Search Results - "Schaeffer, Alexandre"
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Acto-myosin network geometry defines centrosome position
Published in Current biology (22-03-2021)“…The centrosome is the main organizer of microtubules and as such, its position is a key determinant of polarized cell functions. As the name says, the default…”
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Force balance of opposing diffusive motors generates polarity-sorted microtubule patterns
Published in Proceedings of the National Academy of Sciences - PNAS (03-12-2024)“…The internal organization of cells is largely determined by the architecture and orientation of the microtubule network. Microtubules serve as polar tracks for…”
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Microtubules self-repair in living cells
Published in Current biology (09-01-2023)“…Microtubule self-repair has been studied both in vitro and in vivo as an underlying mechanism of microtubule stability. The turnover of tubulin dimers along…”
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Microtubules under mechanical pressure can breach dense actin networks
Published in Journal of cell science (15-11-2023)“…The crosstalk between the actin network and microtubules is essential for cell polarity. It orchestrates microtubule organization within the cell, driven by…”
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Hematopoietic progenitors polarize in contact with bone marrow stromal cells in response to SDF1
Published in The Journal of cell biology (01-11-2021)“…The fate of hematopoietic stem and progenitor cells (HSPCs) is regulated by their interaction with stromal cells in the bone marrow. However, the cellular…”
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