Search Results - "Schaft, Julia"

Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2 by Lubitz, Sandra, Glaser, Stefan, Schaft, Julia, Stewart, A Francis, Anastassiadis, Konstantinos

“…Epigenetic regulation by histone methyltransferases provides transcriptional memory and inheritable propagation of gene expression patterns. Potentially, the…”
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Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development by Glaser, Stefan, Schaft, Julia, Lubitz, Sandra, Vintersten, Kristina, van der Hoeven, Frank, Tufteland, Katharina R, Aasland, Rein, Anastassiadis, Konstantinos, Ang, Siew-Lan, Stewart, A Francis

“…Epigenesis is the process whereby the daughters of a dividing cell retain a chromatin state determined before cell division. The best-studied cases involve the…”
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Derivation of Human Embryonic Stem Cell Lines from Vitrified Human Blastocysts by Bradley, Cara K, Schaft, Julia, Roy, Tammie K, Dumevska, Biljana, Peura, Teija T

“…Human embryonic stem cells are pluripotent cells typically derived from blastulating embryos that have become excess to clinical needs in assisted reproduction…”
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Derivation of Huntington Disease affected Genea090 human embryonic stem cell line by Dumevska, Biljana, Schaft, Julia, McKernan, Robert, Hu, Jesselyn, Schmidt, Uli

“…The Genea090 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying Htt gene CAG expansion of 45…”
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Derivation of Huntington Disease affected Genea091 human embryonic stem cell line by Dumevska, Biljana, Schaft, Julia, McKernan, Robert, Hu, Jesselyn, Schmidt, Uli

“…The Genea091 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying Htt gene CAG expansion of 40…”
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Derivation of DM2 affected human embryonic stem cell line Genea066 by Dumevska, Biljana, Schaft, Julia, McKernan, Robert, Goel, Divya, Schmidt, Uli

“…The Genea066 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying expansion of CCTG repeats in exon…”
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Derivation of FSHD1 affected human embryonic stem cell line Genea096 by Dumevska, Biljana, Schaft, Julia, McKernan, Robert, Goel, Divya, Schmidt, Uli

“…The Genea096 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying a deletion in 4q35 with only 6…”
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A reliable lacZ expression reporter cassette for multipurpose, knockout-first alleles by Testa, Giuseppe, Schaft, Julia, van der Hoeven, Frank, Glaser, Stefan, Anastassiadis, Konstantinos, Zhang, Youming, Hermann, Thomas, Stremmel, Wolfgang, Stewart, A. Francis

“…Alteration of the mouse genome through homologous recombination in embryonic stem (ES) cells is the most accurate and versatile way to dissect gene function in…”
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Supporting a vibrant entrepreneurial ecosystem by Schaft, Julia, Füller, Stephanie

“…Graphical Abstract How do you create a vibrant entrepreneurial life science ecosystem? How research communities in the Rhine‐Main‐Neckar region around…”
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Derivation of human embryonic stem cell lines from vitrified human embryos by Peura, Teija T, Schaft, Julia, Stojanov, Tomas

“…Human embryonic stem cell lines are usually derived from human embryos that have become excess to clinical needs in assisted reproduction programs, whether…”
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Efficient FLP recombination in mouse ES cells and oocytes by Schaft, Julia, Ashery-Padan, Ruth, van der Hoeven, Frank, Gruss, Peter, Stewart, A. Francis

“…We report an improved vector, pCAGGS‐FLPe, for transient expression of the enhanced FLP recombinase in mouse ES cells and oocytes. In standard transfection…”
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Supporting a vibrant entrepreneurial ecosystem: High density, critical mass, and effective strategies underpin the success of innovative life science ecosystems by Schaft, Julia, Füller, Stephanie

“…How do you create a vibrant entrepreneurial life science ecosystem? How research communities in the Rhine-Main-Neckar region around Heidelberg have grown and…”
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Generation of human embryonic stem cells by Peura, Teija, Schaft, Julia, Dumevska, Biljana, Stojanov, Tomas

“…This unit describes generation of human embryonic stem cell lines from early human embryos. The focus is on actual handling of embryos and early embryonic…”
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