Search Results - "Schäfer, Stephan"
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Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-2016)“…Chemotherapy-induced peripheral neuropathic pain (CIPNP) is a severe dose- and therapy-limiting side effect of widely used cytostatics that is particularly…”
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Dietary Potassium Supplementation Reduces Chronic Kidney Lesions Independent of Blood Pressure in Deoxycorticosterone-Acetate and High Sodium Chloride-Treated Mice
Published in International journal of molecular sciences (01-12-2023)“…We have previously shown that an excess of deoxycorticosterone acetate and high sodium chloride intake (DOCA/salt) in one-renin gene mice induces a high…”
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3
miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…A global understanding of miRNA function in EGFR signaling pathways may provide insights into improving the management of KRAS-mutant lung cancers, which…”
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4
Comparison of Blood Collection Tubes from Three Different Manufacturers for the Collection of Cell-Free DNA for Liquid Biopsy Mutation Testing
Published in The Journal of molecular diagnostics : JMD (01-09-2017)“…The improvement in sensitive techniques has allowed the detection of tumor-specific aberrations in circulating tumor (ct) DNA. Amplification-refractory…”
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Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1
Published in Blood (04-02-2021)“…Richter’s transformation (RT) is an aggressive lymphoma that occurs upon progression from chronic lymphocytic leukemia (CLL). Transformation has been…”
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Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability?
Published in Talanta (Oxford) (01-03-2020)“…The impact of preanalytical sample handling on lipid stability has been assessed in human plasma using targeted LC-MS/MS quantification of endocannabinoids,…”
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The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue
Published in Frontiers in immunology (01-10-2018)“…Macrophages are highly versatile cells, which acquire, depending on their microenvironment, pro- (M1-like), or antiinflammatory (M2-like) phenotypes. Here, we…”
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Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type?
Published in Oncotarget (15-09-2015)“…Lung adenosquamous carcinoma is a particular subtype of non-small cell lung carcinoma that is defined by the coexistence of adenocarcinoma and squamous cell…”
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Current PD-L1 immunohistochemistry for non-small cell lung cancer
Published in Journal of thoracic disease (01-03-2018)Get full text
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10
Chemical p38 MAP kinase inhibition constrains tissue inflammation and improves antibiotic activity in Mycobacterium tuberculosis-infected mice
Published in Scientific reports (12-08-2020)“…Host-modulating therapies have become an important focus in the development of novel concepts for improved management of tuberculosis (TB). Previous in vitro…”
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Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations
Published in Molecular oncology (01-11-2018)“…Lung adenocarcinoma (LUAD) is the most prevalent subtype of non‐small cell lung cancer. Despite the development of novel targeted and immune therapies, the…”
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Rapid Large-Scale COVID-19 Testing during Shortages
Published in Diagnostics (Basel) (08-07-2020)“…The Coronavirus disease 2019 (COVID-19) pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has resulted in economic and social…”
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The use of microspectrofluorimetry for the characterization of lake pigments
Published in Talanta (Oxford) (15-01-2008)“…In this paper, the potential of confocal microfluorescence spectroscopy is explored for the characterization of selected red lake pigments and paints based on…”
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LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells
Published in Scientific reports (31-08-2017)“…The epigenetic writer lysine-specific demethylase 1 (LSD1) is aberrantly upregulated in many cancer types and its overexpression correlates with poor survival…”
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The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP)
Published in Neuropharmacology (01-04-2020)“…Oxidized lipids play an important role in pain processing by modulation of the activity of sensory neurons. However, the role of many signalling lipids that do…”
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Author Correction: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells
Published in Scientific reports (01-11-2018)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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Proteomics applied to the authentication of fish glue: application to a 17th century artwork sample
Published in Analyst (London) (01-01-2013)“…This work provides the first identification of fish glue from a few micrograms of a 17(th) century artwork sample using an adapted proteomics approach. Fish…”
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The Heart Communicates with the Endothelium through the Guanylyl Cyclase-A Receptor: Acute Handling of Intravascular Volume in Response to Volume Expansion
Published in Endocrinology (Philadelphia) (01-08-2008)“…Atrial natriuretic peptide (ANP) regulates arterial blood pressure and volume. Its guanylyl cyclase-A (GC-A) receptor is expressed in vascular endothelium and…”
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19
Preclinical studies reveal that LSD 1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations
Published in Molecular oncology (01-11-2018)“…Lung adenocarcinoma ( LUAD ) is the most prevalent subtype of non‐small cell lung cancer. Despite the development of novel targeted and immune therapies, the…”
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20
High sensitivity of PD-L1 analysis from pleural effusion in nonsmall cell lung cancer
Published in ERJ open research (01-01-2021)“…Programmed cell death protein 1 (PD-1)/programmed cell death protein ligand 1 (PD-L1) immune checkpoint inhibitors have been approved for monotherapy of…”
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