Search Results - "Schalkwyk, L."
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Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits
Published in Molecular psychiatry (01-04-2014)“…Autism spectrum disorder (ASD) defines a group of common, complex neurodevelopmental disorders. Although the aetiology of ASD has a strong genetic component,…”
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Advanced paternal age effects in neurodevelopmental disorders—review of potential underlying mechanisms
Published in Translational psychiatry (31-01-2017)“…Multiple epidemiological studies suggest a relationship between advanced paternal age (APA) at conception and adverse neurodevelopmental outcomes in offspring,…”
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Endemic persistence of a highly contagious pathogen: Foot-and-mouth disease in its wildlife host
Published in Science (American Association for the Advancement of Science) (01-10-2021)“…Extremely contagious pathogens are a global biosecurity threat because of their high burden of morbidity and mortality, as well as their capacity for…”
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Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder
Published in Molecular psychiatry (01-05-2018)“…In order to determine the impact of the epigenetic response to traumatic stress on post-traumatic stress disorder (PTSD), this study examined longitudinal…”
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Quantitative trait locus association scan of early reading disability and ability using pooled DNA and 100K SNP microarrays in a sample of 5760 children
Published in Molecular psychiatry (01-07-2008)“…Quantitative genetic research suggests that reading disability is the quantitative extreme of the same genetic and environmental factors responsible for normal…”
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Spatial partitioning by a subordinate carnivore is mediated by conspecific overlap
Published in Oecologia (01-11-2019)“…There are several hypotheses that could explain territory size in mammals, including the resource dispersion hypothesis (RDH), the intruder pressure hypothesis…”
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DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP
Published in Translational psychiatry (03-09-2013)“…Transcriptional differences in interleukin-11 ( IL11 ) after antidepressant treatment have been found to correspond to clinical response in major depressive…”
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Maternal separation is associated with strain‐specific responses to stress and epigenetic alterations to Nr3c1, Avp, and Nr4a1 in mouse
Published in Brain and behavior (01-07-2012)“…Stressful events early in life have been widely linked to behavioral phenotypes and have been implicated in the development of psychiatric disorders. Using a…”
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Genetics of behavioural domains across the neuropsychiatric spectrum; of mice and men
Published in Molecular psychiatry (01-04-2007)“…Family and twin studies have revealed that genetic factors play a major role in psychiatric disorders, however, attempts to find susceptibility genes for these…”
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The differential transcriptome and ontology profiles of floating and cumulus granulosa cells in stimulated human antral follicles
Published in Molecular human reproduction (01-04-2010)“…Communication between various ovarian cell types is a prerequisite for folliculogenesis and ovulation. In antral follicles granulosa cells divide into two…”
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Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes
Published in Translational psychiatry (03-03-2015)“…Despite moderate heritability estimates, progress in uncovering the molecular substrate underpinning major depressive disorder (MDD) has been slow. In this…”
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ViPAR: a software platform for the Virtual Pooling and Analysis of Research Data
Published in International journal of epidemiology (01-04-2016)“…Research studies exploring the determinants of disease require sufficient statistical power to detect meaningful effects. Sample size is often increased…”
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Effects of advanced paternal age on trajectories of social behavior in offspring
Published in Genes, brain and behavior (01-07-2015)“…Our study is the first investigation of the effects of advanced paternal age (APA) on the developmental trajectory of social behavior in rodent offspring…”
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Antibody response to Raboral VR-G® oral rabies vaccine in captive and free-ranging black-backed jackals ()
Published in Onderstepoort journal of veterinary research (10-02-2022)“…Rabies is a zoonotic disease that remains endemic in large parts of southern Africa because of its persistence in wildlife and domestic dog vectors. The…”
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A genome‐wide association study identifies multiple loci associated with mathematics ability and disability
Published in Genes, brain and behavior (01-03-2010)“…Numeracy is as important as literacy and exhibits a similar frequency of disability. Although its etiology is relatively poorly understood, quantitative…”
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Carcass Yields and Physical-Chemical Meat Quality Characteristics of Namibian Red Hartebeest ( A lcelaphus buselaphus ) as Influenced by Sex and Muscle
Published in Foods (01-10-2021)“…This study determined the carcass yields of red hartebeest from Namibia and compared the physical-chemical meat quality characteristics of six different…”
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Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway
Published in Physiological genomics (13-05-2009)“…1 Department of Physiology, University of Tartu 2 Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences 3 Department of…”
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Description of Events Where African Buffaloes (Syncerus caffer) Strayed from the Endemic Foot‐and‐Mouth Disease Zone in South Africa, 1998–2008
Published in Transboundary and emerging diseases (01-06-2016)“…African buffaloes (Syncerus caffer) are reservoir hosts of Southern African Territories (SAT) foot‐and‐mouth disease (FMD) virus strains. In South Africa,…”
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Performance deficit of alpha 7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working-episodic-like memory
Published in Genes, brain and behavior (01-08-2006)“…Patients with schizophrenia exhibit deficits in a range of cognitive functions, particularly working and episodic memory, which are thought to be core features…”
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