Search Results - "Schakman, O"

Glucocorticoid-induced skeletal muscle atrophy by Schakman, O., Kalista, S., Barbé, C., Loumaye, A., Thissen, J.P.

“…Many pathological states characterized by muscle atrophy (e.g., sepsis, cachexia, starvation, metabolic acidosis and severe insulinopenia) are associated with…”
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Mechanisms of glucocorticoid-induced myopathy by Schakman, O, Gilson, H, Thissen, J P

“…Glucocorticoid-induced muscle atrophy is characterized by fast-twitch or type II muscle fiber atrophy illustrated by decreased fiber cross-sectional area and…”
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Neural progenitor fate decision defects, cortical hypoplasia and behavioral impairment in Celsr1-deficient mice by Boucherie, C, Boutin, C, Jossin, Y, Schakman, O, Goffinet, A M, Ris, L, Gailly, P, Tissir, F

“…The development of the cerebral cortex is a tightly regulated process that relies on exquisitely coordinated actions of intrinsic and extrinsic cues. Here, we…”
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Mechanisms of muscle atrophy induced by glucocorticoids by Schakman, O, Gilson, H, Kalista, S, Thissen, J P

“…Many pathological states characterized by muscle atrophy (e.g., sepsis, cachexia, starvation, metabolic acidosis and severe insulinopenia) are associated with…”
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The Type 1 Insulin-Like Growth Factor Receptor (IGF-IR) Pathway Is Mandatory for the Follistatin-Induced Skeletal Muscle Hypertrophy by Kalista, S, Schakman, O, Gilson, H, Lause, P, Demeulder, B, Bertrand, L, Pende, M, Thissen, J. P

“…Myostatin inhibition by follistatin (FS) offers a new approach for muscle mass enhancement. The aim of the present study was to characterize the mediators…”
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Myostatin Gene Deletion Prevents Glucocorticoid-Induced Muscle Atrophy by Gilson, H, Schakman, O, Combaret, L, Lause, P, Grobet, L, Attaix, D, Ketelslegers, J. M, Thissen, J. P

“…Glucocorticoids mediate muscle atrophy in many catabolic states. Myostatin expression, a negative regulator of muscle growth, is increased by glucocorticoids…”
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Role of IGF-I and the TNFα/NF-κB pathway in the induction of muscle atrogenes by acute inflammation by Schakman, O, Dehoux, M, Bouchuari, S, Delaere, S, Lause, P, Decroly, N, Shoelson, S E, Thissen, J-P

“…Several catabolic states (sepsis, cancer, etc.) associated with acute inflammation are characterized by a loss of skeletal muscle due to accelerated…”
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Myosin light chain kinase controls voltage-dependent calcium channels in vascular smooth muscle by Martinsen, A., Schakman, O., Yerna, X., Dessy, C., Morel, N.

“…The Ca 2+ -dependent kinase myosin light chain kinase (MLCK) is the activator of smooth muscle contraction. In addition, it has been reported to be involved in…”
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Brown Adipose Tissue Stimulation as a New Approach to Fight Obesity and Metabolic Syndrome by Poekes, L, Legry, V, Schakman, O, Bol, A, Farrell, G, Leclercq, I.A

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Role of Akt/GSK-3β/β-Catenin Transduction Pathway in the Muscle Anti-Atrophy Action of Insulin-Like Growth Factor-I in Glucocorticoid-Treated Rats by Schakman, O, Kalista, S, Bertrand, L, Lause, P, Verniers, J, Ketelslegers, J. M, Thissen, J. P

“…Decrease of muscle IGF-I plays a critical role in muscle atrophy caused by glucocorticoids (GCs) because IGF-I gene electrotransfer prevents muscle atrophy…”
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P0919 : Defective thermogenic adaptation to high calorie intake: A contender in NASH pathogenesis in foz/foz mice by Poekes, L, Legry, V, Schakman, O, Bol, A, Farrell, G, Leclercq, I.A

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Insulin-Like Growth Factor-I Gene Transfer by Electroporation Prevents Skeletal Muscle Atrophy in Glucocorticoid-Treated Rats by Schakman, O, Gilson, H, de Coninck, V, Lause, P, Verniers, J, Havaux, X, Ketelslegers, J. M, Thissen, J. P

“…Catabolic states caused by injury are characterized by a loss of skeletal muscle. The anabolic action of IGF-I on muscle and the reduction of its muscle…”
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Adiponectin, a powerful brake on skeletal muscle inflammation and injury by Abou-Samra, M, Lecompte, S, Schakman, O, Noel, L, Lafosse, A, Many, M, Gailly, P, Brichard, S

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Functional assessment of skeletal muscle in intact mice lacking myostatin by concurrent NMR imaging and spectroscopy by Baligand, C, Gilson, H, Ménard, J C, Schakman, O, Wary, C, Thissen, J-P, Carlier, P G

“…Inhibiting myostatin (mstn) causes spectacular increase in muscle mass, spurring research for therapeutic approaches against neuromuscular disorders. Yet,…”
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Mechanisms of glucocorticoid-induced myopathy by Thissen, J.P, Schakman, O, Gilson, H

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G.P.85 Cerebellar dysfunction in the mdx mouse: An electrophysiological and behavioral study by Prigogine, C, Deconinck, N, Ruiz, J. Marquez, Schakman, O, Gailly, P, Cheron, G

“…Abstract Patients with Duchenne muscular dystrophy (DMD), besides a severe muscle impairment caused by the absence of dystrophin expression in skeletal muscle,…”
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M.P.5.02 Evaluating muscle function in mice lacking myostatin by functional nuclear magnetic resonance in vivo: Preliminary results by Baligand, C, Gilson, H, Ménard, J.C, Schakman, O, Wary, C, Thissen, J.P, Carlier, P.G

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O71 Puissance des effets anti-inflammatoires de l’adiponectine sur le muscle squelettique by Abou Samra, M, Schakman, O, Culot, E, Noel, L, Gailly, P, Brichard, S

“…Introduction L’adiponectine, ApN est une adipokine abaissée en cas de syndrome métabolique, ce qui joue un rôle-clef dans la pathogénie de ce syndrome. Nous…”
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OP031 ROLE OF IGF-I AND TNF-ALPHA/NF-KAPPA B PATHWAY IN THE INDUCTION OF THE TRANSCRIPTIONAL MUSCLE ATROPHY PROGRAM BY ACUTE INFLAMMATION by Schakman, O, Dehoux, M, Bouchuari, S, Delaere, S, Lause, P, Decroly, N, Shoelson, S.E, Thissen, J.P

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Administration of adiponectin receptor agonist adiporon relieves cancer cachexia-induced muscle wasting by mitigating inflammation in tumor bearing mice by Massart, I., Kouakou, N., Lause, P., Schakman, O., Loumaye, A., Abou-Samra, M., Bindels, L., Brichard, S., Thissen, J.-P.

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