Search Results - "Schaade Lars"

Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2 by Hofmann, Natalie, Grossegesse, Marica, Neumann, Markus, Schaade, Lars, Nitsche, Andreas

“…High-throughput detection of neutralizing antibodies against SARS-CoV-2 presents a valuable tool for vaccine trials or investigations of population immunity…”
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Public Health Microbiology: Recent developments under Robert Koch’s genius loci by Mankertz, Annette, Schaade, Lars

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Perspective on Proteomics for Virus Detection in Clinical Samples by Grossegesse, Marica, Hartkopf, Felix, Nitsche, Andreas, Schaade, Lars, Doellinger, Joerg, Muth, Thilo

“…One of the most widely used methods to detect an acute viral infection in clinical specimens is diagnostic real-time polymerase chain reaction. However,…”
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Impact of the COVID-19 pandemic and associated non-pharmaceutical interventions on other notifiable infectious diseases in Germany: An analysis of national surveillance data during week 1–2016 – week 32–2020 by Ullrich, Alexander, Schranz, Madlen, Rexroth, Ute, Hamouda, Osamah, Schaade, Lars, Diercke, Michaela, Boender, T. Sonia

“…The COVID-19 pandemic and associated non-pharmaceutical interventions (NPIs) affect healthcare seeking behaviour, access to healthcare, test strategies,…”
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The impact of non-pharmaceutical interventions on COVID-19 epidemic growth in the 37 OECD member states by Pozo-Martin, Francisco, Weishaar, Heide, Cristea, Florin, Hanefeld, Johanna, Bahr, Thurid, Schaade, Lars, El Bcheraoui, Charbel

“…We estimated the impact of a comprehensive set of non-pharmeceutical interventions on the COVID-19 epidemic growth rate across the 37 member states of the…”
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Comparison of the Cowpox Virus and Vaccinia Virus Mature Virion Proteome: Analysis of the Species- and Strain-Specific Proteome by Doellinger, Joerg, Schaade, Lars, Nitsche, Andreas

“…Cowpox virus (CPXV) causes most zoonotic orthopoxvirus (OPV) infections in Europe and Northern as well as Central Asia. The virus has the broadest host range…”
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Evaluation of 11 commercially available PCR kits for the detection of monkeypox virus DNA, Berlin, July to September 2022 by Michel, Janine, Targosz, Angelina, Rinner, Thomas, Bourquain, Daniel, Brinkmann, Annika, Sacks, Jilian Amber, Schaade, Lars, Nitsche, Andreas

“…Before the international spread of monkeypox in May 2022, PCR kits for the detection of orthopoxviruses, and specifically monkeypox virus, were rarely…”
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Resource-efficient internally controlled in-house real-time PCR detection of SARS-CoV-2 by Michel, Janine, Neumann, Markus, Krause, Eva, Rinner, Thomas, Muzeniek, Therese, Grossegesse, Marica, Hille, Georg, Schwarz, Franziska, Puyskens, Andreas, Förster, Sophie, Biere, Barbara, Bourquain, Daniel, Domingo, Cristina, Brinkmann, Annika, Schaade, Lars, Schrick, Livia, Nitsche, Andreas

“…The reliable detection of SARS-CoV-2 has become one of the most important contributions to COVID-19 crisis management. With the publication of the first…”
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AmpliCoV: Rapid Whole-Genome Sequencing Using Multiplex PCR Amplification and Real-Time Oxford Nanopore MinION Sequencing Enables Rapid Variant Identification of SARS-CoV-2 by Brinkmann, Annika, Ulm, Sophie-Luisa, Uddin, Steven, Förster, Sophie, Seifert, Dominique, Oehme, Rainer, Corty, Merle, Schaade, Lars, Michel, Janine, Nitsche, Andreas

“…Since the emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) in December 2019, the scientific community has been sharing data on…”
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Replication of cowpox virus in macrophages is dependent on the host range factor p28/N1R by Bourquain, Daniel, Schrick, Livia, Tischer, Bernd Karsten, Osterrieder, Klaus, Schaade, Lars, Nitsche, Andreas

“…Zoonotic orthopoxvirus infections continue to represent a threat to human health. The disease caused by distinct orthopoxviruses differs in terms of symptoms…”
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RespiCoV: Simultaneous identification of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and 46 respiratory tract viruses and bacteria by amplicon-based Oxford-Nanopore MinION sequencing by Brinkmann, Annika, Uddin, Steven, Ulm, Sophie-Luisa, Pape, Katharina, Förster, Sophie, Enan, Khalid, Nourlil, Jalal, Krause, Eva, Schaade, Lars, Michel, Janine, Nitsche, Andreas

“…Since December 2019 the world has been facing the outbreak of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Identification of infected…”
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Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores by Grossegesse, Marica, Doellinger, Joerg, Fritsch, Annemarie, Laue, Michael, Piesker, Janett, Schaade, Lars, Nitsche, Andreas

“…The emergence of Variola virus-like viruses by natural evolution of zoonotic Orthopoxviruses, like Cowpox virus (CPXV), is a global health threat. The…”
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Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages by Bourquain, Daniel, Bodenstein, Clemens, Schürer, Stefanie, Schaade, Lars

“…Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main…”
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Nationally representative results on SARS-CoV-2 seroprevalence and testing in Germany at the end of 2020 by Neuhauser, Hannelore, Rosario, Angelika Schaffrath, Butschalowsky, Hans, Haller, Sebastian, Hoebel, Jens, Michel, Janine, Nitsche, Andreas, Poethko-Müller, Christina, Prütz, Franziska, Schlaud, Martin, Steinhauer, Hans W., Wilking, Hendrik, Wieler, Lothar H., Schaade, Lars, Liebig, Stefan, Gößwald, Antje, Grabka, Markus M., Zinn, Sabine, Ziese, Thomas

“…Pre-vaccine SARS-CoV-2 seroprevalence data from Germany are scarce outside hotspots, and socioeconomic disparities remained largely unexplored. The nationwide…”
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Flexible upscaling of laboratory PCR testing capacity at the Robert Koch Institute during the SARS-CoV-2 pandemic by Krause, Eva, Michel, Janine, Puyskens, Andreas, Hofmann, Natalie, Rinner, Thomas, Biere, Barbara, Dorner, Brigitte G, Skiba, Martin, Schaade, Lars, Nitsche, Andreas

“…Over the course of the COVID-19 pandemic, laboratories worldwide have been facing an unprecedented increase in demand for PCR testing because of the high…”
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Socioeconomic Differences in SARS-CoV-2 Infection and Vaccination in Germany: A Seroepidemiological Study After One Year of COVID-19 Vaccination Campaign by Bartig, Susanne, Beese, Florian, Wachtler, Benjamin, Grabka, Markus M., Mercuri, Elisabetta, Schmid, Lorenz, Schmid-Küpke, Nora Katharina, Schranz, Madlen, Goßner, Laura, Niehues, Wenke, Zinn, Sabine, Poethko-Müller, Christina, Schaade, Lars, Hövener, Claudia, Gößwald, Antje, Hoebel, Jens

“…Objective: To evaluate the socioeconomic patterns of SARS-CoV-2 antigen contacts through infection, vaccination or both (“hybrid immunity”) after 1 year of…”
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A Next-Generation Sequencing Approach Uncovers Viral Transcripts Incorporated in Poxvirus Virions by Grossegesse, Marica, Doellinger, Joerg, Haldemann, Berit, Schaade, Lars, Nitsche, Andreas

“…Transcripts are known to be incorporated in particles of DNA viruses belonging to the families of and , but the presence of transcripts in other DNA viruses,…”
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Lack of evidence for Schmallenberg virus infection in highly exposed persons, Germany, 2012 by Ducomble, Tanja, Wilking, Hendrik, Stark, Klaus, Takla, Anja, Askar, Mona, Schaade, Lars, Nitsche, Andreas, Kurth, Andreas

“…Schmallenberg virus, a novel orthobunyavirus, is spreading among ruminants, especially sheep, throughout Europe. To determine the risk for human infection, we…”
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Combined Proteomics/Genomics Approach Reveals Proteomic Changes of Mature Virions as a Novel Poxvirus Adaptation Mechanism by Grossegesse, Marica, Doellinger, Joerg, Tyshaieva, Alona, Schaade, Lars, Nitsche, Andreas

“…DNA viruses, like poxviruses, possess a highly stable genome, suggesting that adaptation of virus particles to specific cell types is not restricted to genomic…”
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Impfungen als Instrument der Pandemiebewältigung by Hildt, Eberhard, Schaade, Lars

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