Search Results - "Schaner, Philip"

Dosimetric Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Squamous Cell Carcinoma of the Head and Neck by Caudell, Jimmy J., M.D., Ph.D, Schaner, Philip E., M.D., Ph.D, Desmond, Renee A., D.V.M, Ph.D, Meredith, Ruby F., M.D., Ph.D, Spencer, Sharon A., M.D, Bonner, James A., M.D

“…Purpose Intensification of radiotherapy and chemotherapy for head-and-neck cancer may lead to increased rates of dysphagia. Dosimetric predictors of objective…”
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Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Locally Advanced Head-and-Neck Cancer by Caudell, Jimmy J., M.D., Ph.D, Schaner, Philip E., M.D., Ph.D, Meredith, Ruby F., M.D., Ph.D, Locher, Julie L., Ph.D, Nabell, Lisle M., M.D, Carroll, William R., M.D, Magnuson, J. Scott, M.D, Spencer, Sharon A., M.D, Bonner, James A., M.D

“…Purpose The use of altered fractionation radiotherapy (RT) regimens, as well as concomitant chemotherapy and RT, to intensify therapy for locally advanced…”
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Surface dielectric resonator for in vivo EPR measurements by Petryakov, Sergey V., Kmiec, Maciej M., Ubert, Conner S., Kassey, Victor B., Schaner, Philip E., Kuppusamy, Periannan

“…[Display omitted] •A novel surface dielectric resonator with flexible connector.•Suitable for in vivo electron paramagnetic resonance spectroscopy.•Constructed…”
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Initial Clinical Experience of Cherenkov Imaging in External Beam Radiation Therapy Identifies Opportunities to Improve Treatment Delivery by Jarvis, Lesley A., Hachadorian, Rachael L., Jermyn, Michael, Bruza, Petr, Alexander, Daniel A., Tendler, Irwin I., Williams, Benjamin B., Gladstone, David J., Schaner, Philip E., Zaki, Bassem I., Pogue, Brian W.

“…The value of Cherenkov imaging as an on-patient, real-time, treatment delivery verification system was examined in a 64-patient cohort during routine radiation…”
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OxyChip embedded with radio‐opaque gold nanoparticles for anatomic registration and oximetry in tissues by Kmiec, Maciej M., Hebert, Kendra A., Tse, Dan, Hodge, Sassan, Williams, Benjamin B., Schaner, Philip E., Kuppusamy, Periannan

“…Purpose Electron paramagnetic resonance oximetry using the OxyChip as an implantable oxygen sensor can directly and repeatedly measure tissue oxygen levels. A…”
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Transcutaneous oxygen measurement in humans using a paramagnetic skin adhesive film by Kmiec, Maciej M., Hou, Huagang, Lakshmi Kuppusamy, M., Drews, Thomas M., Prabhat, Anjali M., Petryakov, Sergey V., Demidenko, Eugene, Schaner, Philip E., Buckey, Jay C., Blank, Aharon, Kuppusamy, Periannan

“…Purpose Transcutaneous oxygen tension (TcpO2) provides information about blood perfusion in the tissue immediately below the skin. These data are valuable in…”
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Decreasing the Dose and Volume of Elective Nodal Radiotherapy in HPV-Associated Oropharyngeal Cancer: How Low Can We Go? by Schaner, Philip E, Chandra, Ravi A

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Treatment Planning System for Electron FLASH Radiation Therapy: Open-Source for Clinical Implementation by Rahman, Mahbubur, Ashraf, M. Ramish, Gladstone, David J., Bruza, Petr, Jarvis, Lesley A., Schaner, Philip E., Cao, Xu, Pogue, Brian W., Hoopes, P. Jack, Zhang, Rongxiao

“…To present a Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) for a modified ultrahigh…”
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Addition of Metformin to Concurrent Chemoradiation in Patients With Locally Advanced Non-Small Cell Lung Cancer: The NRG-LU001 Phase 2 Randomized Clinical Trial by Skinner, Heath, Hu, Chen, Tsakiridis, Theodoros, Santana-Davila, Rafael, Lu, Bo, Erasmus, Jeremy J, Doemer, Anthony J, Videtic, Gregory M M, Coster, James, Yang, Alex Xuezhong, Lee, Richard Y, Werner-Wasik, Maria, Schaner, Philip E, McCormack, Steven E, Esparaz, Benjamin T, McGarry, Ronald C, Bazan, Jose, Struve, Timothy, Paulus, Rebecca, Bradley, Jeffrey D

“…Non-small cell lung cancer (NSCLC) has relatively poor outcomes. Metformin has significant data supporting its use as an antineoplastic agent. To compare…”
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Assessment of imaging Cherenkov and scintillation signals in head and neck radiotherapy by Alexander, Daniel A, Tendler, Irwin I, Bruza, Petr, Cao, Xu, Schaner, Philip E, Marshall, Bethany S, Jarvis, Lesley A, Gladstone, David J, Pogue, Brian W

“…The goal of this study was to test the utility of time-gated optical imaging of head and neck (HN) radiotherapy treatments to measure surface dosimetry in…”
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Comparison of Tumor Control and Skin Damage in a Mouse Model after Ultra-High Dose Rate Irradiation and Conventional Irradiation by Duval, Kayla E. A., Aulwes, Ethan, Zhang, Rongxiao, Rahman, Mahbubur, Ashraf, M. Ramish, Sloop, Austin, Sunnerberg, Jacob, Williams, Benjamin B., Cao, Xu, Bruza, Petr, Kheirollah, Alireza, Tavakkoli, Armin, Jarvis, Lesley A., Schaner, Philip E., Swartz, Harold M., Gladstone, David J., Pogue, Brian W., Hoopes, P. Jack

“…Recent studies suggest ultra-high dose rate radiation treatment (UHDR-RT) reduces normal tissue damage compared to conventional radiation treatment (CONV-RT)…”
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How best to interpret measures of levels of oxygen in tissues to make them effective clinical tools for care of patients with cancer and other oxygen‐dependent pathologies by Swartz, Harold M., Flood, Ann Barry, Schaner, Philip E., Halpern, Howard, Williams, Benjamin B., Pogue, Brian W., Gallez, Bernard, Vaupel, Peter

“…It is well understood that the level of molecular oxygen (O2) in tissue is a very important factor impacting both physiology and pathological processes as well…”
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The impact of particulate electron paramagnetic resonance oxygen sensors on fluorodeoxyglucose imaging characteristics detected via positron emission tomography by Schaner, Philip E., Tran, Ly-Binh-An, Zaki, Bassem I., Swartz, Harold M., Demidenko, Eugene, Williams, Benjamin B., Siegel, Alan, Kuppusamy, Periannan, Flood, Ann Barry, Gallez, Bernard

“…During a first-in-humans clinical trial investigating electron paramagnetic resonance tumor oximetry, a patient injected with the particulate oxygen sensor…”
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What Is the Meaning of an Oxygen Measurement? : Analysis of Methods Purporting to Measure Oxygen in Targeted Tissues by Swartz, Harold M, Flood, Ann Barry, Williams, Benjamin B, Pogue, Brian W, Schaner, Philip E, Vaupel, Peter

“…Clinical measurements of O in tissues will inevitably provide data that are at best aggregated and will not reflect the inherent heterogeneity of O in tissues…”
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In Vivo CW-EPR Spectrometer Systems for Dosimetry and Oximetry in Preclinical and Clinical Applications by Schreiber, Wilson, Petryakov, Sergey V., Kmiec, Maciej M., Flood, Ann Barry, Swartz, Harold M., Schaner, Philip E., Williams, Benjamin B.

“…EPR spectrometers (and various sub-systems) have been designed and constructed to facilitate in vivo measurements with human subjects for dosimetry and…”
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Flexible Segmented Surface Coil Resonator for In Vivo EPR Measurements in Human Subjects by Petryakov, Sergey, Schreiber, Wilson, Kmiec, Maciej, Swartz, Harold M., Schaner, Philip E., Kuppusamy, Periannan, Williams, Benjamin B.

“…There is a strong need to enable accurate and convenient oxygen measurements in vivo for human subjects to improve treatments for cancer, peripheral vascular…”
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OxyChip Implantation and Subsequent Electron Paramagnetic Resonance Oximetry in Human Tumors Is Safe and Feasible: First Experience in 24 Patients by Schaner, Philip E., Pettus, Jason R., Flood, Ann Barry, Williams, Benjamin B., Jarvis, Lesley A., Chen, Eunice Y., Pastel, David A., Zuurbier, Rebecca A., diFlorio-Alexander, Roberta M., Swartz, Harold M., Kuppusamy, Periannan

“…Introduction: Tumor hypoxia confers both a poor prognosis and increased resistance to oncologic therapies, and therefore, hypoxia modification with reliable…”
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First-In-Human Study in Cancer Patients Establishing the Feasibility of Oxygen Measurements in Tumors Using Electron Paramagnetic Resonance With the OxyChip by Schaner, Philip E, Williams, Benjamin B, Chen, Eunice Y, Pettus, Jason R, Schreiber, Wilson A, Kmiec, Maciej M, Jarvis, Lesley A, Pastel, David A, Zuurbier, Rebecca A, DiFlorio-Alexander, Roberta M, Paydarfar, Joseph A, Gosselin, Benoit J, Barth, Richard J, Rosenkranz, Kari M, Petryakov, Sergey V, Hou, Huagang, Tse, Dan, Pletnev, Alexandre, Flood, Ann Barry, Wood, Victoria A, Hebert, Kendra A, Mosher, Robyn E, Demidenko, Eugene, Swartz, Harold M, Kuppusamy, Periannan

“…The overall objective of this clinical study was to validate an implantable oxygen sensor, called the 'OxyChip', as a clinically feasible technology that would…”
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Application of SPOT chip for transcutaneous oximetry by Kmiec, Maciej M., Hou, Huagang, Kuppusamy, M. Lakshmi, Drews, Thomas M., Prabhat, Anjali M., Petryakov, Sergey V., Demidenko, Eugene, Schaner, Philip E., Buckey, Jay C., Blank, Aharon, Kuppusamy, Periannan

“…This response is provided to address the questions raised in the letter to the editor by Henni et al. on our manuscript (Kmiec et al. Magn Reson Med…”
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Evaluation of a Refined Implantable Resonator for Deep-Tissue EPR Oximetry in the Clinic by Chen, Eunice Y., Tse, Dan, Hou, Huagang, Schreiber, Wilson A., Schaner, Philip E., Kmiec, Maciej M., Hebert, Kendra A., Kuppusamy, Periannan, Swartz, Harold M., Williams, Benjamin B.

“…(1) Summarize revisions made to the implantable resonator (IR) design and results of testing to characterize biocompatibility; (2) Demonstrate safety of…”
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