Search Results - "Schaefer, Dirk"

Cloud-based design and manufacturing: A new paradigm in digital manufacturing and design innovation by Wu, Dazhong, Rosen, David W., Wang, Lihui, Schaefer, Dirk

“…Cloud-based design manufacturing (CBDM) refers to a service-oriented networked product development model in which service consumers are enabled to configure,…”
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Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational first-in-human trial by Mumme, Marcus, MD, Barbero, Andrea, PhD, Miot, Sylvie, PhD, Wixmerten, Anke, MSc, Feliciano, Sandra, BSc, Wolf, Francine, BSc, Asnaghi, Adelaide M, PhD, Baumhoer, Daniel, Prof, Bieri, Oliver, PhD, Kretzschmar, Martin, MD, Pagenstert, Geert, MD, Haug, Martin, MD, Schaefer, Dirk J, Prof, Martin, Ivan, Prof, Jakob, Marcel, Prof

“…Summary Background Articular cartilage injuries have poor repair capacity, leading to progressive joint damage, and cannot be restored predictably by either…”
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Cloud manufacturing: Strategic vision and state-of-the-art by Wu, Dazhong, Greer, Matthew John, Rosen, David W., Schaefer, Dirk

“…•A strategic vision of the new paradigm of cloud-based manufacturing systems.•A review of the current implementation state in industry.•A road map for future…”
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It Takes Two to Tango: Coupling of Angiogenesis and Osteogenesis for Bone Regeneration by Grosso, Andrea, Burger, Maximilian G, Lunger, Alexander, Schaefer, Dirk J, Banfi, Andrea, Di Maggio, Nunzia

“…Bone regeneration is a complex process requiring highly orchestrated interactions between different cells and signals to form new mineralized tissue. Blood…”
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Engineered autologous cartilage tissue for nasal reconstruction after tumour resection: an observational first-in-human trial by Fulco, Ilario, MD, Miot, Sylvie, PhD, Haug, Martin D, Dr, Barbero, Andrea, PhD, Wixmerten, Anke, MSc, Feliciano, Sandra, BSc, Wolf, Francine, BSc, Jundt, Gernot, Prof, Marsano, Anna, PhD, Farhadi, Jian, MD, Heberer, Michael, Prof, Jakob, Marcel, Prof, Schaefer, Dirk J, Prof, Martin, Ivan, Prof

“…Summary Background Autologous native cartilage from the nasal septum, ear, or rib is the standard material for surgical reconstruction of the nasal alar lobule…”
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Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues by Stüdle, Chiara, Vallmajó-Martín, Queralt, Haumer, Alexander, Guerrero, Julien, Centola, Matteo, Mehrkens, Arne, Schaefer, Dirk J., Ehrbar, Martin, Barbero, Andrea, Martin, Ivan

“…Despite the various reported approaches to generate osteochondral composites by combination of different cell types and materials, engineering of templates…”
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Robust coupling of angiogenesis and osteogenesis by VEGF-decorated matrices for bone regeneration by Burger, Maximilian G., Grosso, Andrea, Briquez, Priscilla S., Born, Gordian M.E., Lunger, Alexander, Schrenk, Flavio, Todorov, Atanas, Sacchi, Veronica, Hubbell, Jeffrey A., Schaefer, Dirk J., Banfi, Andrea, Di Maggio, Nunzia

“…Rapid vascularization of clinical-size bone grafts is an unsolved challenge in regenerative medicine. Vascular endothelial growth factor-A (VEGF) is the master…”
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Fractionated human adipose tissue as a native biomaterial for the generation of a bone organ by endochondral ossification by Guerrero, Julien, Pigeot, Sebastien, Müller, Judith, Schaefer, Dirk J, Martin, Ivan, Scherberich, Arnaud

“…[Display omitted] Many steps are required to generate bone through endochondral ossification with adipose mesenchymal stromal cells (ASC), from cell isolation…”
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Lipidomics Profiling of Hidradenitis Suppurativa Skin Lesions Reveals Lipoxygenase Pathway Dysregulation and Accumulation of Proinflammatory Leukotriene B4 by Penno, Carlos A., Jäger, Petra, Laguerre, Claire, Hasler, Franziska, Hofmann, Andreas, Gass, Stephanie K., Wettstein-Ling, Barbara, Schaefer, Dirk J., Avrameas, Alexandre, Raulf, Friedrich, Wieczorek, Grazyna, Lehmann, Joachim C.U., Loesche, Christian, Roth, Lukas, Röhn, Till A.

“…Hidradenitis suppurativa (HS) is a chronic, recurring inflammatory dermatosis characterized by abscesses, deep-seated nodules, sinus tracts, and fibrosis in…”
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The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Preclinical Evidence by Oranges, Carlo M., Striebel, Julia, Tremp, Mathias, Madduri, Srinivas, Kalbermatten, Daniel F., Harder, Yves, Schaefer, Dirk J.

“…Several methods to prepare the recipient site in fat grafting have been proposed in recent decades. However, to date, these procedures have never been reviewed…”
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Validating Facial Aesthetic Surgery Results with the FACE-Q by Kappos, Elisabeth A., Temp, Mathias, Schaefer, Dirk J., Haug, Martin, Kalbermatten, Daniel F., Toth, Bryant A.

“…BACKGROUND:In aesthetic clinical practice, surgical outcome is best measured by patient satisfaction and quality of life. For many years, there has been a lack…”
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Engraftment of Prevascularized, Tissue Engineered Constructs in a Novel Rabbit Segmental Bone Defect Model by Kaempfen, Alexandre, Todorov, Atanas, Güven, Sinan, Largo, René D, Jaquiéry, Claude, Scherberich, Arnaud, Martin, Ivan, Schaefer, Dirk J

“…The gold standard treatment of large segmental bone defects is autologous bone transfer, which suffers from low availability and additional morbidity. Tissue…”
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Risk factors of major complications after flap surgery in the treatment of stage III and IV pressure injury in people with spinal cord injury/disorder: a retrospective cohort study by Fähndrich, Carina, Gemperli, Armin, Baumberger, Michael, Harder, Michael, Roth, Bianca, Schaefer, Dirk J., Wettstein, Reto, Scheel-Sailer, Anke

“…Study design Retrospective cohort study. Objectives To identify risk factors associated with major complications after flap surgery in people with spinal cord…”
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Harnessing human adipose-derived stromal cell chondrogenesis in vitro for enhanced endochondral ossification by Chaaban, Mansoor, Moya, Adrien, García-García, Andres, Paillaud, Robert, Schaller, Romain, Klein, Thibaut, Power, Laura, Buczak, Katarzyna, Schmidt, Alexander, Kappos, Elisabeth, Ismail, Tarek, Schaefer, Dirk J, Martin, Ivan, Scherberich, Arnaud

“…Endochondral ossification (ECO), the major ossification process during embryogenesis and bone repair, involves the formation of a cartilaginous template…”
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Implantation of Stromal Vascular Fraction Progenitors at Bone Fracture Sites: From a Rat Model to a First‐in‐Man Study by Saxer, Franziska, Scherberich, Arnaud, Todorov, Atanas, Studer, Patrick, Miot, Sylvie, Schreiner, Simone, Güven, Sinan, Tchang, Laurent A.H., Haug, Martin, Heberer, Michael, Schaefer, Dirk J., Rikli, Daniel, Martin, Ivan, Jakob, Marcel

“…Stromal Vascular Fraction (SVF) cells freshly isolated from adipose tissue include osteogenic‐ and vascular‐progenitors, yet their relevance in bone fracture…”
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Efficacy, safety and complications of autologous fat grafting to healthy breast tissue: A systematic review by Largo, Rene D, Tchang, Laurent A.H, Mele, Valentina, Scherberich, Arnaud, Harder, Yves, Wettstein, Reto, Schaefer, Dirk J

“…Summary Background Fat grafting for primary breast augmentation is growing in popularity due to its autologous properties and its side benefit of removing…”
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A composite, off-the-shelf osteoinductive material for large, vascularized bone flap prefabrication by Kouba, Loraine, Bürgin, Joël, Born, Gordian, Perale, Giuseppe, Schaefer, Dirk J., Scherberich, Arnaud, Pigeot, Sébastien, Martin, Ivan

“…We previously described an immortalized, genetically-engineered human Mesenchymal stromal cell line to generate BMP2-enriched Chondrogenic Matrices (MB-CM),…”
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Increasing Fat Graft Retention in Irradiated Tissue after Preconditioning with External Volume Expansion by Oranges, Carlo M., Madduri, Srinivas, Kalbermatten, Daniel F., Schaefer, Dirk J.

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Engineering of large osteogenic grafts with rapid engraftment capacity using mesenchymal and endothelial progenitors from human adipose tissue by Güven, Sinan, Mehrkens, Arne, Saxer, Franziska, Schaefer, Dirk J, Martinetti, Roberta, Martin, Ivan, Scherberich, Arnaud

“…Abstract We investigated whether the maintenance in culture of endothelial and mesenchymal progenitors from the stromal vascular fraction (SVF) of human…”
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Therapeutic vascularization in regenerative medicine by Gianni‐Barrera, Roberto, Di Maggio, Nunzia, Melly, Ludovic, Burger, Maximilian G., Mujagic, Edin, Gürke, Lorenz, Schaefer, Dirk J., Banfi, Andrea

“…Therapeutic angiogenesis, that is, the generation of new vessels by delivery of specific factors, is required both for rapid vascularization of…”
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