Search Results - "Schaeper, U."
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Delivery of Therapeutic siRNA to the Lung Endothelium via Novel Lipoplex Formulation DACC
Published in Molecular therapy (01-04-2014)“…Posttranscriptional gene silencing by RNA interference can be therapeutically exploited to inhibit pathophysiological gene expression. However, in contrast to…”
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Molecular Cloning and Characterization of a Cellular Phosphoprotein that Interacts with a Conserved C-Terminal Domain of Adenovirus E1A Involved in Negative Modulation of Oncogenic Transformation
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-1995)“…The adenovirus type 2/5 E1A proteins transform primary baby rat kidney (BRK) cells in cooperation with the activated Ras (T24 ras) oncoprotein. The N-terminal…”
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A region in the C‐terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24‐ras mediated transformation, tumorigenesis and metastasis
Published in The EMBO journal (01-02-1993)“…We have examined a series of small deletion mutants within exon 2 of the adenovirus 2/5 E1A oncogene product, the 243R protein, for immortalization, ras…”
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Topic: AS04-MDS Biology and Pathogenesis/AS04c-MDS Mouse models (GEMMS, PDX): CORRECTING DYSREGULATED IRON METABOLISM IN A MURINE MODEL OF MDS
Published in Leukemia research (01-05-2023)Get full text
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Coupling of Gab1 to c-Met, Grb2, and Shp2 Mediates Biological Responses
Published in The Journal of cell biology (26-06-2000)“…Gab1 is a substrate of the receptor tyrosine kinase c-Met and involved in c-Met-specific branching morphogenesis. It associates directly with c-Met via the…”
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Essential Role of Gab1 for Signaling by the c-Met Receptor in Vivo
Published in The Journal of cell biology (18-09-2000)“…The docking protein Gab1 binds phosphorylated c-Met receptor tyrosine kinase directly and mediates signals of c-Met in cell culture. Gab1 is phosphorylated by…”
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The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway
Published in Molecular and Cellular Biology (01-07-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Interaction between a Cellular Protein That Binds to the C-terminal Region of Adenovirus E1A (CtBP) and a Novel Cellular Protein Is Disrupted by E1A through a Conserved PLDLS Motif
Published in The Journal of biological chemistry (10-04-1998)“…Adenovirus E1A proteins immortalize primary animal cells and cooperate with several other oncogenes in oncogenic transformation. These activities are primarily…”
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Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
Published in Cell (21-10-1994)“…Adenovirus E1B 19 kDa protein protects against cell death induced by viral infection and certain external stimuli. The Bcl-2 protein can functionally…”
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Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKL
Published in The Journal of biological chemistry (14-04-2000)“…Hepatocyte growth factor (HGF; scatter factor) is a multipotent protein with mitogenic, motogenic, and developmental functions. Upon activation, the…”
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The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif
Published in Oncogene (01-03-2001)“…The adapter Grb2 is an important mediator of normal cell proliferation and oncogenic signal transduction events. It consists of a central SH2 domain flanked by…”
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Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors
Published in Blood (15-06-2004)“…Erythropoietin (EPO) is required for cell survival during differentiation and for progenitor expansion during stress erythropoiesis. Although signaling…”
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Blutgruppenbestimmung an historischem Knochenmaterial. Zur Problematik der Paläoserologie
Published in Wurzburger medizinhistorische Mitteilungen (1987)Get more information
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The Algebra of the Energy-Momentum Tensor and the Noether Currents in Classical Non-Linear Sigma Models
Published 23-10-1992“…Commun. Math. Phys. 159 (1994) 319-328 The recently derived current algebra of classical non-linear sigma models on arbitrary Riemannian manifolds is extended…”
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Current Algebra of Classical Non-Linear Sigma Models
Published 13-01-1992“…Commun. Math. Phys. 146 (1992) 397-402 The current algebra of classical non-linear sigma models on arbitrary Riemannian manifolds is analyzed. It is found that…”
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The Lie-Poisson Structure of Integrable Classical Non-Linear Sigma Models
Published 23-01-1992“…Commun.Math.Phys. 152 (1993) 167-190 The canonical structure of classical non-linear sigma models on Riemannian symmetric spaces, which constitute the most…”
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Determination of superoxide dismutase (EC 1.15.1.1.) in blood and other tissues
Published in Zeitschrift fur medizinische Laboratoriumsdiagnostik (1986)Get more information
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Malondialdehyde determination in the liver, lung and brain of the rat
Published in Zeitschrift fur medizinische Laboratoriumsdiagnostik (1985)Get more information
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