Search Results - "Schaffer, Jeremy E."

Enzyme Prodrug Therapy Achieves Site-Specific, Personalized Physiological Responses to the Locally Produced Nitric Oxide by Winther, Anna K, Fejerskov, Betina, ter Meer, Marja, Jensen, Najah B.S, Dillion, Ross, Schaffer, Jeremy E, Chandrawati, Rona, Stevens, Molly M, Schultze Kool, Leo J, Simonsen, Ulf, Zelikin, Alexander N

“…Nitric oxide (NO) is a highly potent but short-lived endogenous radical with a wide spectrum of physiological activities. In this work, we developed an…”
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Structure-Property Relationships in Conventional and Nanocrystalline NiTi Intermetallic Alloy Wire by Schaffer, Jeremy E.

“…Homogeneous 177-μm diameter nanocrystalline Nitinol wires were produced and compared to microcrystalline Nitinol from equivalent ingot stock. Property…”
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Radiopaque FeMnN-Mo composite drawn filled tubing wires for braided absorbable neurovascular devices by Griebel, Adam J., Maier, Petra, Summers, Henry, Clausius, Benjamin, Kanasty, Isabella, He, Weilue, Peterson, Nicholas, Czerniak, Carolyn, Oliver, Alexander A., Kallmes, David F., Kadirvel, Ramanathan, Schaffer, Jeremy E., Guillory, Roger J.

“…Flow diverter devices are small stents used to divert blood flow away from aneurysms in the brain, stagnating flow and inducing intra-aneurysmal thrombosis…”
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Large Dimension and Low-Cost Fe-SMA Rods by Ozcan, Hande, Ma, Ji, Schaffer, Jeremy E., Karaman, Ibrahim

“…The effects on sample size on abnormal grain growth in inexpensive FeMnAlNi shape memory alloy (SMAs) wires and rod were investigated. It was shown that…”
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Cold-Drawn Bioabsorbable Ferrous and Ferrous Composite Wires: An Evaluation of Mechanical Strength and Fatigue Durability by Schaffer, Jeremy E., Nauman, Eric A., Stanciu, Lia A.

“…Yield strengths exceeding 1 GPa with elastic strains exceeding 1 pct were measured in novel bioabsorbable wire materials comprising high-purity iron (Fe),…”
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Aging Enhanced Super-Elasticity and Ductility of a Cold NiTiTa Alloy by Cai, Song, Schaffer, Jeremy E., Ren, Yang

“…A cold NiTiTa alloy was found to be very brittle in the fully annealed condition due to its high-austenite stability, which suppressed…”
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Intraluminal Flow Diverter Design Primer for Neurointerventionalists by Oliver, Alexander A, Senol, Yigit Can, Bilgin, Cem, Schaffer, Jeremy E, Kadirvel, Ramanathan, Kallmes, David F, Wainwright, John M

“…The clinical use of flow diverters for the treatment of intracranial aneurysms has rapidly grown. Consequently, the market and technology for these devices has…”
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Benchtop proof of concept and comparison of iron- and magnesium-based bioresorbable flow diverters by Oliver, Alexander A, Bilgin, Cem, Vercnocke, Andrew J, Carlson, Kent D, Kadirvel, Ramanathan, Guillory, Roger J, Griebel, Adam J, Schaffer, Jeremy E, Dragomir-Daescu, Dan, Kallmes, David F

“…Bioresorbable flow diverters (BRFDs) could significantly improve the performance of next-generation flow diverter technology. In the current work, magnesium…”
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Cold drawn bioabsorbable ferrous and ferrous composite wires: An evaluation of in vitro vascular cytocompatibility by Schaffer, Jeremy E., Nauman, Eric A., Stanciu, Lia A.

“…A systematic approach is applied to quantify the impact of bioabsorbable metals on human vascular endothelial cells (EC) and aortic smooth muscle cells (SMC)…”
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Discovery of a 〈2 1 0〉-fiber texture in medical-grade metastable beta titanium wire by Cai, Song, Schaffer, Jeremy E., Ren, Yang, Daymond, Mark R.

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Discovery of a 210-fiber texture in medical-grade metastable beta titanium wire by Cai, Song, Schaffer, Jeremy E, Ren, Yang, Daymond, Mark R

“…The texture and phase evolution of metastable beta -III Ti alloy wires, produced in a medical-grade wire-processing facility, are examined via synchrotron…”
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An in vitro and in vivo characterization of fine WE43B magnesium wire with varied thermomechanical processing conditions by Griebel, Adam J, Schaffer, Jeremy E, Hopkins, Tracy M, Alghalayini, Alaa, Mkorombindo, Tinomudaishe, Ojo, Kolade O, Xu, Zhigang, Little, Kevin J, Pixley, Sarah K

“…Absorbable implants made of magnesium alloys may revolutionize surgical intervention, and fine magnesium wire will be critical to many applications…”
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Magnetically Inserted Neural Electrodes: Tissue Response and Functional Lifetime by Dryg, Ian D., Ward, Matthew P., Qing, Kurt Y., Mei, Henry, Schaffer, Jeremy E., Irazoqui, Pedro P.

“…Neural recording and stimulation have great clinical potential. Long-term neural recording remains a challenge, however, as implantable electrodes eventually…”
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Fatigue, Fracture, and Crack Arrest from Bending Induced Pre-strain in Superelastic Nitinol by Malito, Louis G., Briant, Paul L., Bowers, Matthew L., Easley, Sarah, Schaffer, Jeremy E., James, Brad

“…The present study evaluates the fatigue and fracture performance of electropolished Nitinol wire apex specimens subjected to a range of initial bending…”
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Fatigue Performance of Nitinol Round Wire with Varying Cold Work Reductions by Schaffer, Jeremy E., Plumley, David L.

“…The role of cold work reduction and its effect on fatigue properties are examined by means of rotary beam fatigue testing. In this study, processing parameters…”
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Continuously Grooved Stent Struts for Enhanced Endothelial Cell Seeding by ter Meer, Marja, Daamen, Willeke F., Hoogeveen, Yvonne L., van Son, Gijs J. F., Schaffer, Jeremy E., van der Vliet, J. Adam, Kool, Leo J. Schultze, van den Heuvel, Lambertus P.

“…Purpose Implantation of pre-endothelialized stents could enhance cellular recovery of a damaged vessel wall provided attached cells remain viable, functional…”
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Taming the Pseudoelastic Response of Nitinol Using Ion Implantation by Hinojos, Alejandro, Hong, Daniel, Sriram, Hariharan, Feng, Longsheng, Yang, Chao, Wharry, Janelle P., Gao, Xuesong, Hattar, Khalid, Li, Nan, Schaffer, Jeremy E., Wang, Yunzhi, Mills, Michael J., Anderson, Peter M.

“…Implantation of Ni50.5Ti49.5 wire with 30 MeV Ni6+ ions at doses (< 0.1 DPA) typically smaller than employed in the literature is shown to systematically alter…”
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Nanocrystalline material with gigacycle fatigue life by Schaffer, Jeremy E

“…A processing technology has been developed that can be applied to many different fine wire medical alloys to improve their fatigue properties. This technology…”
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Mechanical Conditioning of Superelastic Nitinol Wire for Improved Fatigue Resistance by Schaffer, Jeremy E.

“…Metallic wire used in medical devices contains small defects that must be accounted for in design to guard against failure. Sites of probable failure are often…”
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An Examination of Fatigue Initiation Mechanisms in Thin 35Co-35Ni-20Cr-10Mo Medical Grade Wires by Schaffer, Jeremy E.

“…Knowledge of the intrinsic defect size distribution, surface grain size distribution, and prior deformation history are important factors in determining…”
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