Search Results - "Schaik, Thijs A."

Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas by Kanaya, Nobuhiko, Kitamura, Yohei, Lopez Vazquez, Maria, Franco, Arnaldo, Chen, Kok-Siong, van Schaik, Thijs A, Farzani, Touraj Aligholipour, Borges, Paulo, Ichinose, Toru, Seddiq, Waleed, Kuroda, Shinji, Boland, Genevieve, Jahan, Nusrat, Fisher, David, Wakimoto, Hiroaki, Shah, Khalid

“…Oncolytic virus therapy has shown activity against primary melanomas; however, its efficacy in brain metastases remains challenging, mainly because of the…”
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High risk of multiple gastric cancers in Japanese individuals with Lynch syndrome by Kanaya, Nobuhiko, Schaik, Thijs A., Aoki, Hideki, Sato, Yumiko, Taniguchi, Fumitaka, Shigeyasu, Kunitoshi, Sugano, Kokichi, Akagi, Kiwamu, Ishida, Hideyuki, Tanakaya, Kohji

“…Aim Lynch syndrome (LS) is a dominantly inherited syndrome characterized by an increased risk for LS associated tumors such as colorectal cancer (CRC) and…”
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Therapy-Induced Tumor Cell Death: Friend or Foe of Immunotherapy? by van Schaik, Thijs A., Chen, Kok-Siong, Shah, Khalid

“…Combinatory treatments using surgery, radiotherapy and/or chemotherapy together with immunotherapy have shown encouraging results for specific subsets of…”
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Engineered cell-based therapies in ex vivo ready-made CellDex capsules have therapeutic efficacy in solid tumors by van Schaik, Thijs A., Moreno-Lama, Lucia, Aligholipour Farzani, Touraj, Wang, Mian, Chen, Kok-Siong, Li, Wanlu, Cai, Ling, Zhang, Yu Shrike, Shah, Khalid

“…Encapsulated cell-based therapies for solid tumors have shown promising results in pre-clinical settings. However, the inability to culture encapsulated…”
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Corrigendum: Establishment and immune phenotyping of patient-derived glioblastoma models in humanized mice by Liu, Longsha, van Schaik, Thijs A, Chen, Kok-Siong, Rossignoli, Filippo, Borges, Paulo, Vrbanac, Vladimir, Wakimoto, Hiroaki, Shah, Khalid

“…[This corrects the article DOI: 10.3389/fimmu.2023.1324618.]…”
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Establishment and immune phenotyping of patient-derived glioblastoma models in humanized mice by Liu, Longsha, van Schaik, Thijs A, Chen, Kok-Siong, Rossignoli, Filippo, Borges, Paulo, Vrbanac, Vladimir, Wakimoto, Hiroaki, Shah, Khalid

“…Glioblastoma (GBM) is the most aggressive and common type of malignant brain tumor diagnosed in adults. Preclinical immunocompetent mouse tumor models…”
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Bifunctional cancer cell-based vaccine concomitantly drives direct tumor killing and antitumor immunity by Chen, Kok-Siong, Reinshagen, Clemens, Van Schaik, Thijs A, Rossignoli, Filippo, Borges, Paulo, Mendonca, Natalia Claire, Abdi, Reza, Simon, Brennan, Reardon, David A, Wakimoto, Hiroaki, Shah, Khalid

“…The administration of inactivated tumor cells is known to induce a potent antitumor immune response; however, the efficacy of such an approach is limited by…”
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Abstract 1816: Locoregional delivery with gene edited and engineered stem cells modulates unique immune profiling in leptomeningeal metastasis by Kanaya, Nobuhiko, Chen, Kok Siong, Kajiwara, Yoshinori, Seddiq, Waleed, van Schaik, Thijs A., Farzani, Touraj Aligholipour, Borges, Paulo, Khalid, Shah

“…Patients with advanced melanoma have a high propensity to metastasize to the brain and numerous investigational treatments with targeted agents have shown…”
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