Search Results - "Schäfer, Anima M."
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Establishment and Validation of Competitive Counterflow as a Method To Detect Substrates of the Organic Anion Transporting Polypeptide 2B1
Published in Molecular pharmaceutics (03-12-2018)“…The organic anion transporting polypeptide (OATP) 2B1 is ubiquitously expressed and known to facilitate cellular entry. It is widely accepted that transport…”
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Expression and Function of Organic Anion Transporting Polypeptides in the Human Brain: Physiological and Pharmacological Implications
Published in Pharmaceutics (04-06-2021)“…The central nervous system (CNS) is an important pharmacological target, but it is very effectively protected by the blood–brain barrier (BBB), thereby…”
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A face‐to‐face comparison of the BBB cell models hCMEC/D3 and hBMEC for their applicability to adenoviral expression of transporters
Published in Journal of neurochemistry (01-09-2024)“…The blood–brain barrier (BBB) is a structure mainly formed by brain capillary endothelial cells (BCEC) whose role is to regulate the exchange of compounds…”
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OATP1A2 and OATP2B1 Are Interacting with Dopamine-Receptor Agonists and Antagonists
Published in Molecular pharmaceutics (01-06-2020)“…Interaction with the dopaminergic system in the central nervous system is either therapeutically intended or it is a side effect. In both cases,…”
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Influence of Slco2b1‐knockout and SLCO2B1‐humanization on coproporphyrin I and III levels in rats
Published in British journal of pharmacology (01-01-2024)“…Background and Purpose Coproporphyrin (CP) I and III are byproducts of haem synthesis currently investigated as biomarkers for drug–drug interactions involving…”
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Hyperforin-Induced Activation of the Pregnane X Receptor Is Influenced by the Organic Anion-Transporting Polypeptide 2B1
Published in Molecular pharmacology (01-03-2019)“…The herbal remedy St. John's wort (SJW) is used in the treatment of mild depressive symptoms and is known for its drug-drug interaction potential when enhanced…”
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Simultaneous quantification of atorvastatin, erlotinib and OSI-420 in rat serum and liver microsomes using a novel liquid chromatography-mass spectrometry method
Published in Journal of pharmaceutical and biomedical analysis (30-11-2023)“…Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor used in the treatment of cancer. Atorvastatin is a statin commonly applied to treat…”
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Constituents of Passiflora incarnata, but Not of Valeriana officinalis, Interact with the Organic Anion Transporting Polypeptides (OATP)2B1 and OATP1A2
Published in Planta medica (01-02-2022)“…Herbal medication used in the treatment of sleep disorders and anxiety often contain extracts of or . Valerenic acid in and apigenin, orientin, and vitexin in…”
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