Search Results - "Scavuzzo, A"

Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis by Singh, Ravi K., Xia, Zheng, Bland, Christopher S., Kalsotra, Auinash, Scavuzzo, Marissa A., Curk, Tomaz, Ule, Jernej, Li, Wei, Cooper, Thomas A.

“…Alternative splicing plays important regulatory roles during periods of physiological change. During development, a large number of genes coordinately express…”
Get full text

Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis by Scavuzzo, Marissa A., Hill, Matthew C., Chmielowiec, Jolanta, Yang, Diane, Teaw, Jessica, Sheng, Kuanwei, Kong, Yuelin, Bettini, Maria, Zong, Chenghang, Martin, James F., Borowiak, Malgorzata

“…Decoding the molecular composition of individual Ngn3  + endocrine progenitors (EPs) during pancreatic morphogenesis could provide insight into the mechanisms…”
Get full text

Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development by Giudice, Jimena, Xia, Zheng, Wang, Eric T., Scavuzzo, Marissa A., Ward, Amanda J., Kalsotra, Auinash, Wang, Wei, Wehrens, Xander H. T., Burge, Christopher B., Li, Wei, Cooper, Thomas A.

“…During postnatal development the heart undergoes a rapid and dramatic transition to adult function through transcriptional and post-transcriptional mechanisms,…”
Get full text

Human pancreatic microenvironment promotes β-cell differentiation via non-canonical WNT5A/JNK and BMP signaling by Chmielowiec, Jolanta, Szlachcic, Wojciech J., Yang, Diane, Scavuzzo, Marissa A., Wamble, Katrina, Sarrion-Perdigones, Alejandro, Sabek, Omaima M., Venken, Koen J. T., Borowiak, Malgorzata

“…In vitro derivation of pancreatic β-cells from human pluripotent stem cells holds promise as diabetes treatment. Despite recent progress, efforts to generate…”
Get full text

Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA by Scavuzzo, Marissa A., Chmielowiec, Jolanta, Yang, Diane, Wamble, Katrina, Chaboub, Lesley S., Duraine, Lita, Tepe, Burak, Glasgow, Stacey M., Arenkiel, Benjamin R., Brou, Christel, Deneen, Benjamin, Borowiak, Malgorzata

“…Notch is activated globally in pancreatic progenitors; however, for progenitors to differentiate into endocrine cells, they must escape Notch activation to…”
Get full text

Prognostic significance of Fuhrman grade and age for cancer-specific and overall survival in patients with papillary renal cell carcinoma: results of an international multi-institutional study on 2189 patients by Borgmann, H., Musquera, M., Haferkamp, A., Vilaseca, A., Klatte, T., Shariat, S. F., Scavuzzo, A., Jimenez Rios, M. A., Wolff, I., Capitanio, U., Dell’Oglio, P., Krabbe, L. M., Herrmann, E., Ecke, T., Vergho, D., Huck, N., Wagener, N., Pahernik, S., Zastrow, S., Wirth, M., Surcel, C., Mirvald, C., Prochazkova, K., Hutterer, G., Zigeuner, R., Cindolo, L., Hora, M., Stief, C. G., May, M., Brookman-May, S. D.

“…Purpose Because the prognostic impact of the clinical and pathological features on cancer-specific survival (CSS) and overall survival (OS) in patients with…”
Get full text

Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases by Yang, Diane, Scavuzzo, Marissa A, Chmielowiec, Jolanta, Sharp, Robert, Bajic, Aleksandar, Borowiak, Malgorzata

“…Efficient gene editing is essential to fully utilize human pluripotent stem cells (hPSCs) in regenerative medicine. Custom endonuclease-based gene targeting…”
Get full text

ASIL-D automotive-grade microcontroller in 28nm FD-SOI with full-OTA capable 21MB embedded PCM memory and highly scalable power management by Grossier, N., Disegni, F., Ventre, A., Barcella, A., Mariani, R., Marino, V., Mazzara, S., Scavuzzo, A., Bansal, M., Soni, B., Anand, A., Banzal, S., Joshi, D., Narwal, R., Niranjani, M., Trivedi, K., Ferreira, P., Ranica, R., Vullo, L., Cathelin, A., Maurelli, A., Pezzini, S., Peri, M.

“…This paper proposes the first ever MCU product implementing an ASIL-D automotive grade 0 capable microcontroller with 21MB embedded phase-change memory (PCM)…”
Get full text

Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells by Scavuzzo, Marissa A., Yang, Diane, Borowiak, Malgorzata

“…Replacement of lost beta cells in patients with diabetes has the potential to alleviate them of their disease, yet current protocols to make beta cells are…”
Get full text

Deep into the niche: Deciphering local endoderm‐microenvironment interactions in development, homeostasis, and disease of pancreas and intestine by Szlachcic, Wojciech J., Letai, Katherine C., Scavuzzo, Marissa A., Borowiak, Malgorzata

“…Unraveling molecular and functional heterogeneity of niche cells within the developing endoderm could resolve mechanisms of tissue formation and maturation…”
Get full text

VID-01.06 Laparoscopic Partial Cystectomy for Bladder Leiomyoma: Case Report by Saita, A, Scavuzzo, A, Puglisi, M, Falsaperla, M, Motta, M, Morgia, G

Get full text

Pervasive environmental chemicals impair oligodendrocyte development by Cohn, Erin F., Clayton, Benjamin L. L., Madhavan, Mayur, Lee, Kristin A., Yacoub, Sara, Fedorov, Yuriy, Scavuzzo, Marissa A., Paul Friedman, Katie, Shafer, Timothy J., Tesar, Paul J.

“…Exposure to environmental chemicals can impair neurodevelopment, and oligodendrocytes may be particularly vulnerable, as their development extends from…”
Get full text

A dormant T‐cell population with autoimmune potential exhibits low self‐reactivity and infiltrates islets in type 1 diabetes by Kong, Yuelin, Jing, Yi, Allard, Denise, Scavuzzo, Marissa A., Sprouse, Maran L., Borowiak, Malgorzata, Bettini, Matthew L., Bettini, Maria

“…The contribution of low‐affinity T cells to autoimmunity in the context of polyclonal T‐cell responses is understudied due to the limitations in their capture…”
Get full text

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells by Bettini, Maria, Scavuzzo, Marissa A, Liu, Baoyu, Kolawole, Elizabeth, Guo, Lin, Evavold, Brian D, Borowiak, Malgorzata, Bettini, Matthew L

“…Type 1 diabetes is an autoimmune-mediated disease that culminates in the targeted destruction of insulin-producing β-cells. CD4 responses in NOD mice are…”
Get full text

Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity by Sprouse, Maran L, Shevchenko, Ivan, Scavuzzo, Marissa A, Joseph, Faith, Lee, Thomas, Blum, Samuel, Borowiak, Malgorzata, Bettini, Matthew L, Bettini, Maria

“…Regulatory T cells (Tregs) use a distinct TCR repertoire and are more self-reactive compared with conventional T cells. However, the extent to which TCR…”
Get full text

Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function by Allan, Kevin C., Hu, Lucille R., Scavuzzo, Marissa A., Morton, Andrew R., Gevorgyan, Artur S., Cohn, Erin F., Clayton, Benjamin L.L., Bederman, Ilya R., Hung, Stevephen, Bartels, Cynthia F., Madhavan, Mayur, Tesar, Paul J.

“…Mammalian cells respond to insufficient oxygen through transcriptional regulators called hypoxia-inducible factors (HIFs). Although transiently protective,…”
Get full text

Complicanze della nefrolitotrissia percutanea by Scavuzzo, A., Granata, A., Saita, A., Fiorini, F.

“…L'obiettivo di questo studio è descrivere “step-by-step” la nefrolitotrissia percutanea e le sue complicanze. A tale proposito sono stati valutati i casi di…”
Get full text

Generation of Scaffold-free, Three-dimensional Insulin Expressing Pancreatoids from Mouse Pancreatic Progenitors In Vitro by Scavuzzo, Marissa A, Teaw, Jessica, Yang, Diane, Borowiak, Malgorzata

“…The pancreas is a complex organ composed of many different cell types that work together to regulate blood glucose homeostasis and digestion. These cell types…”
Get full text

A 65 nm 1 Gb 2b/cell NOR Flash With 2.25 MB/s Program Throughput and 400 MB/s DDR Interface by Villa, C., Vimercati, D., Schippers, S., Polizzi, S., Scavuzzo, A., Perroni, M., Gaibotti, M., Sali, M.L.

“…This paper describes a 1.8 V, 1 Gb 2 b/cell NOR flash memory, based on time-domain voltage-ramp reading concept and designed in a 65 nm technology. Program…”
Get full text

High self-reactivity drives T-bet and potentiates Treg function in tissue-specific autoimmunity by Sprouse, Maran L, Scavuzzo, Marissa A, Blum, Samuel, Shevchenko, Ivan, Lee, Thomas, Makedonas, George, Borowiak, Malgorzata, Bettini, Matthew L, Bettini, Maria

“…T cell receptor (TCR) affinity is a critical factor of Treg lineage commitment, but whether self-reactivity is a determining factor in peripheral Treg function…”
Get full text