Search Results - "Scarth, A."

The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer by Patterson, Molly R., Cogan, Joseph A., Cassidy, Rosa, Theobald, Daisy A., Wang, Miao, Scarth, James A., Anene, Chinedu A., Whitehouse, Adrian, Morgan, Ethan L., Macdonald, Andrew

“…Human papillomaviruses (HPVs) cause most cervical cancers and an increasing number of anogenital and oral carcinomas, with most cases caused by HPV16 or HPV18…”
Get full text

Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling by Scarth, James A., Wasson, Christopher W., Patterson, Molly R., Evans, Debra, Barba-Moreno, Diego, Carden, Holli, Cassidy, Rosa, Whitehouse, Adrian, Mankouri, Jamel, Samson, Adel, Morgan, Ethan L., Macdonald, Andrew

“…Persistent infection with high-risk human papillomaviruses (HPVs) is the causal factor in multiple human malignancies, including >99% of cervical cancers and a…”
Get full text

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation by Scarth, James A, Patterson, Molly R, Morgan, Ethan L, Macdonald, Andrew

“…Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in over 99 % of cervical cancer cases, and a significant proportion…”
Get full text

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer by Morgan, Ethan L., Scarth, James A., Patterson, Molly R., Wasson, Christopher W., Hemingway, Georgia C., Barba-Moreno, Diego, Macdonald, Andrew

“…Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing to ~5% of all human cancers including almost all cases of cervical cancer…”
Get full text

The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer by Morgan, Ethan L., Patterson, Molly R., Barba-Moreno, Diego, Scarth, James A., Wilson, Adam, Macdonald, Andrew

“…Protein ubiquitination is a critical regulator of cellular homeostasis. Aberrations in the addition or removal of ubiquitin can result in the development of…”
Get full text

CREB1 activation promotes human papillomavirus oncogene expression and cervical cancer cell transformation by Li, Yigen, Patterson, Molly R., Morgan, Ethan L., Wasson, Christopher W., Ryder, Emma L., Barba‐Moreno, Diego, Scarth, James A., Wang, Miao, Macdonald, Andrew

“…Human papillomaviruses (HPVs) infect the oral and anogenital mucosa and can cause cancer. The high‐risk (HR)‐HPV oncoproteins, E6 and E7, hijack cellular…”
Get full text

E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer by Patterson, Molly R., Meijers, Aniek S., Ryder, Emma L., Wootton, Louisa M., Scarth, James A., Evans, Debra, Turner, Amy L., Wasson, Christopher W., Darell, Janne E., Theobald, Daisy A., Cogan, Joseph A., James, Claire D., Wang, Miao, Ladbury, John E., Morgan, Iain M., Samson, Adel, Morgan, Ethan L., Macdonald, Andrew

“…Human papillomaviruses (HPV) are a major cause of malignancy, contributing to ~5% of all human cancers worldwide, including most cervical cancer cases and a…”
Get full text

Effects of curvature on ductile fracture initiation in curved compact tension specimens of hydrided irradiated Zr-2.5Nb materials with split circumferential hydrides by Sung, Shin-Jang, Pan, Jwo, St Lawrence, Sterling, Scarth, Douglas A.

“…•Present different J and K along crack fronts in CCT and CT specimens.•Present different near-tip stresses in CCT and CT specimens.•Determine lower fracture…”
Get full text

Ductile fracture initiation with consideration of strain concentration and stress triaxiality near crack fronts in compact tension specimens of hydrided irradiated Zr-2.5Nb materials with split circumferential hydrides by Sung, Shin-Jang, Pan, Jwo, Lam, Poh-Sang, Scarth, Douglas A.

“…•Provide tensile true stress-plastic strain curve for irradiated Zr-2.5Nb materials.•Determine fracture patterns of radial and circumferential hydrides near…”
Get full text

Ductile fracture initiation near axial crack fronts in pressure tubes of hydrided irradiated Zr-2.5Nb materials with split circumferential hydrides by Sung, Shin-Jang, Pan, Jwo, Lam, Poh-Sang, Scarth, Douglas A.

“…•Determine near-tip stresses and J-integral along axial crack front in pressure tube.•Determine fracture patterns of radial and circumferential hydrides near…”
Get full text

Victims from volcanic eruptions : a revised database by TANGUY, J.-C, RIBIERE, C, SCARTH, A, TJETJEP, W. S

“…The number of victims from volcanism and the primary cause(s) of death reported in the literature show considerable uncertainty. We present the results of…”
Get full text

The use of failure assessment diagrams to describe delayed hydride cracking initiation at a blunt flaw by Scarth, Douglas A., Smith, Ted

“…Delayed hydride cracking (DHC) in Zr–2.5Nb alloy material is of interest to the CANadian Deuterium Uranium (CANDU) (1) industry in the context of the potential…”
Get full text

Geology of the continental margins: G. Boillot; transl. by A. Scarth by Boillot, G, Scarth, A

Get more information

Long-term increases in dentate granule cell responsivity accompany operant conditioning by Skelton, RW, Scarth, AS, Wilkie, DM, Miller, JJ, Phillips, AG

“…The efficacy of synaptic transmission from the perforant path (PP) to the granule cells in the dentate gyrus (DG) of freely moving rats was monitored…”
Get full text

Finite element analyses of crack extensions in curved compact tension specimens of irradiated Zr-2.5Nb pressure tube materials by nodal release method and cohesive zone modeling approach by Wu, Shengjia, Pan, Jwo, Scarth, Douglas A.

“…•Consider plastic orthotropy due to fabrication for irradiated Zr-2.5Nb materials.•Model crack growth in CCT specimens by 2D and 3D FE analyses using nodal…”
Get full text

Rice and the ecological environment in the Camargue by Scarth, A.

Get full text

Microstructure-based polycrystalline finite element modeling of Inconel X-750 irradiated in a CANDU reactor by Xu, Steven, Griffiths, Malcolm, Scarth, Douglas A., Graham, Dave

“…•Simulated the observed inter-granular fracture in Inconel X-750 spacers by a cohesive zone model.•Predicted grain boundary coverages of He bubbles using a…”
Get full text

Tolerance of oxide wedging crack growth of manufacturing flaws in CANDU Zr-2.5Nb pressure tubes to cyclic operating stresses by Gallacher, Tom R., Scarth, Douglas A., Doddihal, Preeti

“…•Oxide wedging crack growth postulated for CANDU pressure tube manufacturing flaws.•Compressibility of oxide wedge is insignificant deviation from displacement…”
Get full text

The Villerest Dam and the control of the Loire by Scarth, A.

Get full text

Nisyros Volcano by Scarth, A.

“…The changes since the beginning of the Quaternary in the volcanic development of Nisyros, in the Aegean Sea, are described. The sequence began with the growth…”
Get full text