Search Results - "Schaap, Nicolaas PM"

TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer by Maas, Ralph Ja, Hoogstad-van Evert, Janneke S, Van der Meer, Jolien Mr, Mekers, Vera, Rezaeifard, Somayeh, Korman, Alan J, de Jonge, Paul Kjd, Cany, Jeannette, Woestenenk, Rob, Schaap, Nicolaas Pm, Massuger, Leon F, Jansen, Joop H, Hobo, Willemijn, Dolstra, Harry

“…Advanced ovarian cancer (OC) patients have a poor 5-year survival of only 28%, emphasizing the medical need for improved therapies. Adjuvant immunotherapy…”
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Additional cytogenetic features determine outcome in patients allografted for TP53 mutant acute myeloid leukemia by Loke, Justin, Labopin, Myriam, Craddock, Charles, Cornelissen, Jan J., Labussière‐Wallet, Hélène, Wagner‐Drouet, Eva Maria, Van Gorkom, Gwendolyn, Schaap, Nicolaas P.M., Kröger, Nicolaus M., Veelken, Joan Hendrik, Rovira, Montserrat, Menard, Anne Lise, Bug, Gesine, Bazarbachi, Ali, Giebel, Sebastian, Brissot, Eolia, Nagler, Arnon, Esteve, Jordi, Mohty, Mohamad

“…BACKGROUND The presence of TP53 mutations is associated with an unfavorable outcome in patients allografted for acute myeloid leukemia (AML), leading some to…”
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A Comparison of Fractionated Myeloablative Total Body Irradiation Schedules Combined with Chemotherapy As Conditioning for Allograft Bone Marrow Transplantation in Patients with Acute Leukemia: The Sarasin Study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT) by Belkacemi, Yazid, Labopin, Myriam, Giebel, Sebastian, Loganadane, Gokoulakrichenane, Miszyk, Leszek, Beohou, Eric, Michallet, Mauricette, Socie, Gerard, Schaap, Nicolaas PM, Cornelissen, Jan J., Yakoub-Agha, Ibrahim, Mohty, Mohamad, Nagler, Arnon

“…Introduction Total-body irradiation (TBI) has an historical established role in preparative regimens used before allogeneic transplant in both acute…”
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Salvage Use of Ibrutinib after Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) for B Cell Malignancies: A Study of the French Cooperative Group for CLL, the French Soceity for Blood and Marrow Transplantation (SFGM-TC), and the European Society for Blood and Marrow Transplantation (EBMT) Chronic Malignancy and Lymphoma Working Parties by Michallet, Mauricette, Dreger, Peter, Sobh, Mohamad, Hoek, Jennifer, Boumendil, Ariane, Muller, Lutz, Corradini, Paolo, Bethge, Wolfgang, Russo, Domenico, Durakovic, Nadira, van Gelder, Michel, Schaap, Nicolaas PM, Kroger, Nicolaus, Schetelig, Johannes

“…BACKGROUND: Allo-HSCT is an accepted treatment option for patients with relapsed and refractory B cell lymphomas or high-risk chronic lymphocytic leukemia…”
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Non Interventional Prospective Clinical Study on Peripheral Blood Stem Cell Mobilization in Patients with Relapsed Lymphomas by van Gorkom, Gwendolyn, Finel, Herve, Giebel, Sebastian, Pohlreich, David, Shimoni, Avichai, Ringhoffer, Mark, Sucak, Gulsan Ayhan, Schaap, Nicolaas PM, Dreger, Peter, Sureda, Anna, Schouten, Harry C

“…Introduction: Autologous stem cell transplantation (ASCT) is the standard of care for many patients with relapsed chemosensitive lymphoma. Peripheral blood…”
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The Aryl Hydrocarbon Receptor Antagonist Stemregenin 1 Stimulates Expression of NK Cell Related Transcription Factors, Thereby It Facilitates Generation of Highly Functional NK Cells in Vitro by Roeven, Mieke WH, Cany, Jeanette, Maas, Frans, Kohela, Arwa, Joop, Jansen, Blijlevens, Nicole MA, Schaap, Nicolaas PM, Dolstra, Harry

“…Introduction Allogeneic stem cell transplantation (SCT) can be a curative treatment for hematological malignancies. The therapeutic effectiveness is attributed…”
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Allogeneic Stem Cell Transplantation in Adult Patients with Acute Myeloid Leukemia and 17p Abnormalities in First Complete Remission: A Study from the Acute Leukemia Working Party (ALWP) of the European Society of Blood and Marrow Transplantation (EBMT) by Poiré, Xavier, Labopin, Myriam, Maertens, Johan, Yakoub-Agha, Ibrahim, Blaise, Didier, Ifrah, Norbert, Socie, Gerard, Gedde-Dhal, Tobias, Schaap, Nicolaas PM, Cornelissen, Jan, Milpied, Noel, Sanz, Jaime, Michaux, Lucienne, Esteve, Jordi, Mohty, Mohamad, Nagler, Arnon

“…Introduction: Acute myeloid leukemia (AML) with 17p abnormalities (abn(17p)), usually affecting TP53 locus, carries a very poor prognosis due to high…”
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Ibrutinib for Bridging to Allogeneic Hematopoietic Stem Cell Transplantation (alloHCT) in Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL) Is Safe and Effective: First Results of a Survey By the Chronic Malignancy and the Lymphoma Working Parties of the EBMT by Dreger, Peter, Michallet, Mauricette, Hoek, Jennifer, Boumendil, Ariane, Sobh, Mohamad, Muller, Lutz, Vandenberghe, Elisabeth A., Scortechini, Ilaria, Andersen, Niels S., Finke, Jurgen, Russo, Domenico, Passweg, Jakob R, Schoemans, Helene, Durakovic, Nadira, Labussiere, Helene, Berg, Tobias, Niederwieser, Dietger, Bethge, Wolfgang, Mordini, Nicola, van Gelder, Michel, Schaap, Nicolaas PM, Kroger, Nicolaus, Montoto, Silvia, Schetelig, Johannes

“…BACKGROUND: The advent of the Bruton's tyrosine kinase inhibitor ibrutinib has improved the outlook of patients with CLL and MCL failing chemoimmunotherapy…”
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Comparison of Haematopoietic Stem Cell Transplantation Approaches in Primary Plasma Cell Leukaemia by Lawless, Sarah, Simona, Iacobelli, van Biezen, Anja, Koster, Linda, Chevallier, Patrice, Blaise, Didier, Foà, Roberto, Tabrizi, Reza, Schaap, Nicolaas PM, Lenhoff, Stig, Russell, Nigel H., Poiré, Xavier, Petersen, Eefke, Cornelissen, Jan J., Di Bartolomeo, Paolo, Wilson, Keith, Schipperus, Martin, Lioure, Bruno, Arcese, William, Mufti, Ghulam J, Snowden, John A, Finke, Jurgen, Morris, Curly, Garderet, Laurent, Kröger, Nicolaus, Schönland, Stefan

“…Introduction Primary plasma cellleukemiais a rare and aggressive disorder. While autologous stem cell transplantation has been shown to improve outcome,…”
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Family Mismatched Donor Transplantation for Myelofibrosis: A Retrospective Analysis of the EBMT Chronic Leukaemia Working Party by Raj, Kavita, Olavarria, Eduardo, Eikema, Diderik-Jan, de Wreede, Liesbeth C, Koster, Linda, van Lint, Maria Teresa, Ciceri, Fabio, Passweg, Jakob, Schaap, Nicolaas PM, Carlson, Kristina, Blaise, Didier, Santarone, Stella, Vitek, Antonin, Diez-Martin, Jose L., McLornan, Donal, Robin, Marie, Chalandon, Yves, Kroeger, Nicolaus

“…Background: Allogeneic stem cell transplantation is a treatment option for patients with advanced myelofibrosis. Problems encountered include an increased risk…”
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The Impact of Allogeneic Stem Cell Transplantation As Part of First Line Treatment on Outcome of Patients with Multiple Myeloma Depends on the Method of Analysis by Devillier, Raynier, Versluis, Jurjen, Van der Holt, Bronno, Kersten, Marie Jose, Raymakers, Reinier, Zweegman, Sonja, Bos, Gerard M.J., Schaap, Nicolaas PM, Broyl, Annemiek, Sonneveld, Pieter, Lokhorst, Henk, Cornelissen, Jan J.

“…The value of allogeneic hematopoietic stem cell transplantation (alloHSCT) in the treatment of multiple myeloma (MM) patients continues to be debated…”
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Ex Vivo Generation Of Functional Plasmacytoid and Myeloid Dendritic Cells Is Strongly Promoted By The Aryl Hydrocarbon Receptor Antagonist Stemregenin 1 by Thordardottir, Soley, Basav N., Hangalapura, Hutten, Tim, Cossu, Marta, Spanholtz, Jan, Schaap, Nicolaas PM, Radstake, Timothy, Voort, Robbert van der, Dolstra, Harry

“…The prominent role of dendritic cells (DCs) in T cell activation is the rational for DC-based immunotherapy of cancer and infectious diseases. In cancer, DC…”
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Influence Of DNA Methyltransferese Inhibitors On The Anti-Leukemic Effect Of Umbilical Cord Blood Derived NK Cells Against Acute Myeloid Leukemia by Dolstra, Harry, Cany, Jeannette, van der Waart, Anniek B., Tordoir, Marleen, Hangalapura, Basav Nagaraj, Spanholtz, Jan, van der Voort, Robbert, Schaap, Nicolaas PM

“…Natural killer (NK) cell-based immunotherapy is a promising adjuvant, relatively non-toxic therapy approach for AML. However, further improvement of NK…”
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Akt Signalling Inhibition Promotes The Ex Vivo generation Of Minor Histocompatibility Antigen-Specific CD8+ Memory Stem T Cells by van der Waart, Anniek B., van der Weem, Noortje, Gattinoni, Luca, Schaap, Nicolaas PM, Voort, Robbert van der, Hobo, Willemijn, Dolstra, Harry

“…Allogeneic hematopoietic stem cell transplantation (allo-SCT) followed by donor lymphocyte infusion (DLI) is a potential curative treatment for patients…”
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Center Characteristics and Procedure-Related Factors Have an Impact on Outcomes of Allogeneic Transplantation for Patients with CLL: A Retrospective Analysis from the European Society for Blood and Marrow Transplantation (EBMT) by Schetelig, Johannes, de Wreede, Liesbeth C, Andersen, Niels S., Moreno, Carol, van Gelder, Michel, Vitek, Antonin, Karas, Michal, Michallet, Mauricette, Machaczka, Maciej J, Gramatzki, Martin, Beelen, Dietrich W., Finke, Jurgen, Delgado, Julio, Volin, Liisa, Passweg, Jakob, Dreger, Peter, Schaap, Nicolaas PM, Theobald, Matthias, Henseler, Anja, van Biezen, Anja, Bornhaeuser, Martin, Iacobella, Simona, Putter, Hein, Schönland, Stefen, Kröger, Nicolaus

“…Introduction:Even in the era of novel targeted therapies for the treatment of Chronic Lymphocytic Leukemia (CLL) patients, such as BTK, PI3K and BCL2…”
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Identification of Baseline Characteristics That Predict Good Outcome of Allogeneic Hematopoietic Cell Transplantation in Young Chronic Lymphocytic Leukemia Patients - a Retrospective Analysis from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation by van Gelder, Michel, Ziagkos, Dimitris, de Wreede, Liesbeth C, van Biezen, Anja, Dreger, Peter, Gramatzki, Martin, Stelljes, Matthias, Smedegaard Andersen, Niels, Schaap, Nicolaas PM, Vitek, Antonin, Beelen, Dietrich, Volin, Liisa, Finke, Jürgen, Passweg, Jakob R, Ganser, Arnold, Machaczka, Maciej J, Delgado, Julio, Krüger, William, Faber, Edgar, Socie, Gerard, Jindra, Pavel, Afanasyev, Boris V, Theobald, Matthias, Chalandon, Yves, Henseler, Anja, Schoenland, Stefan O., Nicolaus, Kroger, Schetelig, Johannes

“…Patients with relapsed/refractory chronic lymphocytic leukemia (CLL) have excellent responses with kinase or BCL2 inhibitors, but patients with high risk…”
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Donor Cell Derived Leukemia: Description Of 38 Cases and a Case Control Study by Engel, Nicole, Duarte, Rafael F., Labopin, Myriam, Schroeder, Thomas, Tischer, Johanna, Ljungman, Per T., Schaap, Nicolaas PM, Guyotat, Denis, Beguin, Yves, Nagler, Arnon, Schroyens, Wilfried A., Basak, Grzegorz Wladyslaw, Kolb, Hans Jochem, Badoglio, Manuela, Tichelli, Andre, Rovo, Alicia

“…▪ The development of leukemia in donor cells (DCL) in the recipient after an allogeneic hematopoietic transplantation is a rare but severe complication and has…”
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The Revised IPSS (IPSS-R) At Transplant Predicts Overall and Relapse-Free Survival After Allogeneic Stem Cell Transplantation In MDS/sAML: A Retrospective Analysis Of The EBMT Chronic Malignancies Working Party by Scheid, Christof, de Wreede, Liesbeth, van Biezen, Anja, Göhring, Gudrun, Koenecke, Christian, Violin, Liisa, Maertens, Johan, Finke, Jürgen, Schaap, Nicolaas PM, Passweg, Jakob, Socie, Gerard, Beelen, Dietrich, Cornelissen, Jan, de Witte, Theo M., Kroeger, Nikolaus

“…Myelodysplastic syndromes are a heterogenous group of diseases with a very variable prognosis. Allogeneic stem cell transplantation is the only treatment…”
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Autologous Stem Cell Transplantation For Adult Burkitt Lymphoma In The Rituximab Era: A Retrospective Study Of The Lymphoma Working Party (LWP) Of The European Group For Blood and Marrow Transplantation (EBMT) by Ahmed, Syed, Boumendil, Ariane, Finel, Herve, Sureda, Anna, Schouten, Harry C., Mohty, Mohamad, van Imhoff, Guustaaf, Schroyens, Wilfried, Finke, Jurgen, Schaap, Nicolaas PM, Majolino, Ignazio, Bargetzi, Mario, Pogliani, Enrico Maria, Afanasyev, Boris, Dreger, Peter, Aljurf, Mahmoud D.

“…The role of autologous stem cell transplantation (ASCT) for Burkitt Lymphoma (BL) in adults in the era of modern intensive chemotherapeutic regimes remains to…”
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Thiotepa-Based Vs TBI-Based Myeloablative Conditioning Prior To Allogeneic Stem Cell Transplantation (HSCT) For Acute Myeloid Leukemia (AML) In First Complete Remission (CR1): A Retrospective Analysis From The ALWP Of The EBMT by Eder, Sandra, Labopin, Myriam, Arcese, William, Or, Reuven, Majolino, Ignazio, Bacigalupo, Andrea, de Rosa, Gennaro, Volin, Liisa, Beelen, Dietrich, Veelken, Hendrik, Schaap, Nicolaas PM, Kuball, Jurgen H, Cornelissen, Jan, Nagler, Arnon, Mohty, Mohamad

“…Thiotepa (N,N'N'-triethylenethiophosphoramide), which is an alkylating compound, has an antineoplastic activity and has been used in oncology (e.g. breast-,…”
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