Search Results - "Schalekamp, M A"

Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus by DEINUM, J, RØNN, B, MATHIESEN, E, DERKX, F. H. M, HOP, W. C. J, SCHALEKAMP, M. A. D. H

“…The renin-angiotensin system is possibly involved in the pathogenesis of diabetic nephropathy. The most striking change in renin-angiotensin system components…”
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Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin-angiotensin system by Wagner, J, Jan Danser, A H, Derkx, F H, de Jong, T V, Paul, M, Mullins, J J, Schalekamp, M A, Ganten, D

“…AIMS/BACKGROUND: All components necessary for the formation of angiotensin II, the biologically active product of the renin-angiotensin system (RAS), have been…”
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Cardiac Renin and Angiotensins: Uptake From Plasma Versus In Situ Synthesis by Danser, A H. Jan, van Kats, Jorge P, Admiraal, Peter J.J, Derkx, Frans H.M, Lamers, Jos M.J, Verdouw, Pieter D, Saxena, Pramod R, Schalekamp, Maarten A.D.H

“…The existence of a cardiac renin-angiotensin system, independent of the circulating renin-angiotensin system, is still controversial. We compared the tissue…”
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Angiotensin II production and distribution in the kidney: I. A kinetic model by Schalekamp, M.A.D.H., Danser, A.H.J.

“…Information on the levels of angiotensin II (Ang II) and its receptors in the various renal tissue compartments is still incomplete. A model is presented…”
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Angiotensin II production and distribution in the kidney – II. Model-based analysis of experimental data by Schalekamp, M.A.D.H., Danser, A.H.J.

“…Information on the regional concentrations of angiotensin (Ang) II and its type-1 and -2 receptors (AT1R, AT2R) in the kidney is still incomplete. Published…”
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Optimal collection and storage conditions for catecholamine measurements in human plasma and urine by Boomsma, F, Alberts, G, van Eijk, L, Man in 't Veld, A J, Schalekamp, M A

“…Improvements in methodologies for measuring concentrations of catecholamines (CA) have led to an increasing use of these compounds as markers in the screening…”
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Clinical validation of renin monoclonal antibody-based sandwich assays of renin and prorenin, and use of renin inhibitor to enhance prorenin immunoreactivity by Derkx, FH, de Bruin, RJ, van Gool, JM, van den Hoek, MJ, Beerendonk, CC, Rosmalen, F, Haima, P, Schalekamp, MA

“…Newly developed IRMAs to measure the plasma concentrations of renin and prorenin were validated for clinical use and compared with a classical enzyme kinetic…”
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Angiotensin levels in the eye by Danser, AH, Derkx, FH, Admiraal, PJ, Deinum, J, de Jong, PT, Schalekamp, MA

“…Ocular tissues contain renin and ocular fluids contain prorenin in amounts that are too high to be explained by admixture with blood or diffusion from blood…”
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Human renal and systemic hemodynamic, natriuretic, and neurohumoral responses to different doses of L-NAME by Broere, A, Van Den Meiracker, A H, Boomsma, F, Derkx, F H, Veld, A J, Schalekamp, M A

“…Experimental evidence indicates that the renal circulation is more sensitive to the effects of nitric oxide (NO) synthesis inhibition than other vascular beds…”
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Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy by Danser, A H, van den Dorpel, M A, Deinum, J, Derkx, F H, Franken, A A, Peperkamp, E, de Jong, P T, Schalekamp, M A

“…Renin, prorenin, and immunoreactive renin were present in vitreous and subretinal fluid of eyes from subjects with and without diabetic retinopathy. Renin…”
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Production of angiotensins I and II at tissue sites in intact pigs by Danser, A H, Koning, M M, Admiraal, P J, Sassen, L M, Derkx, F H, Verdouw, P D, Schalekamp, M A

“…To estimate the contribution of angiotensin (ANG) I and II production at tissue sites to the circulating levels, ANG I and II and their radiolabeled…”
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Angiotensin-converting enzyme in the human heart : effect of the deletion/insertion polymorphism by DANSER, A. H. J, SCHALEKAMP, M. A. D. H, BAX, W. A, MAASSEN VAN DEN BRINK, A, SAXENA, P. R, RIEGGER, G. A. J, SCHUNKERT, H

“…An insertion (I)/deletion (D) polymorphism of the angiotensin-converting enzyme (ACE) gene has been associated with differences in the plasma levels of ACE as…”
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Metabolism and Production of Angiotensin I in Different Vascular Beds in Subjects With Hypertension by Admiraal, Peter J.J, Derkx, Frans H.M, Danser, A H. Jan, Pieterman, Herman, Schalekamp, Maarten A.D.H

“…To study the metabolism and production of angiotensin I, highly purified monoiodinated [I25I] angiotensin I was given by constant systemic intravenous…”
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A clinical prediction rule for renal artery stenosis by KRIJNEN, P, VAN JAARSVELD, B. C, STEYERBERG, E. W, MAN IN'T VELD, A. J, SCHALEKAMP, M. A. D. H, HABBEMA, J. D. F

“…Renal artery stenosis is a rare cause of hypertension. The gold standard for diagnosing renal artery stenosis, renal angiography, is invasive and costly. To…”
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Immunoreactive renin, prorenin, and enzymatically active renin in plasma during pregnancy and in women taking oral contraceptives by Derkx, F H, Steunkel, C, Schalekamp, M P, Visser, W, Huisveld, I H, Schalekamp, M A

“…Direct RIA of renin with monoclonal renin antibodies and indirect RIA with angiotensin I antibodies were performed in plasma of 44 pregnant women, 44 women…”
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Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans by Jan Danser, A H, Derkx, Frans H.M, Schalekamp, Maarten A.D.H, Hense, Hans-Werner, Riegger, Günter A.J, Schunkert, Heribert

“…BACKGROUNDPlasma renin concentrations are an important factor in cardiovascular risk profiling. OBJECTIVETo investigate the effects of sex, medication, and…”
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Renal Hemodynamics and the Renin–Angiotensin–Aldosterone System in Normotensive Subjects with Hypertensive and Normotensive Parents by van Hooft, Ingrid M.S, Grobbee, Diederick E, Derkx, Frans H.M, de Leeuw, Peter W, Schalekamp, Maarten A.D.H, Hofman, Albert

“…THE role of the kidney as a long-term regulator of blood volume and blood pressure is well established. 1 Any increase in blood pressure is compensated for by…”
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High plasma prorenin in diabetes mellitus and its correlation with some complications by Franken, A A, Derkx, F H, Man in't Veld, A J, Hop, W C, van Rens, G H, Peperkamp, E, de Jong, P T, Schalekamp, M A

“…Plasma prorenin is abnormally high, whereas renin is normal or even low, in many patients with long-standing diabetes mellitus complicated by microvascular…”
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Metabolism of angiotensin I by different tissues in the intact animal by Danser, A H, Koning, M M, Admiraal, P J, Derkx, F H, Verdouw, P D, Schalekamp, M A

“…To quantify regional conversion of angiotensin (ANG) I to ANG II and its degradation to peptides other than ANG II, monoiodinated 125I-labeled ANG I was given…”
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Effect of atrial natriuretic peptide on renal and vascular permeability in diabetes mellitus by Zietse, R, Derkx, F H, Weimar, W, Schalekamp, M A

“…Synthetic human atrial natriuretic peptide (ANP) (102-126) 0.01 microgram/kg per minute or vehicle was intravenously infused for 2 h in 10 patients with…”
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