Search Results - "Scarpa, R C"

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    Characterization of Copper Interactions with Alzheimer Amyloid beta Peptides. Identification of an Attomolar-Affinity Copper Binding Site on Amyloid beta 1-42 by Atwood, C S, Scarpa, R C, Huang, Xudong, Moir, R D, Jones, W D, Fairlie, D P, Tanzi, R E, Bush, AI

    Published in Journal of neurochemistry (01-09-2000)
    “…Cu and Zn have been shown to accumulate in the brains of Alzheimer's disease patients. We have previously reported that Cu super(2+) and Zn super(2+) bind…”
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    Journal Article
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    Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis by Atwood, Craig S., Moir, Robert D., Huang, Xudong, Scarpa, Richard C., Bacarra, N. Michael E., Romano, Donna M., Hartshorn, Mariana A., Tanzi, Rudolph E., Bush, Ashley I.

    Published in The Journal of biological chemistry (22-05-1998)
    “…The cortical deposition of Aβ is an event that occurs in Alzheimer's disease, Down's syndrome, head injury, and normal aging. Previously, in appraising the…”
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    Journal Article
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    The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction by Huang, Xudong, Atwood, Craig S, Hartshorn, Mariana A, Multhaup, Gerd, Goldstein, Lee E, Scarpa, Richard C, Cuajungco, Math P, Gray, Danielle N, Lim, James, Moir, Robert D, Tanzi, Rudolph E, Bush, Ashley I

    Published in Biochemistry (Easton) (15-06-1999)
    “…Oxidative stress markers characterize the neuropathology both of Alzheimer's disease and of amyloid-bearing transgenic mice. The neurotoxicity of amyloid Aβ…”
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    Copper catalyzed oxidation of Alzheimer Abeta by Atwood, C S, Huang, X, Khatri, A, Scarpa, R C, Kim, Y S, Moir, R D, Tanzi, R E, Roher, A E, Bush, A I

    “…Abeta derived from amyloid plaques of Alzheimer's disease-affected brain contain several oxidative posttranslational modifications. In this study we have…”
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    The effect of neurotensin on insulin-induced proliferation of human fibroblasts by Scarpa, Richard C., Carraway, Robert E., Cochrane, David E.

    Published in Peptides (New York, N.Y. : 1980) (01-07-2004)
    “…Neurotensin has been shown to influence growth in a number of cancerous and non-cancerous cells and to enhance the proliferative effects of growth factors…”
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    Characterization of copper interactions with alzheimer amyloid β peptides : Identification of an attomolar-affinity copper binding site on amyloid β1-42 by ATWOOD, C. S, SCARPA, R. C, XUDONG HUANG, MOIR, R. D, JONES, W. D, FAIRLIE, D. P, TANZI, R. E, BUSH, A. I

    Published in Journal of neurochemistry (01-09-2000)
    “…Cu and Zn have been shown to accumulate in the brains of Alzheimer's disease patients. We have previously reported that Cu 2+ and Zn 2+ bind amyloid β (Aβ),…”
    Get full text
    Journal Article
  12. 12

    Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42 by Atwood, C S, Scarpa, R C, Huang, X, Moir, R D, Jones, W D, Fairlie, D P, Tanzi, R E, Bush, A I

    Published in Journal of neurochemistry (01-09-2000)
    “…Cu and Zn have been shown to accumulate in the brains of Alzheimer's disease patients. We have previously reported that Cu(2+) and Zn(2+) bind amyloid beta…”
    Get full text
    Journal Article
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    Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis by Atwood, C S, Moir, R D, Huang, X, Scarpa, R C, Bacarra, N M, Romano, D M, Hartshorn, M A, Tanzi, R E, Bush, A I

    Published in The Journal of biological chemistry (22-05-1998)
    “…The cortical deposition of Abeta is an event that occurs in Alzheimer's disease, Down's syndrome, head injury, and normal aging. Previously, in appraising the…”
    Get full text
    Journal Article
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    Insulin-like growth factor (IGF) induced proliferation of human lung fibroblasts is enhanced by neurotensin by Scarpa, Richard C., Carraway, Robert E., Cochrane, David E.

    Published in Peptides (New York, N.Y. : 1980) (01-11-2005)
    “…Fibroblasts are key cells in tissue repair and important contributors to the inflammatory response. Insulin-like growth factors (IGFs) have been shown to…”
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    Journal Article
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