Search Results - "Schönhofen, Patrícia"

Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer’s Disease Studies by de Medeiros, Liana M., De Bastiani, Marco A., Rico, Eduardo P., Schonhofen, Patrícia, Pfaffenseller, Bianca, Wollenhaupt-Aguiar, Bianca, Grun, Lucas, Barbé-Tuana, Florência, Zimmer, Eduardo R., Castro, Mauro A. A., Parsons, Richard B., Klamt, Fábio

“…Cholinergic transmission is critical to high-order brain functions such as memory, learning, and attention. Alzheimer’s disease (AD) is characterized by…”
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RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells by Lopes, Fernanda M., da Motta, Leonardo Lisbôa, De Bastiani, Marco A., Pfaffenseller, Bianca, Aguiar, Bianca W., de Souza, Luiz F., Zanatta, Geancarlo, Vargas, Daiani M., Schönhofen, Patrícia, Londero, Giovana F., de Medeiros, Liana M., Freire, Valder N., Dafre, Alcir L., Castro, Mauro A. A., Parsons, Richard B., Klamt, Fabio

“…Research on Parkinson’s disease (PD) and drug development is hampered by the lack of suitable human in vitro models that simply and accurately recreate the…”
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Effects of the AMPAR Antagonist, Perampanel, on Cognitive Function in Rats Exposed to Neonatal Iron Overload by da Silva, José, de Souza, Lariza Oliveira, Severo, Maria Paula Arakaki, Rodrigues, Sarah Luize Camargo, Molz, Patrícia, Schonhofen, Patrícia, Herlinger, Alice Laschuk, Schröder, Nadja

“…Iron accumulation has been associated with the pathogenesis of neurodegenerative diseases and memory decline. As previously described by our research group,…”
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Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System by Schonhofen, Patrícia, Bristot, Ivi Juliana, Crippa, José Alexandre, Hallak, Jaime Eduardo Cecílio, Zuardi, Antônio Waldo, Parsons, Richard B., Klamt, Fábio

“…The endocannabinoid retrograde signaling pathway is widely expressed in the central nervous system, where it plays major roles in regulating synaptic…”
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Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins by Schönhofen, Patrícia, de Medeiros, Liana M., Bristot, Ivi Juliana, Lopes, Fernanda M., De Bastiani, Marco A., Kapczinski, Flávio, Crippa, José Alexandre S., Castro, Mauro Antônio A., Parsons, Richard B., Klamt, Fábio

“…Cannabidiol (CBD), one of the most abundant Cannabis sativa -derived compounds, has been implicated with neuroprotective effect in several human pathologies…”
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Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration by Schönhofen, Patrícia, de Medeiros, Liana Marengo, Chatain, Carolina Piletti, Bristot, Ivi Juliana, Klamt, Fábio

“…Cofilin-1 protein, which main function is to regulate actin cytoskeleton dynamics, appears to be involved with many steps in the neurotoxicity processes found…”
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Cannabinoid.Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System by Schonhofen, Patrícia, Bristot, Ivi Juliana, Crippa, José Alexandre, Hallak, Jaime Eduardo Cecílio, Zuardi, Antônio Waldo, Parsons, Richard B, Klamt, Fábio

“…The endocannabinoid retrograde signaling pathway is widely expressed in the central nervous system, where it plays major roles in regulating synaptic…”
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Long-term vitamin A supplementation at therapeutic doses induces mitochondrial electrons transfer chain (METC) impairment and increased mitochondrial membrane-enriched fraction (MMEF) 3-nitrotyrosine on rat heart by da Rocha, Ricardo F, de Oliveira, Marcos Roberto, Schonhofen, Patrícia, Schnorr, Carlos Eduardo, Dal Pizzol, Felipe, Moreira, José Cláudio F

“…The aim of the present study was to compare electrons flux and oxidative/nitrosative stress parameters on the heart among rats supplemented with vitamin A and…”
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Vitamin A supplementation for different periods alters rat vascular redox parameters by da Rocha, Ricardo Fagundes, de Oliveira, Marcos Roberto, Schonhofen, Patrícia, De Bastiani, Marco Antônio, Schnorr, Carlos Eduardo, Klamt, Fábio, Dal Pizzol, Felipe, Moreira, José Claudio Fonseca

“…Vitamin A plays physiological and antioxidants properties and is associated with protective effects on arterial level. However, deleterious effects have been…”
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