Search Results - "Schaack, Grace A"
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Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks
Published in Nature communications (14-06-2022)“…Transmission of influenza A viruses (IAV) between hosts is subject to numerous physical and biological barriers that impose genetic bottlenecks, constraining…”
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Journal Article -
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Experimental Approaches to Identify Host Factors Important for Influenza Virus
Published in Cold Spring Harbor perspectives in medicine (01-12-2020)“…An ever-expanding toolkit of experimental methods provides the means to discover and characterize host factors important for influenza virus. Here, we describe…”
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Journal Article -
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Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection
Published in Cell host & microbe (13-09-2023)“…Host:pathogen interactions dictate the outcome of infection, yet the limitations of current approaches leave large regions of this interface unexplored. Here,…”
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Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry
Published in Journal of virology (01-07-2016)“…Phosphatidylserine (PtdSer) receptors that are responsible for the clearance of dying cells have recently been found to mediate enveloped virus entry. Ebola…”
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Journal Article -
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A Naturally Occurring Polymorphism in the Base of Sudan Virus Glycoprotein Decreases Glycoprotein Stability in a Species-Dependent Manner
Published in Journal of virology (25-08-2021)“…Sudan virus (SUDV) is one of five filoviruses that compose the genus that has been responsible for episodic outbreaks in Central Africa. While the SUDV…”
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Journal Article -
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Identifying Protein-Protein Interactions by Proximity Biotinylation with AirID and splitAirID
Published in Current protocols (01-03-2023)“…Proteins frequently function in high-order complexes. Defining protein-protein interactions is essential to acquiring a full understanding of their activity…”
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418. Comparison of the Abbott SARS-CoV-2 IgG and DiaSorin LIASON SARS-CoV-2 S1/S2 IgG Antibody Assays
Published in Open forum infectious diseases (31-12-2020)“…Abstract Background The Abbott Laboratories SARS-CoV-2 IgG assay and the DiaSorin LIASON SARS-CoV-2 S1/S2 IgG assay are both chemiluminescent immunoassays that…”
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Journal Article -
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IFITs in Context: Investigating Pro- and Anti-Viral Mechanisms of IFIT2 and IFIT3
Published 01-01-2023“…The IFITs (interferon-induced proteins with tetratricopeptide repeats) are important innate immune effectors with broad-spectrum antiviral activities. Previous…”
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Dissertation -
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689. Nasal versus Nasopharyngeal Sample Collection for Diagnostic Nucleic Acid Amplification Testing for Influenza A, Influenza B, and Respiratory Syncytial Viruses
Published in Open forum infectious diseases (31-12-2020)“…Abstract Background Nucleic acid amplification testing (NAAT) for influenza A virus (IAV), influenza B virus (IBV), and respiratory syncytial virus (RSV) is a…”
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Journal Article