Search Results - "Schaap, Iwan A.T."

Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System by Nawaz, Schanila, Sánchez, Paula, Schmitt, Sebastian, Snaidero, Nicolas, Mitkovski, Mišo, Velte, Caroline, Brückner, Bastian R., Alexopoulos, Ioannis, Czopka, Tim, Jung, Sang Y., Rhee, Jeong S., Janshoff, Andreas, Witke, Walter, Schaap, Iwan A.T., Lyons, David A., Simons, Mikael

“…During CNS development, oligodendrocytes wrap their plasma membrane around axons to generate multilamellar myelin sheaths. To drive growth at the leading edge…”
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Bending and Puncturing the Influenza Lipid Envelope by Li, Sai, Eghiaian, Frederic, Sieben, Christian, Herrmann, Andreas, Schaap, Iwan A.T.

“…Lysosomes, enveloped viruses, as well as synaptic and secretory vesicles are all examples of natural nanocontainers (diameter ≈ 100 nm) which specifically rely…”
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Kinesin Walks the Line: Single Motors Observed by Atomic Force Microscopy by Schaap, Iwan A.T., Carrasco, Carolina, de Pablo, Pedro J., Schmidt, Christoph F.

“…Motor proteins of the kinesin family move actively along microtubules to transport cargo within cells. How exactly a single motor proceeds on the 13 narrow…”
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Malaria Parasite Actin Polymerization and Filament Structure by Schmitz, Stephan, Schaap, Iwan A.T., Kleinjung, Jens, Harder, Simone, Grainger, Munira, Calder, Lesley, Rosenthal, Peter B., Holder, Anthony A., Veigel, Claudia

“…A novel form of acto-myosin regulation has been proposed in which polymerization of new actin filaments regulates motility of parasites of the apicomplexan…”
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Passage of soft pathogens through microfiltration membranes scales with transmembrane pressure by Helling, Alexander, Kubicka, Alexander, Schaap, Iwan A.T., Polakovic, Milan, Hansmann, Björn, Thiess, Holger, Strube, Jochen, Thom, Volkmar

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pH-Controlled Two-Step Uncoating of Influenza Virus by Li, Sai, Sieben, Christian, Ludwig, Kai, Höfer, Chris T., Chiantia, Salvatore, Herrmann, Andreas, Eghiaian, Frederic, Schaap, Iwan A.T.

“…Upon endocytosis in its cellular host, influenza A virus transits via early to late endosomes. To efficiently release its genome, the composite viral shell…”
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Swelling and Softening of the Cowpea Chlorotic Mottle Virus in Response to pH Shifts by Wilts, Bodo D., Schaap, Iwan A.T., Schmidt, Christoph F.

“…Cowpea chlorotic mottle virus (CCMV) forms highly elastic icosahedral protein capsids that undergo a characteristic swelling transition when the pH is raised…”
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Effect of Envelope Proteins on the Mechanical Properties of Influenza Virus by Schaap, Iwan A.T., Eghiaian, Frédéric, des Georges, Amédée, Veigel, Claudia

“…The envelope of the influenza virus undergoes extensive structural change during the viral life cycle. However, it is unknown how lipid and protein components…”
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Calcium Promotes the Formation of Syntaxin 1 Mesoscale Domains through Phosphatidylinositol 4,5-Bisphosphate by Milovanovic, Dragomir, Platen, Mitja, Junius, Meike, Diederichsen, Ulf, Schaap, Iwan A.T., Honigmann, Alf, Jahn, Reinhard, van den Bogaart, Geert

“…Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a minor component of total plasma membrane lipids, but it has a substantial role in the regulation of many…”
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Direct Measurement of Phage phi29 Stiffness Provides Evidence of Internal Pressure by Hernando-Pérez, Mercedes, Miranda, Roberto, Aznar, María, Carrascosa, José L., Schaap, Iwan A. T., Reguera, David, de Pablo, Pedro J.

“…Using AFM nanoindentation experiments, DNA‐full phi29 phage capsids are shown to be stiffer than when empty. The presence of counterions softens full viruses…”
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Elastic Response, Buckling, and Instability of Microtubules under Radial Indentation by Schaap, Iwan A.T., Carrasco, Carolina, de Pablo, Pedro J., MacKintosh, Frederick C., Schmidt, Christoph F.

“…We tested the mechanical properties of single microtubules by lateral indentation with the tip of an atomic force microscope. Indentations up to ∼3.6 nm, i.e.,…”
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Tau protein binding forms a 1 nm thick layer along protofilaments without affecting the radial elasticity of microtubules by Schaap, Iwan A.T., Hoffmann, Bernd, Carrasco, Carolina, Merkel, Rudolf, Schmidt, Christoph F.

“…Tau is one of the most abundant microtubule-associated proteins involved in kinetic stabilization and bundling of axonal microtubules. Although intense…”
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A high-speed vertical optical trap for the mechanical testing of living cells at piconewton forces by Bodensiek, Kai, Li, Weixing, Sánchez, Paula, Nawaz, Schanila, Schaap, Iwan A T

“…Although atomic force microscopy is often the method of choice to probe the mechanical response of (sub)micrometer sized biomaterials, the lowest force that…”
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Super-Resolution Optical Fluctuation Bio-Imaging with Dual-Color Carbon Nanodots by Chizhik, Anna M, Stein, Simon, Dekaliuk, Mariia O, Battle, Christopher, Li, Weixing, Huss, Anja, Platen, Mitja, Schaap, Iwan A. T, Gregor, Ingo, Demchenko, Alexander P, Schmidt, Christoph F, Enderlein, Jörg, Chizhik, Alexey I

“…Success in super-resolution imaging relies on a proper choice of fluorescent probes. Here, we suggest novel easily produced and biocompatible…”
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Photoluminescence of Carbon Nanodots: Dipole Emission Centers and Electron–Phonon Coupling by Ghosh, Siddharth, Chizhik, Anna M, Karedla, Narain, Dekaliuk, Mariia O, Gregor, Ingo, Schuhmann, Henning, Seibt, Michael, Bodensiek, Kai, Schaap, Iwan A. T, Schulz, Olaf, Demchenko, Alexander P, Enderlein, Jörg, Chizhik, Alexey I

“…Inorganic carbon nanomaterials, also called carbon nanodots, exhibit a strong photoluminescence with unusual properties and, thus, have been the focus of…”
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Cell visco-elasticity measured with AFM and optical trapping at sub-micrometer deformations by Nawaz, Schanila, Sánchez, Paula, Bodensiek, Kai, Li, Sai, Simons, Mikael, Schaap, Iwan A T

“…The measurement of the elastic properties of cells is widely used as an indicator for cellular changes during differentiation, upon drug treatment, or…”
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Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork by Aggarwal, Shweta, Snaidero, Nicolas, Pähler, Gesa, Frey, Steffen, Sánchez, Paula, Zweckstetter, Markus, Janshoff, Andreas, Schneider, Anja, Weil, Marie-Theres, Schaap, Iwan A T, Görlich, Dirk, Simons, Mikael

“…Rapid conduction of nerve impulses requires coating of axons by myelin. To function as an electrical insulator, myelin is generated as a tightly packed,…”
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Electromechanical Photophysics of GFP Packed Inside Viral Protein Cages Probed by Force‐Fluorescence Hybrid Single‐Molecule Microscopy by Strobl, Klara, Selivanovitch, Ekaterina, Ibáñez‐Freire, Pablo, Moreno‐Madrid, Francisco, Schaap, Iwan A. T., Delgado‐Buscalioni, Rafael, Douglas, Trevor, de Pablo, Pedro J.

“…Packing biomolecules inside virus capsids has opened new avenues for the study of molecular function in confined environments. These systems not only mimic the…”
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Fluorescence Tracking of Genome Release during Mechanical Unpacking of Single Viruses by Ortega-Esteban, Alvaro, Bodensiek, Kai, San Martín, Carmen, Suomalainen, Maarit, Greber, Urs F, de Pablo, Pedro J, Schaap, Iwan A. T

“…Viruses package their genome in a robust protein coat to protect it during transmission between cells and organisms. In a reaction termed uncoating, the virus…”
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The AP2 adaptor enhances clathrin coat stiffness by Lherbette, Michael, Redlingshöfer, Lisa, Brodsky, Frances M., Schaap, Iwan A. T., Dannhauser, Philip N.

“…Deformation of the plasma membrane into clathrin‐coated vesicles is a critical step in clathrin‐mediated endocytosis and requires the orchestrated assembly of…”
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