Search Results - "Schaffer, Kirsten"

Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: Towards a common nomenclature by Bender, Jennifer K., Cattoir, Vincent, Hegstad, Kristin, Sadowy, Ewa, Coque, Teresa M., Westh, Henrik, Hammerum, Anette M., Schaffer, Kirsten, Burns, Karen, Murchan, Stephen, Novais, Carla, Freitas, Ana R., Peixe, Luísa, Del Grosso, Maria, Pantosti, Annalisa, Werner, Guido

“…Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE infections are difficult to treat since common therapeutic options…”
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Hypoxia Increases Antibiotic Resistance in Pseudomonas aeruginosa through Altering the Composition of Multidrug Efflux Pumps by Schaible, Bettina, Taylor, Cormac T, Schaffer, Kirsten

“…Antibiotic resistance is a significant and developing problem in general medical practice and a common clinical complication in cystic fibrosis patients…”
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Genomic Analysis of Mycobacterium abscessus Complex Isolates Collected in Ireland between 2006 and 2017 by Redondo, Natalia, Mok, Simone, Montgomery, Lorraine, Flanagan, Peter R, McNamara, Eleanor, Smyth, Edmond G, O'Sullivan, Niamh, Schaffer, Kirsten, Rogers, Thomas R, Fitzgibbon, Margaret M

“…Members of the complex (MABC) are multidrug-resistant nontuberculous mycobacteria and cause opportunistic pulmonary infections in individuals with cystic…”
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Terrisporobacter hibernicus sp. nov., isolated from bovine faeces in Northern Ireland by Mitchell, Molly, Nguyen, Scott V, Connor, Mairead, Fairley, Derek J, Donoghue, Orla, Marshall, Helina, Koolman, Leonard, McMullan, Geoff, Schaffer, Kirsten E, McGrath, John W, Fanning, Séamus

“…A new species of , a Gram-positive, spore-forming anaerobic group, proposed name sp. nov., was isolated in Northern Ireland from bovine faeces collected in…”
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Hypoxia modulates infection of epithelial cells by Pseudomonas aeruginosa by Schaible, Bettina, McClean, Siobhán, Selfridge, Andrew, Broquet, Alexis, Asehnoune, Karim, Taylor, Cormac T, Schaffer, Kirsten

“…Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen commonly associated with lung and wound infections. Hypoxia is a frequent feature of the…”
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Immunoproteomic analysis of proteins expressed by two related pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during human infection by Shinoy, Minu, Dennehy, Ruth, Coleman, Lorraine, Carberry, Stephen, Schaffer, Kirsten, Callaghan, Máire, Doyle, Sean, McClean, Siobhán

“…Burkholderia cepacia complex (Bcc) is an opportunistic bacterial pathogen that causes chronic infections in people with cystic fibrosis (CF). It is a highly…”
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A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis by O'Connor, Andrew, Jurado‐Martín, Irene, Mysior, Margaritha M., Manzira, Anotidaishe L., Drabinska, Joanna, Simpson, Jeremy C., Lucey, Mary, Schaffer, Kirsten, Berisio, Rita, McClean, Siobhán

“…Universal stress proteins (USPs) are ubiquitously expressed in bacteria, archaea, and eukaryotes and play a lead role in adaptation to environmental…”
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Increased Virulence of Bloodstream Over Peripheral Isolates of P. aeruginosa Identified Through Post-transcriptional Regulation of Virulence Factors by Hickey, Caitríona, Schaible, Bettina, Nguyen, Scott, Hurley, Daniel, Srikumar, Shabarinath, Fanning, Séamus, Brown, Eric, Crifo, Bianca, Matallanas, David, McClean, Siobhán, Taylor, Cormac T, Schaffer, Kirsten

“…The factors influencing the virulence of in the development of invasive infection remain poorly understood. Here, we investigated the role of the host…”
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impact of hypoxia on bacterial infection by Schaffer, Kirsten, Taylor, Cormac T

“…Tissue hypoxia is a common microenvironmental feature during inflammation associated with bacterial infection. Hypoxia has recently been shown to play an…”
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Whole-genome Sequencing to Track Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission in Nosocomial Outbreaks by Lucey, Mary, Macori, Guerrino, Mullane, Niamh, Sutton-Fitzpatrick, Una, Gonzalez, Gabriel, Coughlan, Suzie, Purcell, Aisling, Fenelon, Lynda, Fanning, Séamus, Schaffer, Kirsten

“…Abstract Background During the first wave of the coronavirus disease 2019 (COVID-19) pandemic, outbreaks of severe acute respiratory syndrome coronavirus 2…”
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The putative bacterial oxygen sensor Pseudomonas prolyl hydroxylase (PPHD) suppresses antibiotic resistance and pathogenicity in Pseudomonas aeruginosa by Schaible, Bettina, Crifo, Bianca, Schaffer, Kirsten, Taylor, Cormac T.

“…Pseudomonas aeruginosa is an extracellular opportunistic bacterial pathogen commonly associated with infectious complications in susceptible individuals, such…”
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Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium by Bryant, Josephine M., Grogono, Dorothy M., Rodriguez-Rincon, Daniela, Everall, Isobel, Brown, Karen P., Moreno, Pablo, Verma, Deepshikha, Hill, Emily, Drijkoningen, Judith, Gilligan, Peter, Esther, Charles R., Noone, Peadar G., Giddings, Olivia, Bell, Scott C., Thomson, Rachel, Wainwright, Claire E., Coulter, Chris, Pandey, Sushil, Wood, Michelle E., Stockwell, Rebecca E., Ramsay, Kay A., Sherrard, Laura J., Kidd, Timothy J., Jabbaur, Nassib, Johnson, Graham R., Knibbs, Luke D., Morawska, Lidia, Sly, Peter D., Jones, Andrew, Bilton, Diana, Laurenson, Ian, Ruddy, Michael, Bourke, Stephen, Bowler, Ian C. J. W., Chapman, Stephen J., Clayton, Andrew, Cullen, Mairi, Dempsey, Owen, Denton, Miles, Desai, Maya, Drew, Richard J., Edenborough, Frank, Evans, Jason, Folb, Jonathan, Daniels, Thomas, Humphrey, Helen, Isalska, Barbara, Jensen-Fangel, Søren, Jönsson, Bodil, Jones, Andrew M., Katzenstein, Terese L., Lillebaek, Troels, MacGregor, Gordon, Mayell, Sarah, Millar, Michael, Modha, Deborah, Nash, Edward F., O'Brien, Christopher, O'Brien, Deirdre, Ohri, Chandra, Pao, Caroline S., Peckham, Daniel, Perrin, Felicity, Perry, Audrey, Pressler, Tania, Prtak, Laura, Qvist, Tavs, Robb, Ali, Rodgers, Helen, Schaffer, Kirsten, Shafi, Nadia, van Ingen, Jakko, Walshaw, Martin, Watson, Danie, West, Noreen, Whitehouse, Joanna, Haworth, Charles S., Harris, Simon R., Ordway, Diane, Parkhill, Julian, Floto, R. Andres

“…Lung infections with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous mycobacteria, are emerging as an important global threat to…”
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A Core Genome Multilocus Sequence Typing Scheme for Enterococcus faecalis by Neumann, Bernd, Prior, Karola, Bender, Jennifer K, Harmsen, Dag, Klare, Ingo, Fuchs, Stephan, Bethe, Astrid, Zühlke, Daniela, Göhler, André, Schwarz, Stefan, Schaffer, Kirsten, Riedel, Katharina, Wieler, Lothar H, Werner, Guido

“…Among enterococci, occurs ubiquitously, with the highest incidence of human and animal infections. The high genetic plasticity of complicates both molecular…”
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The putative bacterial oxygen sensor Pseudomonas prolyl hydroxylase (PPHD) suppresses antibiotic resistance and pathogenicity in Pseudomonas aeruginosa by Schaible, Bettina, Crifo, Bianca, Schaffer, Kirsten, Taylor, Cormac T.

“…Pseudomonas aeruginosa is an extracellular opportunistic bacterial pathogen commonly associated with infectious complications in susceptible individuals, such…”
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Hypoxia, innate immunity and infection in the lung by Schaible, Bettina, Schaffer, Kirsten, Taylor, Cormac T

“…Abstract The mucosal surface of the lung is the key interface between the external atmosphere and the bloodstream. Normally, this well oxygenated tissue is…”
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Sequential Burkholderia cenocepacia Isolates from Siblings with Cystic Fibrosis Show Increased Lung Cell Attachment by Cullen, Louise, O'Connor, Andrew, Drevinek, Pavel, Schaffer, Kirsten, McClean, Siobhán

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Whole-genome sequencing to track SARS-CoV-2 transmission in nosocomial outbreaks by Lucey, Mary, Macori, Guerrino, Mullane, Niamh, Sutton-Fitzpatrick, Una, Gonzalez, Gabriel, Coughlan, Suzie, Purcell, Aisling, Fenelon, Lynda, Fanning, Séamus, Schaffer, Kirsten

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Yersinia canariae sp. nov., isolated from a human yersiniosis case by Nguyen, Scott V, Greig, David R, Hurley, Daniel, Donoghue, Orla, Cao, Yu, McCabe, Evonne, Mitchell, Molly, Schaffer, Kirsten, Jenkins, Claire, Fanning, Séamus

“…A Gram-negative rod from the genus was isolated from a clinical case of yersiniosis in the United Kingdom. Long read sequencing data from an Oxford Nanopore…”
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Yersinia hibernica sp. nov., isolated from pig-production environments by Nguyen, Scott V, Muthappa, Dechamma Mundanda, Hurley, Daniel, Donoghue, Orla, McCabe, Evonne, Anes, João, Schaffer, Kirsten, Murphy, Brenda P, Buckley, Jim F, Fanning, Séamus

“…A Gram-stain-negative, rod-shaped strain isolated from pig-production environments was identified as a new species within the genus Yersinia using multifaceted…”
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Hypoxia Reduces the Pathogenicity of Pseudomonas aeruginosa by Decreasing the Expression of Multiple Virulence Factors by Schaible, Bettina, Rodriguez, Javier, Garcia, Amaya, von Kriegsheim, Alexander, McClean, Siobhán, Hickey, Caitríona, Keogh, Ciara E., Brown, Eric, Schaffer, Kirsten, Broquet, Alexis, Taylor, Cormac T.

“…Our understanding of how the course of opportunistic bacterial infection is influenced by the microenvironment is limited. We demonstrate that the…”
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