Search Results - "Schachter, J"

Pembrolizumab for locally advanced and recurrent/metastatic cutaneous squamous cell carcinoma (KEYNOTE-629 study): an open-label, nonrandomized, multicenter, phase II trial by Hughes, B.G.M., Munoz-Couselo, E., Mortier, L., Bratland, Å., Gutzmer, R., Roshdy, O., González Mendoza, R., Schachter, J., Arance, A., Grange, F., Meyer, N., Joshi, A., Billan, S., Zhang, P., Gumuscu, B., Swaby, R.F., Grob, J.-J.

“…Pembrolizumab demonstrated clinically meaningful and durable antitumor activity with a manageable safety profile in recurrent/metastatic (R/M) cutaneous…”
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Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study by McArthur, G.A., Maio, M., Arance, A., Nathan, P., Blank, C., Avril, M.-F., Garbe, C., Hauschild, A., Schadendorf, D., Hamid, O., Fluck, M., Thebeau, M., Schachter, J., Kefford, R., Chamberlain, M., Makrutzki, M., Robson, S., Gonzalez, R., Margolin, K.

“…Vemurafenib has shown activity in patients withBRAFV600 mutated melanoma with brain metastases (BM). This phase 2 study evaluated vemurafenib in patients…”
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Simultaneous Optogenetics and Cellular Resolution Calcium Imaging During Active Behavior Using a Miniaturized Microscope by Stamatakis, Alice M, Schachter, Mike J, Gulati, Srishti, Zitelli, Kevin T, Malanowski, Sam, Tajik, Arash, Fritz, Christopher, Trulson, Mark, Otte, Stephani L

“…The ability to precisely monitor and manipulate neural circuits is essential to understand the brain. Advancements over the last decade in optical techniques…”
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A critical review of Real Options thinking for valuing investment flexibility in Smart Grids and low carbon energy systems by Schachter, J.A., Mancarella, P.

“…This paper aims at serving as a critical analysis of Real Options (RO) methodologies that have so far been applied to the flexible evaluation of smart grid…”
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Dendritic spikes amplify the synaptic signal to enhance detection of motion in a simulation of the direction-selective ganglion cell by Schachter, Michael J, Oesch, Nicholas, Smith, Robert G, Taylor, W Rowland

“…The On-Off direction-selective ganglion cell (DSGC) in mammalian retinas responds most strongly to a stimulus moving in a specific direction. The DSGC…”
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Pharmacogenetic neuronal stimulation increases human tau pathology and trans-synaptic spread of tau to distal brain regions in mice by Schultz, M.K., Gentzel, R., Usenovic, M., Gretzula, C., Ware, C., Parmentier-Batteur, S., Schachter, J.B., Zariwala, H.A.

“…In Alzheimer's Disease (AD), tau pathology has a spatiotemporally distinct pattern of progressive spread along anatomically connected neural pathways…”
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Corrigendum to ‘Pembrolizumab for locally advanced and recurrent/metastatic cutaneous squamous cell carcinoma (KEYNOTE-629 study): an open-label, nonrandomized, multicenter, phase II trial: [Annals of Oncology Volume 32, Issue 10, October 2021, Pages 1276-1285] by Hughes, B.G.M., Munoz-Couselo, E., Mortier, L., Bratland, Å., Gutzmer, R., Roshdy, O., González Mendoza, R., Schachter, J., Arance, A., Grange, F., Meyer, N., Joshi, A., Billan, S., Zhang, P., Gumuscu, B., Swaby, R.F., Grob, J.-J.

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Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006 by Long, G.V., Arance, A., Mortier, L., Lorigan, P., Blank, C., Mohr, P., Schachter, J., Grob, J.-J., Lotem, M., Middleton, M.R., Neyns, B., Steven, N., Ribas, A., Walpole, E., Carlino, M.S., Lebbe, C., Sznol, M., Jensen, E., Leiby, M.A., Ibrahim, N., Robert, C.

“…Antitumor activity of ipilimumab or BRAF ± MEK inhibitors (BRAFi ± MEKi) following pembrolizumab administration in melanoma is poorly characterized. In the…”
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The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases: A multicenter cohort study by Olofsson Bagge, Roger, Holmberg, Carl Jacob, Hieken, Tina J., Zager, Jonathan S., Long, Georgina V., Van Akkooi, Alexander Christopher Jonathan, Karakousis, Giorgos C, Pallan, Lalit, Vetto, John T., Gyorki, David E., Ascierto, Paolo Antonio, Dummer, Reinhard, Hui, Jane Yuet Ching, Schachter, Jacob, Helgadottir, Hildur, Kroon, Hidde, Rothermel, Luke Daniel, Carlino, Matteo S., Broman, Kristy Kummerow, Ny, Lars

“…9569 Background: Guidelines addressing melanoma in-transit metastasis (ITM) recommend immune checkpoint inhibitors (ICI) as a first-line treatment option,…”
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KEYNOTE-022 Part 3: Phase II randomized study of 1L dabrafenib (D) and trametinib (T) plus pembrolizumab (Pembro) or placebo (PBO) for BRAF-mutant advanced melanoma by Ascierto, P.A., Ferrucci, P.F., Stephens, R., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G.V., Di Giacomo, A.M., Svane, I., Lotem, M., Bar-Sela, G., Couture, F., Mookerjee, B.P., Ghori, R., Ibrahim, N., Homet Moreno, B., Ribas, A.

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In vivo Calcium Imaging Reveals That Cortisol Treatment Reduces the Number of Place Cells in Thy1-GCaMP6f Transgenic Mice by Indersmitten, Tim, Schachter, Michael J, Young, Stephanie, Welty, Natalie, Otte, Stephani, Nassi, Jonathan J, Lovenberg, Timothy, Bonaventure, Pascal, Wyatt, Ryan M

“…The hippocampus, a structure essential for spatial navigation and memory undergoes anatomical and functional changes during chronic stress. Here, we…”
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IN VITRO ANALYSIS PREDICTS CLINICAL RESPONSE OF B CELL LYMPHATIC MALIGNANCIES TO CD19 CAR‐T CELLS: PHENOTYPIC, TRANSCRIPTIONAL AND FUNCTIONAL STUDY by Beider, K., Besser, M. J., Jacoby, E., Schachter, J., Voevoda‐Dimenshtein, V., Rosenberg, E., Ostrovsky, O., Danylesko, I., Shimoni, A., Avigdor, A., Nagler, A.

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Performance of the APTIMA Combo 2 Assay for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Female Urine and Endocervical Swab Specimens by GAYDOS, C. A, QUINN, T. C, WILLIS, D, WEISSFELD, A, HOOK, E. W, MARTIN, D. H, FERRERO, D. V, SCHACHTER, J

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immunotherapy of distant metastatic disease by Schadendorf, D., Algarra, S. M., Bastholt, L., Cinat, G., Dreno, B., Eggermont, A. M. M., Espinosa, E., Guo, J., Hauschild, A., Petrella, T., Schachter, J., Hersey, P.

“…Immunotherapy of metastatic melanoma consists of various approaches leading to specific or non-specific immunomodulation. The use of FDA-approved interleukin…”
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Paclitaxel Versus Doxorubicin as First-Line Single-Agent Chemotherapy for Metastatic Breast Cancer: A European Organization for Research and Treatment of Cancer Randomized Study With Cross-Over by PARIDAENS, R, BIGANZOLI, L, AWADA, A, WILDIERS, J, PICCART, M, BRUNING, P, KLIJN, J. G. M, GAMUCCI, T, HOUSTON, S, COLEMAN, R, SCHACHTER, J, VAN VRECKEM, A, SYLVESTER, R

“…To compare the efficacy of paclitaxel versus doxorubicin given as single agents in first-line therapy of advanced breast cancer (primary end point,…”
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Estimate of long-term relapse-free survival (RFS) and analysis of baseline factors associated with RFS in the COMBI-AD trial by Dummer, R., Schadendorf, D., Hauschild, A., Santinami, M., Atkinson, V.G., Mandala, M., Chiarion Sileni, V., Larkin, J., Nyakas, M.S., Dutriaux, C., Haydon, A., Mortier, L., Robert, C., Schachter, J., Feng, X., de Jong, E., Mookerjee, B., Kefford, R., Kirkwood, J.M., Long, G.V.

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Adverse events (AEs) over time in patients (pts) treated with adjuvant dabrafenib plus trametinib (D + T) or placebo (Pbo) in the COMBI-AD trial by Atkinson, V.G., Hauschild, A., Santinami, M., Mandala, M., Chiarion Sileni, V., Larkin, J., Nyakas, M.S., Dutriaux, C., Haydon, A., Mortier, L., Robert, C., Schachter, J., Schadendorf, D., Feng, X., de Jong, E., Mookerjee, B., Kefford, R., Dummer, R., Kirkwood, J.M., Long, G.V.

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Efficacy of pembrolizumab in patients with advanced mucosal melanoma enrolled in the KEYNOTE-001, 002, and 006 studies by Butler, M, Hamid, O, Ribas, A, Hodi, F.S, Walpole, E, Dauad, A, Arance, A, Brown, E, Hoeller, C, Mortier, L, Schachter, J, Long, J, Ebbinghaus, S, Ibrahim, N, Robert, C

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Antitumor activity of ipilimumab after pembrolizumab in patients with advanced melanoma in KEYNOTE-006 by Long, G.V, Robert, C, Arance, A, Blank, C, Ribas, A, Lorigan, P, Mortier, L, Schachter, J, Middleton, M.R, Neyns, B, Sznol, M, Zhou, H, Ebbinghaus, S, Ibrahim, N, Steven, N

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CEACAM1 in malignant melanoma: a diagnostic and therapeutic target by Sapoznik, S, Ortenberg, R, Schachter, J, Markel, G

“…CEACAM1 adhesion molecule is broadly expressed, participates in pivotal cellular and immunological processes and is involved in cancer. Originally identified…”
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