Search Results - "Schaeffer, D.F."

Whole genome and transcriptome analysis enhances precision cancer treatment options by Pleasance, E., Bohm, A., Williamson, L.M., Nelson, J.M.T., Shen, Y., Bonakdar, M., Titmuss, E., Csizmok, V., Wee, K., Hosseinzadeh, S., Grisdale, C.J., Reisle, C., Taylor, G.A., Lewis, E., Jones, M.R., Bleile, D., Sadeghi, S., Zhang, W., Davies, A., Pellegrini, B., Wong, T., Bowlby, R., Chan, S.K., Mungall, K.L., Chuah, E., Mungall, A.J., Moore, R.A., Zhao, Y., Deol, B., Fisic, A., Fok, A., Regier, D.A., Weymann, D., Schaeffer, D.F., Young, S., Yip, S., Schrader, K., Levasseur, N., Taylor, S.K., Feng, X., Tinker, A., Savage, K.J., Chia, S., Gelmon, K., Sun, S., Lim, H., Renouf, D.J., Jones, S.J.M., Marra, M.A., Laskin, J.

“…Recent advances are enabling delivery of precision genomic medicine to cancer clinics. While the majority of approaches profile panels of selected genes or…”
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Successful targeting of the NRG1 pathway indicates novel treatment strategy for metastatic cancer by Jones, M.R., Lim, H., Shen, Y., Pleasance, E., Ch'ng, C., Reisle, C., Leelakumari, S., Zhao, C., Yip, S., Ho, J., Zhong, E., Ng, T., Ionescu, D., Schaeffer, D.F., Mungall, A.J., Mungall, K.L., Zhao, Y., Moore, R.A., Ma, Y., Chia, S., Ho, C., Renouf, D.J., Gelmon, K., Jones, S.J.M., Marra, M.A., Laskin, J.

“…NRG1 fusion-positive lung cancers have emerged as potentially actionable events in lung cancer, but clinical support is currently limited and no evidence of…”
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LBA65 The Canadian Cancer Trials Group PA.7 trial: Results of a randomized phase II study of gemcitabine (GEM) and nab-paclitaxel (Nab-P) vs GEM, nab-P, durvalumab (D) and tremelimumab (T) as first line therapy in metastatic pancreatic ductal adenocarcinoma (mPDAC) by Renouf, D.J., Knox, J.J., Kavan, P., Jonker, D., Welch, S., Couture, F., Lemay, F., Tehfe, M., Harb, M., Aucoin, N., Ko, Y-J., Tang, P., Ramjeesingh, R., Meyers, B.M., Kim, C., Schaeffer, D.F., Loree, J., Gill, S., Tu, D., O'Callaghan, C.

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Clinical utility of circulating tumor DNA (ctDNA) in resectable pancreatic ductal adenocarcinoma (PDAC) by Wong, H.-L., Bushell, K., Karasinska, J., Arthur, S., Pararajalingam, P., Morin, R., Schaeffer, D.F., Renouf, D.J.

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Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study by Sheffield, B S, Tessier-Cloutier, B, Li-Chang, H, Shen, Y, Pleasance, E, Kasaian, K, Li, Y, Jones, S J M, Lim, H J, Renouf, D J, Huntsman, D G, Yip, S, Laskin, J, Marra, M, Schaeffer, D F

“…Gastrointestinal carcinomas are genomically complex cancers that are lethal in the metastatic setting. Whole-genome and transcriptome sequencing allow for the…”
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Evidence for increased nitric oxide production in the auditory brain stem of the aged dwarf hamster ( Phodopus sungorus): an NADPH-diaphorase histochemical study by Reuss, S., Schaeffer, D.F., Laages, M.H., Riemann, R.

“…Age-related changes of the auditory system such as presbyacusis are believed to be due, at least in part, to alterations of central structures. The superior…”
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