Search Results - "Schank, J. R."

Dependence-induced increase of alcohol self-administration and compulsive drinking mediated by the histone methyltransferase PRDM2 by Barbier, E, Johnstone, A L, Khomtchouk, B B, Tapocik, J D, Pitcairn, C, Rehman, F, Augier, E, Borich, A, Schank, J R, Rienas, C A, Van Booven, D J, Sun, H, Nätt, D, Wahlestedt, C, Heilig, M

“…Epigenetic processes have been implicated in the pathophysiology of alcohol dependence, but the specific molecular mechanisms mediating dependence-induced…”
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The Role of NFkB in Drug Addiction: Beyond Inflammation by Nennig, S E, Schank, J R

“…Nuclear factor kappa light chain enhancer of activated B cells (NFkB) is a ubiquitous transcription factor well known for its role in the innate immune…”
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The effects of lipopolysaccharide exposure on social interaction, cytokine expression, and alcohol consumption in male and female mice by Decker Ramirez, E.B., Arnold, M.E., McConnell, K.T., Solomon, M.G., Amico, K.N., Schank, J.R.

“…•LPS injection induces social avoidance in female mice.•LPS induces cytokine expression in both males and females.•LPS increases alcohol intake in both males…”
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Live predator stress in adolescence results in distinct adult behavioral consequences and dorsal diencephalic brain activation patterns by Tapocik, J.D., Schank, J.R., Mitchell, J.R., Damazdic, R., Mayo, C.L., Brady, D., Pincus, A.B., King, C.E., Heilig, M., Elmer, G.I.

“…Exposure to traumatic events during childhood increases the risk of adult psychopathology, including anxiety, depression, alcohol use disorders and their…”
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Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence by Tapocik, J D, Solomon, M, Flanigan, M, Meinhardt, M, Barbier, E, Schank, J R, Schwandt, M, Sommer, W H, Heilig, M

“…Long-term changes in brain gene expression have been identified in alcohol dependence, but underlying mechanisms remain unknown. Here, we examined the…”
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Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training by Augier, E., Flanigan, M., Dulman, R. S., Pincus, A., Schank, J. R., Rice, K.C., Kejun, C., Heilig, M., Tapocik, J. D.

“…Rationale Operant self-administration (SA) is an important model of motivation to consume ethanol (EtOH), but low rates of voluntary consumption in rats are…”
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Selective Lesioning of Nuclear Factor-κB Activated Cells in the Nucleus Accumbens Shell Attenuates Alcohol Place Preference by Nennig, S E, Fulenwider, H D, Chimberoff, S H, Smith, B M, Eskew, J E, Sequeira, M K, Karlsson, C, Liang, C, Chen, J F, Heilig, M, Schank, J R

“…Nuclear factor κ-light chain enhancer of activated B cells (NF-κB) is a transcription factor commonly associated with innate immunity and is activated by…”
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Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking by Schank, J.R., Nelson, B.S., Damadzic, R., Tapocik, J.D., Yao, M., King, C.E., Rowe, K.E., Cheng, K., Rice, K.C., Heilig, M.

“…Substance P (SP) and its cognate neurokinin-1 receptor (NK1R) are involved in alcohol-related behaviors. We have previously reported that NK1R antagonism…”
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The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation by Karlsson, Camilla, Rehman, Faazal, Damdazic, Ruslan, Atkins, Alison L., Schank, Jesse R., Gehlert, Donald R., Steensland, Pia, Thorsell, Annika, Heilig, Markus

“…Rationale Melanin-concentrating hormone (MCH) is involved in the regulation of food intake and has recently been associated with alcohol-related behaviors…”
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Selective Lesioning of Nuclear Factor-[kappa]B Activated Cells in the Nucleus Accumbens Shell Attenuates Alcohol Place Preference by Nennig, S E, Fulenwider, H D, Chimberoff, S H, Smith, B M, Eskew, J E, Sequeira, M K, Karlsson, C, Liang, C, Chen, J F, Heilig, M, Schank, J R

“…Nuclear factor κ-light chain enhancer of activated B cells (NF-κB) is a transcription factor commonly associated with innate immunity and is activated by…”
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Epigenetic enzymes as a novel class of targets for disease-modifying pharmacotherapies in alcohol addiction by Barbier, E, Johnstone, A.L, Khomtchouk, B.B, Tapocik, J.D, Pitcairn, C, Rehman, F, Augier, E, Borich, A, Schank, J.R, Rienas, C.A, Van Booven, D.J, Sun, H, Nätt, D, Wahlestedt, C, Heilig, M

“…Conversely, PRDM2 knockdown in non-dependent rats induced a set of gene expression changes that overlapped with those found following alcohol dependence…”
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The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation (vol 233, pg 2355, 2016) by Karlsson, C, Rehman, F, Damadzic, R, Atkins, AL, Schank, JR, Gehlert, DR, Steensland, P, Thorsell, A, Heilig, M

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Erratum to: The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation by Karlsson, Camilla, Rehman, Faazal, Damadzic, Ruslan, Atkins, Alison L., Schank, Jesse R., Gehlert, Donald R., Steensland, Pia, Thorsell, Annika, Heilig, Markus

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Stress-Related Neuropeptides and Addictive Behaviors: Beyond the Usual Suspects by Schank, Jesse R., Ryabinin, Andrey E., Giardino, William J., Ciccocioppo, Roberto, Heilig, Markus

“…Addictive disorders are chronic, relapsing conditions that cause extensive disease burden. Genetic factors partly account for susceptibility to addiction, but…”
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THEMELANIN-CONCENTRATTING HORMONE-1 RECEPTOR (MCH-1R) MODULATES ALCOHOL-INDUCED REWARD AND P-DARPP-32 STIMULATION by Karlsson, C, Rehman, F, Damadzic, R, Schank, JR, Gehlert, DR, Stensland, P, Thorsell, A, Heilig, M

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THE IL-1 RECEPTOR INFLUENCES ALCOHOL CONSUMPTION IN C57 MICE by Karlsson, C, Rehman, F, Barbier, E, Salomon, M, Tapocik, J, Thorsell, A, Heilig, M, Schank, JR

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