Search Results - "Schaer, T."

The role of the nucleus pulposus in intervertebral disc recovery: Towards improved specifications for nucleus replacement devices by Raftery, K., Rahman, T., Smith, N., Schaer, T., Newell, N.

“…Nucleus replacement devices (NRDs) have potential to treat degenerated or herniated intervertebral discs (IVDs). However, IVD height loss is a post-treatment…”
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Preclinical animal models in single site cartilage defect testing: a systematic review by Ahern, B.J, Parvizi, J, Boston, R, Schaer, T.P

“…Summary Objective Review the literature for single site cartilage defect research and evaluate the respective strengths and weaknesses of different preclinical…”
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In vitro investigations of Staphylococcus aureus biofilms in physiological fluids suggest that current antibiotic delivery systems may be limited by Isguven, S, Fitzgerald, K, Delaney, L J, Harwood, M, Schaer, T P, Hickok, N J

“…Orthopaedic surgical site infections, especially when a hardware is involved, are associated with biofilm formation. Clinical strategies for biofilm…”
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A large animal model that recapitulates the spectrum of human intervertebral disc degeneration by Gullbrand, S.E, Malhotra, N.R, Schaer, T.P, Zawacki, Z, Martin, J.T, Bendigo, J.R, Milby, A.H, Dodge, G.R, Vresilovic, E.J, Elliott, D.M, Mauck, R.L, Smith, L.J

“…Summary Objective The objective of this study was to establish a large animal model that recapitulates the spectrum of intervertebral disc degeneration that…”
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Intervertebral disc degeneration instigates vertebral endplate remodeling and facet joint pathology in a large animal model by Gullbrand, SE, Orozco, BS, Fainor, M, Meadows, K, Hilliard, R, Boyes, M, Mahindroo, S, Mauck, RL, Elliott, DM, Schaer, TP, Smith, HE

“…Although the intervertebral discs are the most studied region of the spinal motion segment with respect to their degeneration and contributions to back pain,…”
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Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors by Lyukmanova, E. N., Shulepko, M. A., Shenkarev, Z. O., Bychkov, M. L., Paramonov, A. S., Chugunov, A. O., Kulbatskii, D. S., Arvaniti, M., Dolejsi, Eva, Schaer, T., Arseniev, A. S., Efremov, R. G., Thomsen, M. S., Dolezal, V., Bertrand, D., Dolgikh, D. A., Kirpichnikov, M. P.

“…Human-secreted Ly-6/uPAR-related protein-2 (SLURP-2) regulates the growth and differentiation of epithelial cells. Previously, the auto/paracrine activity of…”
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Molecular engineering of an orthopaedic implant: from bench to bedside by Shapiro, I M, Hickok, N J, Parvizi, J, Stewart, S, Schaer, T P

“…The use of metallic implants has revolutionised the practice of orthopaedic surgery. While the safety and biocompatibility of these devices are excellent, a…”
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Intravenous technetium-99m labelled PEG-liposomes in horses: A safety and biodistribution study by UNDERWOOD, C., VAN EPS, A. W., ROSS, M. W., LAVERMAN, P., VAN BLOOIS, L., STORM, G., SCHAER, T. P.

“…Summary Reasons for performing study: Liposomes are phospholipid nanoparticles that extravasate at sites of increased vascular permeability. They have…”
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Arthroscopy of the normal cadaveric ovine femorotibial joint: a systematic approach to the cranial and caudal compartments by Modesto, R B, Mansmann, K A, Schaer, T P

“…Preclinical studies using large animal models play an intergral part in translational research. For this study, our objectives were: to develop and validate…”
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Proximal interphalangeal arthrodesis in 22 horses by SCHAER, T. P., BRAMLAGE, L. R., EMBERTSON, R. M., HANCE, S.

“…Summary The purpose of this study was to evaluate a new method of internal fixation technique for pastern arthrodesis. Pastern arthrodeses are performed…”
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Conservative management of 17 horses with nonarticular fractures of the tibial tuberosity by ARNOLD, C. E., SCHAER, T. P., BAIRD, D. L., MARTIN, B. B.

“…Summary Reasons for performing study: Fractures of the tibial tuberosity (FTT) are caused by direct trauma, and are the second most commonly reported injury in…”
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Pneumopericardium in a horse secondary to sternal bone marrow aspiration by Durando, M. M., Zarucco, L., Schaer, T. P., Ross, M., Reef, V. B.

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Disseminated blastomycosis in a miniature horse by Dolente, B. A., Habecker, P., Chope, K., MacGillivray, K., Schaer, T.

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Cancer screening in the elderly

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Elder abuse--case studies by Schaer, T

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VANCO Trial—Preliminary Results on the Safety Profile of Intrawound Vancomycin Powder in Complex Spine Surgery by Schär, Ralph T., Zimmerli, Stefan

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How safe are elective craniotomies in elderly patients in neurosurgery today? A prospective cohort study of 1452 consecutive cases by Schär, Ralph T, Tashi, Shpend, Branca, Mattia, Söll, Nicole, Cipriani, Debora, Schwarz, Christa, Pollo, Claudio, Schucht, Philippe, Ulrich, Christian T, Beck, Jürgen, Z'Graggen, Werner J, Raabe, Andreas

“…With global aging, elective craniotomies are increasingly being performed in elderly patients. There is a paucity of prospective studies evaluating the impact…”
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Improvement of health-related quality of life after closure of spinal CSF leaks in patients with spontaneous intracranial hypotension by Jesse, Christopher Marvin, Schär, Ralph T, Petutschnigg, Thomas, Goldberg, Johannes, Dobrocky, Tomas, Piechowiak, Eike Immo, Schankin, Christoph J, Sintonen, Harri, Raabe, Andreas, Häni, Levin

“…Spontaneous intracranial hypotension (SIH) is an important cause of orthostatic headaches caused by spinal CSF leaks. It has a strong negative impact on…”
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Negligible Systemic Uptake of Suprafascial Vancomycin Powder Following Instrumented Posterior Spinal Fusion-Preliminary Results From A Randomized Clinical Trial (VANCO Trial) by Schär, Ralph T, Jesse, C Marvin, Montalbetti, Matteo, Söll, Nicole, Lutz, Katharina, Steinsiepe, Valentin, Branca, Mattia, Raabe, Andreas, Zimmerli, Stefan

“…Intrawound vancomycin powder is an emerging strategy to reduce surgical site infections (SSIs) in spine surgery. However, there are concerns relating to its…”
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Functional Outcome in Spinal Meningioma Surgery and Use of Intraoperative Neurophysiological Monitoring by Jesse, Christopher Marvin, Alvarez Abut, Pablo, Wermelinger, Jonathan, Raabe, Andreas, Schär, Ralph T, Seidel, Kathleen

“…Data on intraoperative neurophysiological monitoring (IOM) during spinal meningioma (SM) surgery are scarce. The aim of this study was to assess the role of…”
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