Search Results - "Schalkwyk, Leonard S"
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Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array
Published in BMC genomics (14-05-2019)“…There has been a steady increase in the number of studies aiming to identify DNA methylation differences associated with complex phenotypes. Many of the…”
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Uncertainty quantification of reference-based cellular deconvolution algorithms
Published in Epigenetics (31-12-2023)“…The majority of epigenetic epidemiology studies to date have generated genome-wide profiles from bulk tissues (e.g., whole blood) however these are vulnerable…”
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Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains
Published in Molecular brain (28-01-2019)“…Most variants associated with complex phenotypes in genome-wide association studies (GWAS) do not directly index coding changes affecting protein structure…”
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DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia
Published in eLife (26-02-2021)“…We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially…”
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The correlation between reading and mathematics ability at age twelve has a substantial genetic component
Published in Nature communications (08-07-2014)“…Dissecting how genetic and environmental influences impact on learning is helpful for maximizing numeracy and literacy. Here we show, using twin and…”
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