Search Results - "Schabla, N Max"

VprBP (DCAF1) Regulates RAG1 Expression Independently of Dicer by Mediating RAG1 Degradation by Schabla, N Max, Perry, Greg A, Palmer, Victoria L, Swanson, Patrick C

“…The assembly of Ig genes in developing B lymphocytes by V(D)J recombination is initiated by the RAG1-RAG2 endonuclease complex. We previously identified an…”
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The CRL4VPRBP(DCAF1) E3 ubiquitin ligase directs constitutive RAG1 degradation in a non-lymphoid cell line by Schabla, N. Max, Swanson, Patrick C.

“…The development of B and T lymphocytes critically depends on RAG1/2 endonuclease activity to mediate antigen receptor gene assembly by V(D)J recombination…”
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Receptor editing constrains development of phosphatidyl choline-specific B cells in VH12-transgenic mice by Worth, Alexandra N., Palmer, Victoria L., Schabla, N. Max, Perry, Greg A., Fraser-Philbin, Anna N., Swanson, Patrick C.

“…B1 B cells reactive to phosphatidyl choline (PtC) exhibit restricted immunoglobulin heavy chain (HC) and light chain (LC) combinations, exemplified by…”
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DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor by Schabla, N Max, Mondal, Koushik, Swanson, Patrick C

“…Abstract Cullin-RING ligases (CRLs) comprise a large group of modular eukaryotic E3 ubiquitin ligases. Within this family, the CRL4 ligase (consisting of the…”
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The CRL4.sup.VPRBP by Schabla, N. Max, Swanson, Patrick C

“…The development of B and T lymphocytes critically depends on RAG1/2 endonuclease activity to mediate antigen receptor gene assembly by V(D)J recombination…”
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The CRL4.sup.VPRBP E3 ubiquitin ligase directs constitutive RAG1 degradation in a non-lymphoid cell line by Schabla, N. Max, Swanson, Patrick C

“…The development of B and T lymphocytes critically depends on RAG1/2 endonuclease activity to mediate antigen receptor gene assembly by V(D)J recombination…”
Get full text

VprBP/DCAF1 Regulates RAG1 Expression Independently of Dicer by Mediating RAG1 Degradation by Schabla, N. Max, Perry, Greg A., Palmer, Victoria L., Swanson, Patrick C.

“…The assembly of immunoglobulin genes in developing B lymphocytes by V(D)J recombination is initiated by the RAG1-RAG2 endonuclease complex. We previously…”
Get full text

Receptor editing constrains development of phosphatidyl choline-specific B cells in V H 12-transgenic mice by Worth, Alexandra N, Palmer, Victoria L, Schabla, N Max, Perry, Greg A, Fraser-Philbin, Anna N, Swanson, Patrick C

“…B1 B cells reactive to phosphatidyl choline (PtC) exhibit restricted immunoglobulin heavy chain (HC) and light chain (LC) combinations, exemplified by V…”
Get full text