Search Results - "Schaefer, Caralee"

Gait analysis in a murine model of collagen-induced arthritis by Vincelette, Jon, Xu, Yifan, Zhang, Le-Ning, Schaefer, Caralee J, Vergona, Ronald, Sullivan, Mark E, Hampton, Thomas G, Wang, Yi-Xin Jim

“…Murine collagen-induced arthritis (CIA) has become a valuable animal model for elucidating pathogenic mechanisms and evaluating therapeutic effects for…”
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Danoprevir Monotherapy Decreases Inflammatory Markers in Patients with Chronic Hepatitis C Virus Infection by SCHAEFER, Caralee J, KOSSEN, Karl, LIM, Sharlene R, LIN, Jiing-Huey, LIN PAN, BRADFORD, Williamson, SMITH, Patrick F, SEIWERT, Scott D

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immune reactions associated with silicone-based ventriculo-peritoneal shunt malfunctions in children by VandeVord, Pamela J., Gupta, Nalini, Wilson, Russell B., Vinuya, Ricardo Z., Schaefer, Caralee J., Canady, Alexa I., Wooley, Paul H.

“…The implantation of ventriculo-peritoneal (VP) shunting systems is the most commonly performed neurological procedure in children with hydrocephalus. Although…”
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Influence of long term silicone implantation on type II collagen induced arthritis in mice by Schaefer, Caralee J, Lawrence, W Dwayne, Wooley, Paul H

“…OBJECTIVES The use of silicone implants in cosmetic and reconstructive surgery has been implicated in the development of autoimmune connective tissue diseases…”
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IDL-2965: a selective, highly potent, clinical-stage integrin antagonist for treatment of non-alcoholic steatohepatitis by Kossen, Karl, Schaefer, Caralee, Lim, Sharlene, Michener, Marshall, Griggs, Dave, Ruminski, Peter, Radhakrishnan, Ramachandran, Rubino, Christopher, Marmon, Tonya, Gershman, Ari, Hanning, Roxann, Jones, Renee, Kamau-Kelley, Watiri, Seiwert, Scott

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FRI103 - IDL-2965: a selective, highly potent, clinical-stage integrin antagonist for treatment of non-alcoholic steatohepatitis by Kossen, Karl, Schaefer, Caralee, Lim, Sharlene, Michener, Marshall, Griggs, Dave, Ruminski, Peter, Radhakrishnan, Ramachandran, Rubino, Christopher, Marmon, Tonya, Gershman, Ari, Hanning, Roxann, Jones, Renee, Kamau-Kelley, Watiri, Seiwert, Scott

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Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: Potential proinflammatory mechanisms by Thiel, Melissa J., Schaefer, Caralee J., Lesch, Mark E., Mobley, James L., Dudley, David T., Tecle, Haile, Barrett, Stephen D., Schrier, Denis J., Flory, Craig M.

“…Objective To evaluate the role of the MEK/ERK MAP kinase pathway in murine collagen‐induced arthritis (CIA) using the selective MEK inhibitor PD184352. We…”
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Preclinical Characterization and Human Microdose Pharmacokinetics of ITMN-8187, a Nonmacrocyclic Inhibitor of the Hepatitis C Virus NS3 Protease by Rajagopalan, Ravi, Pan, Lin, Schaefer, Caralee, Nicholas, John, Lim, Sharlene, Misialek, Shawn, Stevens, Sarah, Hooi, Lisa, Aleskovski, Natalia, Ruhrmund, Donald, Kossen, Karl, Huang, Lea, Yap, Sophia, Beigelman, Leonid, Serebryany, Vladimir, Liu, Jyanwei, Sastry, Srikonda, Seiwert, Scott, Buckman, Brad

“…The current paradigm for the treatment of chronic hepatitis C virus (HCV) infection involves combinations of agents that act directly on steps of the HCV life…”
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Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis by Islam, Imadul, Yuan, Shendong, West, Christopher W., Adler, Marc, Bothe, Ulrich, Bryant, Judi, Chang, Zheng, Chu, Kieu, Emayan, Kumar, Gualtieri, Giovanna, Ho, Elena, Light, David, Mallari, Cornell, Morser, John, Phillips, Gary, Schaefer, Caralee, Sukovich, Drew, Whitlow, Marc, Chen, Deborah, Buckman, Brad O.

“…[Display omitted] •Design and synthesis of benzylamine based selective and orally available inhibitors of uPA has been described.•Prior knowledge of SAR has…”
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Effects of the phosphodiesterase inhibitor rolipram on streptococcal cell wall-induced arthritis in rats by Laemont, Keith D, Schaefer, Caralee J, Juneau, Paul L, Schrier, Denis J

“…The phosphodiesterase-IV (PDE-IV) inhibitor, rolipram, is antiinflammatory in a number of animal models and inhibits the release of a variety of cytokines,…”
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Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo by Guilford, William J, Bauman, John G, Skuballa, Werner, Bauer, Shawn, Wei, Guo Ping, Davey, David, Schaefer, Caralee, Mallari, Cornell, Terkelsen, Jennifer, Tseng, Jih-Lie, Shen, Jun, Subramanyam, Babu, Schottelius, Arndt J, Parkinson, John F

“…Lipoxin A4 (LXA4) is a structurally and functionally distinct natural product called an eicosanoid, which displays immunomodulatory and anti-inflammatory…”
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New Roles for LTA4 Hydrolase, LTB4 and BLT1 in Multiple Sclerosis and Experimental Allergic Encephalomyelitis (48.9) by Parkinson, John F, Guilford, William J, Mendoza, Lisa M, Rosser, Mary, Post, Joseph, Schaefer, Caralee, Halks-Miller, Meredith, Kirkland, Tom, Cleve, Arwed, Lassmann, Hans, Reder, Anthony T

“…Abstract 5-lipoxygenase (5-LO), leukotriene A4 hydrolase (LTA4h), leukotriene B4 (LTB4) and its high affinity receptor BLT1 are known drivers of allergy,…”
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Expression of Leukotrienes is Increased in Human MS and in a Mouse Adoptive Transfer Model of MS (B98) by Mendoza, Lisa M., King, Beverly, Rosser, Mary, Almond, Cosima, Hidalgo, ToniRose, Schaefer, Caralee, Mahmoudi, Mithra, Harvey, Susan, Kirkland, Thomas, Guilford, William, Vogel, David, Lassmann, Hans, Reder, Anthony, Parkinson, John, Halks-Miller, Meridith

“…Abstract Leukotrienes are well established as mediators of inflammation, however little is known regarding their role in the pathogenesis of multiple sclerosis…”
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Mx1 and IP-10: biomarkers to measure IFN-beta activity in mice following gene-based delivery by Petry, Harald, Cashion, Linda, Szymanski, Paul, Ast, Oliver, Orme, Ann, Gross, Cynthia, Bauzon, Maxine, Brooks, Alan, Schaefer, Caralee, Gibson, Heather, Qian, Husheng, Rubanyi, Gabor M, Harkins, Richard N

“…Recombinant interferon-beta (IFN-beta) protein is used successfully for the treatment of multiple sclerosis (MS). Gene therapy might be an alternative approach…”
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Gene-based delivery of IFN-beta is efficacious in a murine model of experimental allergic encephalomyelitis by Schaefer, Caralee, Hidalgo, Toni Rose, Cashion, Linda, Petry, Harald, Brooks, Alan, Szymanski, Paul, Qian, Hu Sheng, Gross, Cynthia, Wang, Peiyin, Liu, Perry, Goldman, Claudia, Rubanyi, Gabor M, Harkins, Richard N

“…Experimental allergic encephalomyelitis (EAE) is a model of central nervous system (CNS) inflammation that follows immunization with certain CNS antigens. The…”
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The influence of silicone implantation on murine lupus in MRL lpr/lpr mice by Schaefer, C J, Wooley, P H

“…The use of silicone breast implants has been implicated in the development of autoimmune connective tissue diseases including systemic lupus erythematosus…”
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Novel 3-Oxa Lipoxin A 4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo by Guilford, William J., Bauman, John G., Skuballa, Werner, Bauer, Shawn, Wei, Guo Ping, Davey, David, Schaefer, Caralee, Mallari, Cornell, Terkelsen, Jennifer, Tseng, Jih-Lie, Shen, Jun, Subramanyam, Babu, Schottelius, Arndt J., Parkinson, John F.

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A peptide sequence from platelet factor 4 (CT-112) is effective in the treatment of type II collagen induced arthritis in mice by Wooley, P H, Schaefer, C, Whalen, J D, Dutcher, J A, Counts, D F

“…Platelet factor 4 (PF-4) is a critical alpha chemokine in inflammation and injury responses, with multiple effects upon cellular activities. Discrete peptide…”
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The influence of silicone implantation on experimental models of autoimmunity by Schaefer, Caralee Joyce

“…The use of silicone implants in cosmetic and reconstructive surgery has recently been implicated in the development of autoimmune connective tissue diseases…”
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Differential inhibition of inducible T cell cytokine secretion by potent iron chelators by Leung, Stewart, Holbrook, April, King, Beverly, Lu, Hong-Tao, Evans, Vincent, Miyamoto, Neil, Mallari, Cornell, Harvey, Susan, Davey, Dave, Ho, Elena, Li, Wei-Wei, Parkinson, John, Horuk, Richard, Jaroch, Stefan, Berger, Markus, Skuballa, Werner, West, Christopher, Pulk, Rebecca, Phillips, Gary, Bryant, Judi, Subramanyam, Babu, Schaefer, Caralee, Salamon, Hugh, Lyons, Eric, Schilling, Daniela, Seidel, Henrik, Kraetzschmar, Joern, Snider, Michael, Perez, Daniel

“…Effector functions and proliferation of T helper (Th) cells are influenced by cytokines in the environment. Th1 cells respond to a synergistic effect of…”
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