Search Results - "Schaffter, Lisa M."

Scalable Synthesis and Isolation of the Four Stereoisomers of Methyl 1-Amino-3-(4-bromophenyl)cyclopentanecarboxylate, Useful Intermediates for the Synthesis of S1P1 Receptor Agonists by Wallace, Grier A, Gordon, Thomas D, Hayes, Martin E, Konopacki, Donald B, Fix-Stenzel, Shannon R, Zhang, Xiaolei, Grongsaard, Pintipa, Cusack, Kevin P, Schaffter, Lisa M, Henry, Rodger F, Stoffel, Robert H

“…The individual isomers of methyl 1-amino-3-(4-bromophenyl)cyclopentanecarboxylate are useful intermediates for the synthesis of S1P1 receptor agonists. Herein…”
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Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design by Hobson, Adrian D, Judge, Russell A, Aguirre, Ana L, Brown, Brian S, Cui, Yifang, Ding, Ping, Dominguez, Eric, DiGiammarino, Enrico, Egan, David A, Freiberg, Gail M, Gopalakrishnan, Sujatha M, Harris, Christopher M, Honore, Marie P, Kage, Karen L, Kapecki, Nicolas J, Ling, Christopher, Ma, Junli, Mack, Helmut, Mamo, Mulugeta, Maurus, Stefan, McRae, Bradford, Moore, Nigel S, Mueller, Bernhard K, Mueller, Reinhold, Namovic, Marian T, Patel, Kaushal, Pratt, Steve D, Putman, C. Brent, Queeney, Kara L, Sarris, Kathy K, Schaffter, Lisa M, Stoll, Vincent, Vasudevan, Anil, Wang, Lei, Wang, Lu, Wirthl, William, Yach, Kimberly

“…A HTS campaign identified compound 1, an excellent hit-like molecule to initiate medicinal chemistry efforts to optimize a dual ROCK1 and ROCK2 inhibitor…”
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A stereoselective and scalable synthesis of a conformationally constrained S1P1 agonist by Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.

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Effects of Matrix Structure/Acidity on Ion Formation in Matrix-Assisted Laser Desorption Ionization Mass Spectrometry by Gimon-Kinsel, Mary, Preston-Schaffter, Lisa M, Kinsel, Gary R, Russell, David H

“…The involvement of ground and excited state proton transfer reactions in matrix-assisted laser desorption ionization (MALDI) of bradykinin and bovine insulin…”
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Open access MS : A walk-up MS service by SPREEN, R. C, SCHAFFTER, L. M

“…A mass spectrometry system that is easy for nonspectrometrists to use can provide data that improve efficiency and productivity. Russell and Schaffter discuss…”
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Effects of heavy-atom substituents on matrices used for matrix-assisted laser desorption-ionization mass spectrometry by Preston-Schaffter, Lisa M., Kinsel, Gary R., Russell, D.H.

“…The data reported show that heavy-atom substitution on matrices that are used for matrix-assisted laser desorption-ionization mass spectrometry enhance [M + H]…”
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MALDI-MS as a monitor of the purification and folding of synthetic eclosion hormone by Wang, Y J, Yurttas, L, Dale, B E, Russell, D H, Kinsel, G, Preston-Schaffter, L M, Johnson, V, Hayes, T K

“…Analogues of the small protein Manduca sexta eclosion hormone (62 amino acids) were synthesized by Fmoc solid-phase methodology. Matrix-assisted laser…”
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A stereoselective and scalable synthesis of a conformationally constrained S1P 1 agonist by Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.

“…A scalable and enantioselective synthesis of a potent S1P 1 agonist containing two stereogenic centers on a cyclopentane ring is described. Control of the…”
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Peer Reviewed: Open Access MS: A Walk-up MS Service by SPREEN, Russell C., SCHAFFTER, Lisa M.

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Peer Reviewed: Open Access MS: A Walk-up MS Service: An MS system that is easy for nonspectrometrists to use can provide data that improve efficiency and productivity by Spreen, Russell C, Schaffter, Lisa M

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