D, Cooley, Ian D, Martinez, Alejandra N, Ramesh, Geeta, Philipp, Mario T, Marriott, Ian

“…The tachykinin substance P (SP) is recognized to exacerbate inflammation at peripheral sites via its target receptor, neurokinin 1 receptor (NK-1R), expressed…”
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A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells by Furr, Samantha R, Chauhan, Vinita S, Moerdyk-Schauwecker, Megan J, Marriott, Ian

“…The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Microglia and astrocytes are likely to play a significant…”
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Surgical therapy of ischiofemoral impingement by lateralizing intertrochanteric osteotomy by Suren, C, Burgkart, R, Banke, I J, Hertel, G, Schauwecker, J, von Eisenhart-Rothe, R, Gollwitzer, H

“…Lateralizing, derotating intertrochanteric varus osteotomy to increase the ischiofemoral space to counter painful impingement of the lesser trochanter and the…”
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BCL-2 Inhibition by ABT-199 Potently Induces Cell Death in MDS Progenitors Despite High-Risk Mutations in ASXL1, RUNX1, TP53 or EZH2 by Jilg, S, Reidel, V, Kauschinger, J, Müller-Thomas, C, Hauch, R, Schauwecker, J, Burkhard, S, Höckendorf, U, Peschel, C, Kern, W, Haferlach, T, Slotta-Huspenina, J, Götze, K.S, Jost, P.J

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27 BLOCKADE OF BCL-2 PROTEINS EFFICIENTLY INDUCES APOPTOSIS IN PROGENITOR CELLS OF HIGH-RISK MYELODYSPLASTIC SYNDROMES (MDS) PATIENTS by Jilg, S, Reidel, V, Mueller-Thomas, C, Koenig, J, Schauwecker, J, Burgkart, R, Hoeckendorf, U, Huberle, C, Gorka, O, Ruland, J, Kolb, H, Peschel, C, Oostendorp, R, Goetze, K, Jost, P

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P-016 Resistance to apoptosis in high-risk myelodysplastic syndrome can be overcome by pro-apoptotic drug treatment using ABT-737 by Jilg, S, König, J, Höckendorf, U, Schauwecker, J, Huberle, C, Müller-Thomas, C, Schmidt, B, Burgkart, R, Götze, K, Kolb, H.J, Peschel, C, Jost, P.J

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Auxin-Mediated Sterility Induction System for Longevity and Mating Studies in Caenorhabditis elegans by Kasimatis, Katja R, Moerdyk-Schauwecker, Megan J, Phillips, Patrick C

“…The ability to control both the means and timing of sexual reproduction provides a powerful tool to understand not only fertilization but also life history…”
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Effects of cefuroxime on human osteoblasts in vitro by Salzmann, G.M., Naal, F.D., von Knoch, F., Tuebel, J., Gradinger, R., Imhoff, A.B., Schauwecker, J.

“…The local application of antibiotics in bone cement achieves high local effective antibiotic concentrations. Cefuroxime is widely used for antibiotic…”
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Recalling Open Old Growth Forests in the Southeastern Mixed Forest Province of the United States by Hanberry, Brice B., Brzuszek, Robert F., Foster, H. Thomas, Schauwecker, Timothy J.

“…Historical forests in the Southeastern Mixed Forest province of the United States have been less researched than other regions using historical tree surveys…”
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Induction of apoptosis in pancreatic cancer cells by vesicular stomatitis virus by Felt, Sébastien A, Moerdyk-Schauwecker, Megan J, Grdzelishvili, Valery Z

“…Abstract Effective oncolytic virus (OV) therapy is dependent on the ability of replication-competent viruses to kill infected cancer cells. We previously…”
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Nicht nur vor, auch nach der Op. können Sie das Risiko minimieren by Banke, Ingo J., Suren, Christian, Schauwecker, J., von Eisenhart-Rothe, Rüdiger, Mühlhofer, Heinrich M. L.

“…Um implantatassoziierte Infekte zu vermeiden, ist die konsequente prä- und postoperative Prophylaxe von allergrößter Bedeutung. Welche Möglichkeiten Ihnen als…”
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High hydrostatic pressure as an alternatve sterilization method to irradiation or autoclaving of tumor-afflicted bone? by Diehl, P., Steinhauser, E., Schauwecker, J., Schmitt, M., Magdolen, U., Gradinger, R., Mittelmeier, W.

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Hip arthroscopy by Gollwitzer, H, Banke, I J, Schauwecker, J

“…Hip arthroscopy represents an important component in the treatment of diseases of the hip joint and is nowadays an indispensible tool in modern hip-preserving…”
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Septic endoprosthesis exchange : Preoperative diagnosis and reimplantation by Mühlhofer, H M L, Schauwecker, J, Banke, I J, von Eisenhart-Rothe, R

“…The treatment of prosthetic joint infection (PJI) is truly challenging. Patients with infected arthroplasty face physical and psychosocial problems…”
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