Search Results - "Schafer, Jamie L."
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Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides
Published in PLoS pathogens (01-09-2015)“…Natural killer (NK) cell responses in primates are regulated in part through interactions between two highly polymorphic molecules, the killer-cell…”
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2
Antigen-specific NK cell memory in rhesus macaques
Published in Nature immunology (01-09-2015)“…Recent studies have shown features of antigen-specific memory in mouse NK cells, but it is unclear whether this phenomenon also exists in primates. Barouch and…”
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Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy
Published in Journal of virology (01-07-2015)“…Recent evidence suggests that even in treated infections, human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replication may continue…”
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Monocyte subsets exhibit transcriptional plasticity and a shared response to interferon in SIV‐infected rhesus macaques
Published in Journal of leukocyte biology (01-01-2018)“…The progression to AIDS is influenced by changes in the biology of heterogeneous monocyte subsets. Classical (CD14++CD16–), intermediate (CD14++CD16+), and…”
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Selection of an HLA-C03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa
Published in PLoS medicine (01-11-2015)“…Viruses can evade immune surveillance, but the underlying mechanisms are insufficiently understood. Here, we sought to understand the mechanisms by which…”
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SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage
Published in The Journal of infectious diseases (01-02-2016)“…Disruption of the mucosal epithelium during lentivirus infections permits translocation of microbial products into circulation, causing immune activation and…”
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KIR3DL01 recognition of Bw4 ligands in the rhesus macaque: maintenance of Bw4 specificity since the divergence of apes and Old World monkeys
Published in The Journal of immunology (1950) (15-02-2014)“…The identification of MHC class I ligands for rhesus macaque killer cell Ig-like receptors (KIRs) is fundamental to our basic understanding of KIR and MHC…”
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Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C03: 04 and modulate primary natural killer cell function
Published in AIDS (London) (19-06-2014)“…OBJECTIVE:The aim of this study was to assess the consequence of sequence variations in HLA-C03:04-presented HIV-1 p24 Gag epitopes on binding of the…”
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9
NK cell exhaustion: bad news for chronic disease?
Published in Oncotarget (08-09-2015)“…Natural killer (NK) cells are generally considered as the effector arm of nonspecific innate immunity, providing rapid recognition and lysis of virus-infected…”
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Abstract 4972: Preclinical development of a first-in-class NKp30xBCMA NK cell engager for the treatment of multiple myeloma
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Multiple myeloma (MM) is characterized by clonal expansion of malignant plasma cells. Although several new drugs for the treatment of MM have greatly improved…”
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Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides: e1005145
Published in PLoS pathogens (01-09-2015)“…Natural killer (NK) cell responses in primates are regulated in part through interactions between two highly polymorphic molecules, the killer-cell…”
Get full text
Journal Article -
12
Suppression of a natural killer cell response by simian immunodeficiency virus peptides
Published in PLoS pathogens (01-09-2015)“…Natural killer (NK) cell responses in primates are regulated in part through interactions between two highly polymorphic molecules, the killer-cell…”
Get full text
Journal Article -
13
Selection of an [HLA-C.sup.]03:04-restricted HIV-1 p24 gag sequence variant is associated with viral escape from KIR2DL3+ natural killer cells: data from an observational cohort in South Africa
Published in PLoS medicine (01-11-2015)“…Background Viruses can evade immune surveillance, but the underlying mechanisms are insufficiently understood. Here, we sought to understand the mechanisms by…”
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Journal Article -
14
Selection of an HLA-C03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa: e1001900
Published in PLoS medicine (01-11-2015)“…Background Viruses can evade immune surveillance, but the underlying mechanisms are insufficiently understood. Here, we sought to understand the mechanisms by…”
Get full text
Journal Article