Search Results - "Schömig, E"

Aspirin induces nitric oxide release from vascular endothelium: a novel mechanism of action by Taubert, D, Berkels, R, Grosser, N, Schröder, H, Gründemann, D, Schömig, E

“…The study was designed to test the hypothesis that aspirin may stimulate nitric oxide (NO) release from vascular endothelium, a pivotal factor for maintenance…”
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Extraneuronal monoamine transporter and organic cation transporters 1 and 2: a review of transport efficiency by Schömig, E, Lazar, A, Gründemann, D

“…The extraneuronal monoamine transporter (EMT) corresponds to the classical steroid-sensitive monoamine transport mechanism that was first described as…”
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Effect of an Antiretroviral Regimen Containing Ritonavir Boosted Lopinavir on Intestinal and Hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected Patients by Wyen, C, Fuhr, U, Frank, D, Aarnoutse, RE, Klaassen, T, Lazar, A, Seeringer, A, Doroshyenko, O, Kirchheiner, JC, Abdulrazik, F, Schmeisser, N, Lehmann, C, Hein, W, Schömig, E, Burger, DM, Fätkenheuer, G, Jetter, A

“…This study aimed to quantify the inhibition of cytochrome P450 (CYP3A), CYP2D6, and P‐glycoprotein in human immunodeficiency virus (HIV)‐infected patients…”
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Organic cation transporters OCT1 and OCT2 determine the accumulation of lamivudine in CD4 cells of HIV-infected patients by Jung, N., Lehmann, C., Rubbert, A., Schömig, E., Fätkenheuer, G., Hartmann, P., Taubert, D.

“…Purpose Identifying factors that determine concentrations of antiretroviral drugs in CD4 cells are important for improving therapeutic efficacy. Experimental…”
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Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter by Gründemann, Dirk, Schechinger, Birgit, Rappold, Gudrun, Schömig, Edgar

“…Catecholaminergic signaling regulates various physiological functions, such as blood pressure and is implicated in drug dependence, affective disorders and…”
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Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn’s disease by Taubert, D, Grimberg, G, Jung, N, Rubbert, A, Schömig, E

“…Considering that maximal levels of ET found in tissues and in common foods are in the nanomolar to low micromolar range, 5 our data suggest that carriers of…”
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Paramount levels of ergothioneine transporter SLC22A4 mRNA in boar seminal vesicles and cross-species analysis of ergothioneine and glutathione in seminal plasma by Nikodemus, D, Lazic, D, Bach, M, Bauer, T, Pfeiffer, C, Wiltzer, L, Lain, E, Schömig, E, Gründemann, D

“…Ergothioneine (ET) is a unique natural antioxidant which mammalia acquire exclusively from their food. Recently, we have discovered an ET transporter (ETT;…”
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Selective substrates for non-neuronal monoamine transporters by Gründemann, D, Liebich, G, Kiefer, N, Köster, S, Schömig, E

“…The recently identified transport proteins organic cation transporter 1 (OCT1), OCT2, and extraneuronal monoamine transporter (EMT) accept dopamine,…”
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Are we making efficient use of clopidogrel? by Kastrati, A, Schömig, A, Schömig, E

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Clopidogrel resistance caused by a failure to metabolize clopidogrel into its metabolites by HEESTERMANS, A. A. C. M., VAN WERKUM, J. W., SCHÖMIG, E., TEN BERG, J. M., TAUBERT, D.

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Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters by Martel, F, Gründemann, D, Calhau, C, Schömig, E

“…The aim of this work was to characterise the intestinal absorption of organic cations, by testing the possibility of involvement of known members of the…”
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Primary structure and functional expression of the apical organic cation transporter from kidney epithelial LLC-PK1 cells by Grundemann, D. (University of Heidelberg, Germany.), Babin-Ebell, J, Martel, F, Ording, N, Schmidt, A, Schomig, E

“…Renal secretion of organic cations involves at least two distinct transporters, located in the basolateral and apical membranes of proximal tubule cells…”
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Tannic acid in plant dust causes airway obstruction by Taubert, D, Grimberg, G, Schömig, E

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Acute effects of glucose and insulin on vascular endothelium by TAUBERT, D, ROSENKRANZ, A, BERKELS, R, ROESEN, R, SCHÖMIG, E

“…Chronic exposure to high concentrations of glucose has consistently been demonstrated to impair endothelium-dependent, nitric oxide (NO)-mediated vasodilation…”
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Catecholamine transport by the organic cation transporter type 1 (OCT1) by Breidert, Tilo, Spitzenberger, Folker, Gründemann, Dirk, Schömig, Edgar

“…1 Liver and kidney extract adrenaline and noradrenaline from the circulation by a mechanism which does not seem to be one of the classical catecholamine…”
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Transport of Monoamine Transmitters by the Organic Cation Transporter Type 2, OCT2 by Gründemann, Dirk, Köster, Sandra, Kiefer, Nicholas, Breidert, Tilo, Engelhardt, Martin, Spitzenberger, Folker, Obermüller, Nicholas, Schömig, Edgar

“…The recently cloned apical renal transport system for organic cations (OCT2) exists in dopamine-rich tissues such as kidney and some brain areas (Gründemann,…”
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Regulation of human extraneuronal monoamine transporter (hEMT) expressed in HEK293 cells by intracellular second messenger systems by Martel, F, Keating, E, Calhau, C, Gründemann, D, Schömig, E, Azevedo, I

“…Several transmembrane transporters of organic compounds are regulated by phosphorylation/dephosphorylation mechanisms. The aim of this study was to investigate…”
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Molecular cloning and characterization of two novel transport proteins from rat kidney by Schömig, Edgar, Spitzenberger, Folker, Engelhardt, Martin, Martel, Fátima, Örding, Nicola, Gründemann, Dirk

“…The recent cloning of renal transport systems for organic anions and cations (OAT1, OCT1, and OCT2) opened the possibility to search, via polymerase chain…”
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Impact of P-glycoprotein on clopidogrel absorption by Taubert, Dirk, Beckerath, Nicolas, Grimberg, Gundula, Lazar, Andreas, Jung, Norma, Goeser, Tobias, Kastrati, Adnan, Schömig, Albert, Schömig, Edgar

“…Objective The antiplatelet activity of clopidogrel is characterized by considerable interindividual differences. Variable intestinal absorption is suggested to…”
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Increased ergothioneine tissue concentrations in carriers of the Crohn's disease risk-associated 503F variant of the organic cation transporter OCTN1 by Taubert, D, Jung, N, Goeser, T, Schömig, E

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