Search Results - "Schäfer, Jonas"

Validation of new tablet-based problem-solving tasks in primary school students by Schäfer, Jonas, Reuter, Timo, Leuchter, Miriam, Karbach, Julia

“…Problem-solving is an important skill that is associated with reasoning abilities, action control and academic success. Nevertheless, empirical evidence on…”
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Prospective Assessment of Treatment-Induced Liver Injury as a Cause of Diffuse Pathologic Hepatic Enhancement in Contrast-Enhanced Ultrasound by Wiemers, Hannah, Burchert, Andreas, Michel, Christian, Sohlbach, Kristina, Schäfer, Jonas, Neubauer, Andraes, Görg, Christian, Trenker, Corinna

“…A hypo-enhancement of the liver in contrast-enhanced ultrasound (CEUS), pathologic one-minute hepatic enhancement (pOMHE), was recently observed in 70% of…”
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Leaflet-Dependent Distribution of PtdIns[4,5]P2 in Supported Model Membranes by Schäfer, Jonas, Nehls, Jessica, Schön, Markus, Mey, Ingo, Steinem, Claudia

“…Supported planar lipid bilayers (SLBs) prepared by spreading of unilamellar vesicles on hydrophilic substrates such as silicon dioxide are frequently used to…”
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Pathologic Hepatic Contrast-Enhanced Ultrasound Pattern in Patients Undergoing Allogeneic Stem Cell Transplantation by Trenker, Corinna, Burchert, Andreas, Schumacher, Caren, Schäfer, Jonas A., Dohse, Marius, Timmesfeld, Nina, Neubauer, Andreas, Sohlbach, Kristina, Michel, Christian, Görg, Christian

“…Veno-occlusive disease (VOD) is a severe complication of allogeneic stem cell transplantation (allo-SCT). Its diagnosis is difficult, and ultrasound (US) has…”
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Cell–Substrate Dynamics of the Epithelial-to-Mesenchymal Transition by Baronsky, Thilo, Ruhlandt, Daja, Brückner, Bastian Rouven, Schäfer, Jonas, Karedla, Narain, Isbaner, Sebastian, Hähnel, Dirk, Gregor, Ingo, Enderlein, Jörg, Janshoff, Andreas, Chizhik, Alexey I

“…The biological process of the epithelial-to-mesenchymal transition (EMT) allows epithelial cells to enhance their migratory and invasive behavior and plays a…”
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Real‐world effectiveness of first‐line azacitidine or decitabine with or without venetoclax in acute myeloid leukemia patients unfit for intensive therapy by Acker, Fabian, Chromik, Jörg, Tiedjen, Emily, Wolf, Sebastian, Vischedyk, Jonas B., Makowka, Philipp, Enßle, Julius C., Kouidri, Khouloud, Sebastian, Martin, Steffen, Björn, Oellerich, Thomas, Serve, Hubert, Neubauer, Andreas, Schäfer, Jonas A., Bittenbring, Jörg T.

“…Background First‐line treatment in patients with acute myeloid leukemia (AML) unfit for intensive therapy is the combination of a hypomethylating agent (HMA)…”
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Idasanutlin Plus Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia: Results of the MIRROS Trial by Konopleva, Marina Y., Röllig, Christoph, Cavenagh, Jamie, Deeren, Dries, Girshova, Larisa, Krauter, Jürgen, Martinelli, Giovanni, Montesinos, Pau, Schäfer, Jonas A., Ottmann, Oliver, Petrini, Mario, Pigneux, Arnaud, Rambaldi, Alessandro, Recher, Christian, Rodriguez-Veiga, Rebeca, Taussig, David, Vey, Norbert, Yoon, Sung-Soo, Ott, Marion, Muehlbauer, Susanne, Beckermann, Benjamin M., Catalani, Olivier, Genevray, Magali, Mundt, Kirsten, Jamois, Candice, Fenaux, Pierre, Wei, Andrew H.

“…The phase III MIRROS trial (NCT02545283) evaluated the efficacy and safety of the small-molecule MDM2 antagonist idasanutlin plus cytarabine in patients with…”
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Combined Focused Next-Generation Sequencing Assays to Guide Precision Oncology in Solid Tumors: A Retrospective Analysis from an Institutional Molecular Tumor Board by Tarawneh, Thomas S., Rodepeter, Fiona R., Teply-Szymanski, Julia, Ross, Petra, Koch, Vera, Thölken, Clemens, Schäfer, Jonas A., Gremke, Niklas, Mack, Hildegard I. D., Gold, Judith, Riera-Knorrenschild, Jorge, Wilhelm, Christian, Rinke, Anja, Middeke, Martin, Klemmer, Andreas, Romey, Marcel, Hattesohl, Akira, Jesinghaus, Moritz, Görg, Christian, Figiel, Jens, Chung, Ho-Ryun, Wündisch, Thomas, Neubauer, Andreas, Denkert, Carsten, Mack, Elisabeth K. M.

“…Background: Increasing knowledge of cancer biology and an expanding spectrum of molecularly targeted therapies provide the basis for precision oncology…”
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The Nuclear Proteins TP73 and CUL4A Confer Resistance to Cytarabine by Induction of Translesion DNA Synthesis via Mono‐ubiquitination of PCNA by Rehberger, Miriam, Schäfer, Jonas A., Krampitz, Anna‐Maria, Bretz, Anne Catherine, Jost, Lukas, Haferlach, Torsten, Stiewe, Thorsten, Neubauer, Andreas

“…Resistance to cytarabine is a key problem in the treatment of acute myeloid leukemia (AML). To understand the molecular biology of resistance to cytarabine, a…”
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Monitoring the dynamics of clonal tumour evolution in vivo using secreted luciferases by Charles, Joël P., Fuchs, Jeannette, Hefter, Mirjam, Vischedyk, Jonas B., Kleint, Maximilian, Vogiatzi, Fotini, Schäfer, Jonas A., Nist, Andrea, Timofeev, Oleg, Wanzel, Michael, Stiewe, Thorsten

“…Tumours are heterogeneous cell populations that undergo clonal evolution during tumour progression, metastasis and response to therapy. Short hairpin RNAs…”
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Specificity of Collybistin-Phosphoinositide Interactions by Ludolphs, Michaela, Schneeberger, Daniela, Soykan, Tolga, Schäfer, Jonas, Papadopoulos, Theofilos, Brose, Nils, Schindelin, Hermann, Steinem, Claudia

“…The regulatory protein collybistin (CB) recruits the receptor-scaffolding protein gephyrin to mammalian inhibitory glycinergic and GABAergic postsynaptic…”
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A memory-efficient finite volume method for advection-diffusion-reaction systems with nonsmooth sources by Schäfer, Jonas, Huang, Xuan, Kopecz, Stefan, Birken, Philipp, Gobbert, Matthias K., Meister, Andreas

“…We present a parallel matrix‐free implicit finite volume scheme for the solution of unsteady three‐dimensional advection‐diffusion‐reaction equations with…”
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Cooling Nanorotors by Elliptic Coherent Scattering by Schäfer, Jonas, Rudolph, Henning, Hornberger, Klaus, Stickler, Benjamin A

“…Simultaneously cooling the rotational and translational motion of nanoscale dielectrics into the quantum regime is an open task of great importance for sensing…”
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Executive functions and problem-solving—The contribution of inhibition, working memory, and cognitive flexibility to science problem-solving performance in elementary school students by Schäfer, Jonas, Reuter, Timo, Leuchter, Miriam, Karbach, Julia

“…•Executive functions contribute to problem-solving in six- to eight-year-olds.•Working memory and cognitive flexibility contribute to…”
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Domain‐specific knowledge and domain‐general abilities in children's science problem‐solving by Schäfer, Jonas, Reuter, Timo, Karbach, Julia, Leuchter, Miriam

“…Background Problem‐solving in early and middle childhood is of high relevance for cognitive developmental research and educational support. Previous research…”
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Patient-Centeredness in Older Adults With Multimorbidity: Results of an Online Expert Delphi Study by Kivelitz, Laura, Schäfer, Jonas, Kanat, Manuela, Mohr, Jil, Glattacker, Manuela, Voigt-Radloff, Sebastian, Dirmaier, Jörg

“…Abstract Background and Objectives Older adults suffering from multimorbidity represent a priority target group for patient-centeredness (PC). We aimed to…”
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Neuroligin-2 dependent conformational activation of collybistin reconstituted in supported hybrid membranes by Schäfer, Jonas, Förster, Lucas, Mey, Ingo, Papadopoulos, Theofilos, Brose, Nils, Steinem, Claudia

“…The assembly of the postsynaptic transmitter sensing machinery at inhibitory nerve cell synapses requires the intimate interplay between cell adhesion…”
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Leaflet-Dependent Distribution of PtdIns[4,5]P 2 in Supported Model Membranes by Schäfer, Jonas, Nehls, Jessica, Schön, Markus, Mey, Ingo, Steinem, Claudia

“…Supported planar lipid bilayers (SLBs) prepared by spreading of unilamellar vesicles on hydrophilic substrates such as silicon dioxide are frequently used to…”
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Updated Results from a Phase I Dose Escalation Study of the Rapidly-Switchable Universal CAR-T Therapy UniCAR-T-CD123 in Relapsed/Refractory AML by Wermke, Martin, Metzelder, Stephan, Kraus, Sabrina, Sala, Elisa, Vucinic, Vladan, Fiedler, Walter, Wetzko, Katrin, Schäfer, Jonas, Goebeler, Maria-Elisabeth, Koedam, Jan, Franke, Kristin, Vänskä, Matti, Ehninger, Armin, Cartellieri, Marc, Ehninger, Gerhard, Maniar, Tapan

“…Introduction CAR-T efficacy in AML has been limited by a lack of ideal target antigens as well as the aggressive and resistant nature of disease. CD123…”
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Palliative care for patients with heart failure: facilitators and barriers - a cross sectional survey of German health care professionals by Ziehm, Jeanette, Farin, Erik, Schäfer, Jonas, Woitha, Kathrin, Becker, Gerhild, Köberich, Stefan

“…Compared to patients with cancer, heart failure patients are seldom candidates for palliative care. Numerous studies have investigated reasons why heart…”
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